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Medicina
Volume 50
Issue 4
10.1016/j.medici.2014.09.003
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Medicina is published by MDPI from Volume 54 Issue 1 (2018). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Lithuanian Medical Association, Lithuanian University of Health Sciences, and Vilnius University.
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Case Report

Early prediction of response to cetuximab and radiotherapy by FDG-PET/CT for the treatment of a locoregionally advanced squamous cell carcinoma of the hypopharynx

by
Mindaugas Grybauskas
1,*,
Jean-François Daisne
2,
Eduardas Aleknavičius
3,4 and
Arvydas Burneckis
1
1
Department of Radiation Oncology, National Cancer Institute, Vilnius, Lithuania
2
Department of Radiation Oncology, Clinique et Maternité Sainte-Elisabeth, Namur, Belgium
3
Radiotherapy and Drug Therapy Centre, National Cancer Institute, Vilnius, Lithuania
4
Faculty of Medicine, Vilnius University, Vilnius, Lithuania
*
Author to whom correspondence should be addressed.
Medicina 2014, 50(4), 245-248; https://doi.org/10.1016/j.medici.2014.09.003
Submission received: 16 May 2014 / Accepted: 15 September 2014 / Published: 29 September 2014
Versions Notes

Abstract

Cetuximab (CTX) is used for the concurrent treatment with radiotherapy (RT) in squamous cell carcinoma of head and neck (HNSCC). There are no reliable clinical predictive markers of effectiveness of CTX at yet. We describe the clinical case of patient who received a CTX/RT to cure locoregionally advanced hypopharyngeal SCC. 2-Deoxy-2-[18F]fluoro-D-glucose positron emission tomography and computed tomography (18FDG-PET/CT) was performed before the treatment and repeated 10 days after CTX induction dose. A repeated 18FDGPET/ CT scan showed dramatic decrease of metabolic parameters. Patient had a complete response after treatment and is still alive and cured after 5 years.
Keywords: Cetuximab; Head and neck cancer; Predictive marker; FDG-PET/CT; Radiotherapy Cetuximab; Head and neck cancer; Predictive marker; FDG-PET/CT; Radiotherapy

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MDPI and ACS Style

Grybauskas, M.; Daisne, J.-F.; Aleknavičius, E.; Burneckis, A. Early prediction of response to cetuximab and radiotherapy by FDG-PET/CT for the treatment of a locoregionally advanced squamous cell carcinoma of the hypopharynx. Medicina 2014, 50, 245-248. https://doi.org/10.1016/j.medici.2014.09.003

AMA Style

Grybauskas M, Daisne J-F, Aleknavičius E, Burneckis A. Early prediction of response to cetuximab and radiotherapy by FDG-PET/CT for the treatment of a locoregionally advanced squamous cell carcinoma of the hypopharynx. Medicina. 2014; 50(4):245-248. https://doi.org/10.1016/j.medici.2014.09.003

Chicago/Turabian Style

Grybauskas, Mindaugas, Jean-François Daisne, Eduardas Aleknavičius, and Arvydas Burneckis. 2014. "Early prediction of response to cetuximab and radiotherapy by FDG-PET/CT for the treatment of a locoregionally advanced squamous cell carcinoma of the hypopharynx" Medicina 50, no. 4: 245-248. https://doi.org/10.1016/j.medici.2014.09.003

APA Style

Grybauskas, M., Daisne, J. -F., Aleknavičius, E., & Burneckis, A. (2014). Early prediction of response to cetuximab and radiotherapy by FDG-PET/CT for the treatment of a locoregionally advanced squamous cell carcinoma of the hypopharynx. Medicina, 50(4), 245-248. https://doi.org/10.1016/j.medici.2014.09.003

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