Helicobacter pylori Infection and Psoriasis: A Systematic Review and Meta-Analysis
Abstract
:1. Introduction
2. Materials and Methods
2.1. Search Strategy
2.2. Selection Criteria
2.3. Data Extraction and Quality Assessment
2.4. Statistical Analysis
3. Results
3.1. Literature Search and Study Characteristics
3.2. Psoriasis and H. pylori Infection Rates
3.3. Subgroup Analysis
3.4. Sensitivity Analyses and Publication Bias
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Conflicts of Interest
References
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Study (Year) | Location | Study Design | Total Cases (Patients/Control) | Women (%) | Mean Age | Mean PASI | Outcomes | NOS Quality Assessment Score |
---|---|---|---|---|---|---|---|---|
Dauden E 2000 [18] | Spain (Europe) | Case-control | 165 (84/81) | NA | NA | NA | Positive urea breath test | 5 |
Campanati A 2015 [19] | Italy (Europe) | Cohort study | 360 (210/150) | 48.1 | 49.75 | 14.56 ± 4.35 | Positive urea breath test | 9 |
Ghada F 2010 [20] | Egypt (Africa) | Cross-sectional study | 40 (20/20) | 20 | 26–55 | PASI < 15 = 3 PASI 15-25 = 7 PASI > 25 = 10 | Positive H.pylori IgG ELISA test | 9 |
Onsun N 2012 [21] | Turkey (Asia) | Cohort study | 450 (300/150) | 49 | 41.65 | 3.94 ± 4.99 | Positive stool antigen test | 7 |
Fabrizi G 2001 [22] | Italy (Europe) | Case-control | 49 (20/29) | 44.9 | 5~19 | NA | Positive urea breath test | 6 |
Zhelezova G 2015 [23] | Bulgaria (Europe) | Cross-sectional study | 49 (25/24) | 32 | 52.2 | NA | Positive H.pylori IgG ELISA test | 7 |
Qayoom S 2003 [24] | India (Asia) | Cross-sectional study | 100 (50/50) | 44 | 5–60 | NA | Positive H.pylori IgG ELISA test | 8 |
Türkmen D 2011 [25] | Turkey (Asia) | Cross-sectional study | 113 (56/57) | 42.9 | 38.4 | 5.89 | Positive urea breath test | 8 |
Azizzadeh M 2014 [26] | Iran (Asia) | Case-control | 122 (61/61) | 54 | 33.3 | 6.6 ± 3.1 | Positive H.pylori IgG ELISA test | 7 |
Mesquita P 2017 [27] | Brazil (South America) | Cohort study | 147 (126/21) | 57.9 | 50.48 | PASI < 5 = 21 PASI 5-10 = 40 PASI > 10 = 65 | Positive H.pylori IgG ELISA test | 7 |
Xunsheng X 2013 [28] | China (Asia) | Case-control | 146 (86/60) | 41 | 16.5–70.5 | 17.42 ± 3.43 | Positive urea breath test | 7 |
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Yu, M.; Zhang, R.; Ni, P.; Chen, S.; Duan, G. Helicobacter pylori Infection and Psoriasis: A Systematic Review and Meta-Analysis. Medicina 2019, 55, 645. https://doi.org/10.3390/medicina55100645
Yu M, Zhang R, Ni P, Chen S, Duan G. Helicobacter pylori Infection and Psoriasis: A Systematic Review and Meta-Analysis. Medicina. 2019; 55(10):645. https://doi.org/10.3390/medicina55100645
Chicago/Turabian StyleYu, Mingyang, Rongguang Zhang, Peng Ni, Shuaiyin Chen, and Guangcai Duan. 2019. "Helicobacter pylori Infection and Psoriasis: A Systematic Review and Meta-Analysis" Medicina 55, no. 10: 645. https://doi.org/10.3390/medicina55100645