Antioxidant Capacity of Preterm Neonates Assessed by Hydrogen Donor Value
Abstract
:1. Introduction
2. Materials and Methods
Blood Sample
3. Results
3.1. Characteristic of the Groups
3.2. Blood Gas Parameters
3.3. Hydrogen Donors
4. Discussions
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Characteristic | All (n = 24) | Girls (n = 14) | Boys (n = 10) | Stat (p-Value) |
---|---|---|---|---|
Gender a | 24 | 14 | 10 | −1.59 (0.1123) |
Gestational age, weeks b | 32.5 (31 to 35) | 33 (31.25 to 34.75) | 32 (31 to 34.25) | 0.61 (0.5387) |
Weight, g b | 1550 (1375 to 1900) | 1500 (1405 to 1890) | 1650 (1365 to 1875) | 0.00 (0.9999) |
Apgar 1 min b | 7 (6 to 8) | 6 (3 to 7) | 7 (7 to 9) | −1.76 (0.0790) |
Apgar 5 min b | 8 (7 to 9) | 7 (6.25 to 8) | 8.5 (8 to 9) | −1.73 (0.0841) |
Respiratory distress c mild moderate severe | 15/24 3/24 4/24 | 9/14 1/14 2/14 | 6/10 2/10 2/10 | n.a. (0.8209) |
Intraventricular hemorrhage c | 5/24 | 2/14 | 3/10 | n.a. (0.6146) |
Blood Gas Parameters | 1st Day | 3rd Day | Stat (p-Value) |
---|---|---|---|
FiO2 (n = 24) | 40.00 b (35.00 to 42.50) | 25.00 b (24.50 to 30.00) | 3.74 (0.0002) |
pH (n = 24) | 7.30 b (7.30 to 7.34) | 7.35 b (7.32 to 7.35) | 2.84 (0.0046) |
pCO2 (n = 24) | 38.00 b (35.00 to 40.50) | 35.00 b (30.90 to 40.00) | 1.48 (0.1396) |
pO2 (n = 24) | 49.75 b (45.00 to 50.55) | 55.00 b (55.00 to 58.15) | 2.94 (0.0033) |
SaO2 (n = 24) | 80.00 b (80.00 to 90.00) | 90.00 b (85.75 to 93.50) | 3.68 (0.0002) |
HD (n = 24) | 43.75 b (39.95 to 52.28) | 49.10 b (44.83 to 56.09) | 2.39 (0.0170) |
1st Day | 3rd Day | Stat (p-Value) | |
---|---|---|---|
Mild (n = 15) Stat (p-value) * | 42.20 b (39.80–45.30) −3.11 (0.0019) | 46.65 b (41.53–52.05) −2.09 (0.0369) | 2.42 (0.0157) |
Moderate (n = 3) Stat (p-value) * | 62.70 b (59.40–64.20) 1.55 (0.1218) | 61.50 b (60.43–64.35) 1.68 (0.0926) | 0.00 (0.9999) |
Severe (n = 4) Stat (p-value) * | 48.30 b (46.48–51.31) −1.02 (0.3082) | 49.60 b (45.30–54.00) −0.91 (0.3650) | 0.00 (0.9999) |
Cerebral Hemorrhage | 1st Day | 3rd Day | Stat (p-Value) * |
---|---|---|---|
Absent (n = 19) | 56.10 b (47.30–62.70) | 59.36 b (47.20–61.50) | 0.40 (0.6858) |
Present (n = 5) | 42.40 b (39.80–47.30) | 49.00 b (43.75–52.50) | 2.74 (0.0062) |
Stat (p-value) ** | −2.31 (0.0209) | −1.07 (0.2863) |
Group (n) | Median (Q1 to Q3) | Z-Value-Mann-Whitney test (p-Value) | |
---|---|---|---|
Control (n = 14) | HD | 53.90 (48.60 to 56.90) | |
Case (n = 24) | HD 1 | 43.75 (39.95 to 52.28) | −2.56 (0.0104) |
HD DOL1 | Apgar 5 | Weight (g) | ||
---|---|---|---|---|
Case | Median | 43.75 | 8 | 1550 |
Q1 | 39.95 | 7 | 1375 | |
Q3 | 52.28 | 9 | 1900 | |
45.82 | 7 | 1591 | ||
10.36 | 2 | 393 |
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Matyas, M.; Hasmasanu, M.G.; Zaharie, G. Antioxidant Capacity of Preterm Neonates Assessed by Hydrogen Donor Value. Medicina 2019, 55, 720. https://doi.org/10.3390/medicina55110720
Matyas M, Hasmasanu MG, Zaharie G. Antioxidant Capacity of Preterm Neonates Assessed by Hydrogen Donor Value. Medicina. 2019; 55(11):720. https://doi.org/10.3390/medicina55110720
Chicago/Turabian StyleMatyas, Melinda, Monica G. Hasmasanu, and Gabriela Zaharie. 2019. "Antioxidant Capacity of Preterm Neonates Assessed by Hydrogen Donor Value" Medicina 55, no. 11: 720. https://doi.org/10.3390/medicina55110720