High HOMA-IR Index in Healthcare Shift Workers

Ledda, Caterina; Cinà, Diana; Matera, Serena; Mucci, Nicola; Bracci, Massimo; Rapisarda, Venerando

doi:10.3390/medicina55050186

Open AccessArticle

High HOMA-IR Index in Healthcare Shift Workers

by

Caterina Ledda

^1,*

,

Diana Cinà

²,

Serena Matera

¹,

Nicola Mucci

³

,

Massimo Bracci

⁴

and

Venerando Rapisarda

¹

Occupational Medicine, Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy

²

Clinical Pathology and Clinical Molecular Biology Unit, “Garibaldi Centro” Hospital of Catania, 95124 Catania, Italy

³

Occupational Medicine, Department of Experimental and Clinical Medicine, University of Florence, 50134 Florence, Italy

⁴

Occupational Medicine, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, 60100 Ancona, Italy

^*

Author to whom correspondence should be addressed.

Medicina 2019, 55(5), 186; https://doi.org/10.3390/medicina55050186

Submission received: 17 January 2019 / Revised: 12 February 2019 / Accepted: 16 May 2019 / Published: 22 May 2019

(This article belongs to the Special Issue Type 2 Diabetes and Insulin Resistance)

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Abstract

Background and objectives: Evidence shows that shift work may be correlated with insulin resistance (IR). Therefore its estimation in clinical and prevention practice is of great significance. A cross-sectional study was performed to examine the Homeostasis Model Assessment-Insulin Resistance (HOMA-IR) Index among healthcare shift workers (HCSW). Materials and Methods: A total of 272 healthcare workers (HCWs) were invited to participate in the study within an occupational surveillance framework, 137 were HCSW while 135 were healthcare non-shift workers (HCNSW). Fasting glucose, insulin, and HOMA-IR Index were evaluated in each participant and correlated with shift workers. Results: Indicators of glucose metabolism were significantly higher in HCSW p < 0.001, and logistic regression analysis confirmed a significant positive association between increased values of HOMA-IR Index and shift workers (p < 0.05). Conclusions: Shift work could be a risk factor in developing insulin resistance and metabolic syndrome.

Keywords: insulin resistance; metabolic syndrome; diabetes; shift work; night work; circadian rhythm; workers

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MDPI and ACS Style

Ledda, C.; Cinà, D.; Matera, S.; Mucci, N.; Bracci, M.; Rapisarda, V. High HOMA-IR Index in Healthcare Shift Workers. Medicina 2019, 55, 186. https://doi.org/10.3390/medicina55050186

AMA Style

Ledda C, Cinà D, Matera S, Mucci N, Bracci M, Rapisarda V. High HOMA-IR Index in Healthcare Shift Workers. Medicina. 2019; 55(5):186. https://doi.org/10.3390/medicina55050186

Chicago/Turabian Style

Ledda, Caterina, Diana Cinà, Serena Matera, Nicola Mucci, Massimo Bracci, and Venerando Rapisarda. 2019. "High HOMA-IR Index in Healthcare Shift Workers" Medicina 55, no. 5: 186. https://doi.org/10.3390/medicina55050186

APA Style

Ledda, C., Cinà, D., Matera, S., Mucci, N., Bracci, M., & Rapisarda, V. (2019). High HOMA-IR Index in Healthcare Shift Workers. Medicina, 55(5), 186. https://doi.org/10.3390/medicina55050186

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High HOMA-IR Index in Healthcare Shift Workers

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