Phase Lag Entropy as a Surrogate Measurement of Hypnotic Depth during Sevoflurane Anesthesia
Abstract
:1. Introduction
2. Materials and Methods
2.1. Patient Population
2.2. Study Procedure
2.3. Correlation between Phase-Lag Entropy and End-Tidal Sevoflurane Concentration
2.4. Pharmacodynamic Modeling
2.5. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Variables | |
---|---|
Age (years) | 50.00 (37.00–53.25) |
Sex (male/female) | 8/5 (62%/38%) |
Height (cm) | 166.50 (160.80–171.28) |
Weight (kg) | 66.10 (62.75–73.83) |
ASA classification (Ⅰ/Ⅱ) | 8/5 (62%/38%) |
BMI (kg/m2) | 25.51 (23.46–26.24) |
Anesthesia time (min) | 185.00 (116.25–202.50) |
Type of surgery | |
Neck mass removal | 3 (23%) |
Tympanoplasty | 8 (62%) |
Parotid tumor removal | 2 (15%) |
Parameter | Estimates (RSE, %) | CV (%) | Median (2.5–97.5%) |
---|---|---|---|
E0 | 84.9 (0.79) | ‒ | 85.0 (82.9–86.8) |
Emax | 42 (5.76) | 18.73 | 41.6 (38.7–45) |
Ce50,vol% | 1.81 (8.95) | 27.82 | 1.80 (1.8–2.1) |
γ | 4.78 (10.61) | ‒ | 4.92 (4.5–5.5) |
ke0 | 0.692 (33.82) | 67.68 | 0.673 (0.42–0.80) |
2 | 1 | ‒ | ‒ |
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Kim, K.-M.; Lee, K.-H.; Park, J.-H. Phase Lag Entropy as a Surrogate Measurement of Hypnotic Depth during Sevoflurane Anesthesia. Medicina 2021, 57, 1034. https://doi.org/10.3390/medicina57101034
Kim K-M, Lee K-H, Park J-H. Phase Lag Entropy as a Surrogate Measurement of Hypnotic Depth during Sevoflurane Anesthesia. Medicina. 2021; 57(10):1034. https://doi.org/10.3390/medicina57101034
Chicago/Turabian StyleKim, Kyung-Mi, Ki-Hwa Lee, and Jae-Hong Park. 2021. "Phase Lag Entropy as a Surrogate Measurement of Hypnotic Depth during Sevoflurane Anesthesia" Medicina 57, no. 10: 1034. https://doi.org/10.3390/medicina57101034