Non-IgE Mediated Hypersensitivity to Food Products or Food Intolerance—Problems of Appropriate Diagnostics
Abstract
:1. Introduction
2. Material and Methods
3. Results—Case Reports
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Kind of Food | Case 1 | Case 2 | Case 3 | Case 4 | ||||
---|---|---|---|---|---|---|---|---|
Cytotoxic Test (Metabolic Code 203) | IgG4 (mgA/l) | Cytotoxic Test (Metabolic Code 203) | IgG4 (mgA/l) | Test ImuPro | IgG4 (mgA/l) | Test ImuPro | IgG4 (mgA/l) | |
Peach | 0 | 2.68 | 0 | 4.1 | No test | 0.51 | No test | 1.53 |
Egg | 0 | 23.1 | +2 | 3.41 | Extremely high >20 mg IgG/ml | 5.46 | +1 (7.54–12.49 mg IgG/mL) | 1.44 |
Cow milk (casein *) | +1 | 1.26 | +3 | 0.81 | Increased >7.5 mg IgG/ml | 1.49 | Not increased | 0.36 |
Peanuts | No test; +2 (walnuts), +3 (hazel) | 0.05 | +3 +2 (walnuts) | 0.03 | No test | 1.07 | +2 (12.5–19.9 mg IgG/mL) | 0.01 |
Grains (omega-5-gliadine *) | +3 (wheat) | 0.01 | +2 (wheat) | 0.01 | Only wheat-increased | 0.03 | +3 (gluten) (20–49.9 mg IgG/mL) +3 (wheat) (20–49.9 mg IgG/mL) | 0.01 |
Fish | +1/+3 (different genera) | 0.00 | +1/+3 (different genera) | 0.01 | No test | 0.01 | +1 (plaice) | 0.00 |
Symptoms Severity after Food Consumption before Elimination and after Products Reintroduction | ||||||||
---|---|---|---|---|---|---|---|---|
Case 1 | Case 2 | Case 3 | Case 4 | |||||
Food Products (Allergens *) | Before Elimination | After Reintroduction | Before Elimination | After Reintroduction | Before Elimination | After Reintroduction | Before Elimination | After Reintroduction |
Peach | No symptoms | No elimination | No symptoms | No symptoms (OAS possible) | No symptoms | No elimination | No symptoms | No symptoms |
Egg | No symptoms | No symptoms | No symptoms | No symptoms | Symptoms | Symptoms (slight) | No symptoms | No symptoms |
Cow milk (casein *) | Symptoms | Symptoms | Symptoms | No elimination | Symptoms | Symptoms | Symptoms | Symptoms (slight) |
Peanuts | No symptoms | No elimination | No symptoms | No elimination | No symptoms | No elimination | No symptoms | No elimination |
Grains (omega-5-gliadine *) | Symptoms | Symptoms | Symptoms | Symptoms | Symptoms | No elimination | Symptoms | Symptoms (slight) |
Fish | No symptoms | No elimination | No symptoms | No elimination | No symptoms | No elimination | No symptoms | No elimination |
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Myszkowska, D.; Zapała, B.; Bulanda, M.; Czarnobilska, E. Non-IgE Mediated Hypersensitivity to Food Products or Food Intolerance—Problems of Appropriate Diagnostics. Medicina 2021, 57, 1245. https://doi.org/10.3390/medicina57111245
Myszkowska D, Zapała B, Bulanda M, Czarnobilska E. Non-IgE Mediated Hypersensitivity to Food Products or Food Intolerance—Problems of Appropriate Diagnostics. Medicina. 2021; 57(11):1245. https://doi.org/10.3390/medicina57111245
Chicago/Turabian StyleMyszkowska, Dorota, Barbara Zapała, Małgorzata Bulanda, and Ewa Czarnobilska. 2021. "Non-IgE Mediated Hypersensitivity to Food Products or Food Intolerance—Problems of Appropriate Diagnostics" Medicina 57, no. 11: 1245. https://doi.org/10.3390/medicina57111245