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Volume 57
Issue 12
10.3390/medicina57121298
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Case Report

A Challenge of COVID—19: Associated Infective Endocarditis with Streptococcus gordonii in a Young Immunocompetent Patient

by
Manuela Arbune
1,*,
Alina-Viorica Iancu
2,
Gabriela Lupasteanu
3,*,
Mihaela-Camelia Vasile
1 and
Victorita Stefanescu
2
1
Clinical Department, Medicine and Pharmacy Faculty, Dunarea de Jos University of Galati, 800008 Galati, Romania
2
Morphological and Functional Science Department, Medicine and Pharmacy Faculty, Dunarea de Jos University of Galati, 800008 Galati, Romania
3
Doctoral School, Ovidius University of Constanta, 800179 Galati, Romania
*
Authors to whom correspondence should be addressed.
Medicina 2021, 57(12), 1298; https://doi.org/10.3390/medicina57121298
Submission received: 26 October 2021 / Revised: 18 November 2021 / Accepted: 24 November 2021 / Published: 26 November 2021
(This article belongs to the Special Issue Infections and Infectious Diseases: Epidemiology, Mechanisms of Infection and Treatment Options)
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Abstract

The COVID-19 pandemic is a new challenge for the diagnosis and treatment of infective endocarditis (IE). Fever and other unspecific symptoms of coronaviral infection could be misleading or masking its manifestations. We present the case of a young patient admitted for persistent fever, profuse sweating, headache, articular pain, myalgias, and weight loss. She reported regression taste and smell disorders compared to a month earlier when diagnosed with moderate COVID-19 pneumonia. While the RT-PCR SARS-COV-2 test was positive, she was admitted to a COVID-19 ward. Investigations of febrile syndrome revealed two positive blood cultures with Streptococcus gordonii and the presence of vegetations on the aortic valve, supporting a certain diagnosis of IE. After six weeks of antibiotic treatment, the patient had clinical and biologic favorable outcomes. Streptococcus gordonii is a common commensal related to the dental biofilm, although there were no caries in our patient. The influence of COVID-19 infection on the human microbiome by modifying the virulence of some commensal germs may be a risk factor for IE pathogenesis on native valves and requires the vigilance of clinicians for suspicion of this disease.
Keywords: COVID-19; Streptococcus gordonii; infectious endocarditis; oral microbiome COVID-19; Streptococcus gordonii; infectious endocarditis; oral microbiome

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MDPI and ACS Style

Arbune, M.; Iancu, A.-V.; Lupasteanu, G.; Vasile, M.-C.; Stefanescu, V. A Challenge of COVID—19: Associated Infective Endocarditis with Streptococcus gordonii in a Young Immunocompetent Patient. Medicina 2021, 57, 1298. https://doi.org/10.3390/medicina57121298

AMA Style

Arbune M, Iancu A-V, Lupasteanu G, Vasile M-C, Stefanescu V. A Challenge of COVID—19: Associated Infective Endocarditis with Streptococcus gordonii in a Young Immunocompetent Patient. Medicina. 2021; 57(12):1298. https://doi.org/10.3390/medicina57121298

Chicago/Turabian Style

Arbune, Manuela, Alina-Viorica Iancu, Gabriela Lupasteanu, Mihaela-Camelia Vasile, and Victorita Stefanescu. 2021. "A Challenge of COVID—19: Associated Infective Endocarditis with Streptococcus gordonii in a Young Immunocompetent Patient" Medicina 57, no. 12: 1298. https://doi.org/10.3390/medicina57121298

APA Style

Arbune, M., Iancu, A.-V., Lupasteanu, G., Vasile, M.-C., & Stefanescu, V. (2021). A Challenge of COVID—19: Associated Infective Endocarditis with Streptococcus gordonii in a Young Immunocompetent Patient. Medicina, 57(12), 1298. https://doi.org/10.3390/medicina57121298

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