Value of the Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio in Predicting CPET Performance in Patients with Stable CAD and Recent Elective PCI
Abstract
:1. Introduction
2. Materials and Methods
2.1. Statistical Analysis
2.2. Ethics Statement
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Parameters | All Patients (n = 80) | % VO2 Max >70 (n = 45) | % VO2 Max ≤70 (n = 35) | p Value * |
---|---|---|---|---|
Age (years) × | 55.51 ± 11.83 | 57.02 ± 12.08 | 53.57 ± 11.38 | 0.19 |
NLR × | 1.97 ± 0.80 | 1.83 ± 0.65 | 2.15 ± 0.93 | 0.07 |
PLR × | 155.6 ± 52.7 | 137.4 ± 35.9 | 169.8 ± 59.3 | 0.003 |
Platelet count, ×103/μL × | 256 ± 60 | 244.4 ± 56.1 | 266.3 ± 56.1 | 0.11 |
Neutrophil count, ×103/μL × | 3.32 ± 1.25 | 2.92 ± 0.90 | 3.83 ± 1.45 | 0.001 |
Lymphocyte count, ×103/μL † | 1.72 (1.44–1.99) | 1.45 (1.31–2.43) | 1.86 (1.65–1.88) | 0.06 |
CRP (mg/dl) † | 0.41 (0.24–1.04) | 0.28 (0.15–1.26) | 0.54 (0.26–0.89) | 0.82 |
LVEF × | 51.31 ± 11.04 | 55.67 ± 9.26 | 48.71 ± 10.93 | 0.003 |
BMI (kg/m2) † | 28.7 (27.4–33) | 28.4 (27.4–32.4) | 30.15 (25.82–33.17) | 0.68 |
Hypertension □ | 66 (82.5) | 38 (84.4) | 28 (80) | 0.76 |
Diabetes □ | 22 (27.5) | 14 (31,1) | 8 (22.9) | 0.45 |
HbA1c (%) × | 7.11 ± 1.47 | 6.58 ± 1.10 | 7.67 ± 1.66 | 0.05 |
LDL (mg/dl) † | 84 (69.8–108) | 73(69.8-104) | 100.8 (56.6–124) | 0.57 |
Resting HR × | 81.9 ± 15.69 | 84.00 ± 17.25 | 77.57 ± 12.76 | 0.05 |
% peak HR × | 77.98 ± 12.25 | 82.38 ± 11.21 | 72.31 ± 11.27 | 0.001 |
Resting SBP (mmHg) × | 127.3 ± 12.65 | 130 ± 13.39 | 125.3 ± 11.79 | 0.1 |
Resting DBP (mmHg) × | 81.5 ± 7.52 | 80.78 ± 7.305 | 82.43 ± 7.8 | 0.33 |
Parameters | NLR | PLR | Resting HR | % Peak HR | % Peak WR | % VO2 Max |
---|---|---|---|---|---|---|
NLR | 1 | 0.369 * | −0.087 | −0.043 | −0.104 | −0.133 |
PLR | 0.369 * | 1 | 0.207 | 0.172 | 0.105 | 0.249 * |
Resting HR | −0.087 | 0.207 | 1 | 0.594 * | −0.053 | 0.144 |
% peak HR | −0.043 | 0.172 | 0.594 * | 1 | 360 * | 0.448 * |
% peak WR | −0.104 | 0.105 | −0.053 | 0.360 * | 1 | 0.705 * |
% VO2 max | −0.133 | 0.249 * | 0.144 | 0.448 * | 0.705 * | 1 |
Variables | Odds Ratio | 95% Confidence Interval | p |
---|---|---|---|
Neutrophil count, ×103/μL | 1.00 | 0.999–1.002 | 0.523 |
PLR | 1.015 | 1.004–1.027 | 0.009 |
LVEF | 1.07 | 1.003–1.141 | 0.042 |
% peak HR | 1.088 | 1.029–1.151 | 0.003 |
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Drugescu, A.; Roca, M.; Zota, I.M.; Costache, A.-D.; Gavril, O.I.; Gavril, R.S.; Vasilcu, T.F.; Mitu, O.; Esanu, I.M.; Roca, I.-C.; et al. Value of the Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio in Predicting CPET Performance in Patients with Stable CAD and Recent Elective PCI. Medicina 2022, 58, 814. https://doi.org/10.3390/medicina58060814
Drugescu A, Roca M, Zota IM, Costache A-D, Gavril OI, Gavril RS, Vasilcu TF, Mitu O, Esanu IM, Roca I-C, et al. Value of the Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio in Predicting CPET Performance in Patients with Stable CAD and Recent Elective PCI. Medicina. 2022; 58(6):814. https://doi.org/10.3390/medicina58060814
Chicago/Turabian StyleDrugescu, Andrei, Mihai Roca, Ioana Mădălina Zota, Alexandru-Dan Costache, Oana Irina Gavril, Radu Sebastian Gavril, Teodor Flaviu Vasilcu, Ovidiu Mitu, Irina Mihaela Esanu, Iulia-Cristina Roca, and et al. 2022. "Value of the Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio in Predicting CPET Performance in Patients with Stable CAD and Recent Elective PCI" Medicina 58, no. 6: 814. https://doi.org/10.3390/medicina58060814