Diagnostic and Therapeutic Characteristics in Patients with Pneumotorax Associated with COVID-19 versus Non-COVID-19 Pneumotorax
Abstract
:1. Introduction
2. Materials and Methods
3. Results
4. Discussion
4.1. Treatment Methods for the Pleural Space Management
4.2. Interventional Management (Medical–Surgical Therapeutic Attitude)
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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COVID-19 Associated Pneumothorax n = 34 | Pneumothorax without COVID-19 n = 42 | p-Value | |
---|---|---|---|
Age variation (y-o) | 30–84 | 15–68 | N/A |
Mean age (y-o) | 58.29 | 41.13 | <0.0001 * |
Sex ratio (M:F) | 26:8 | 33:9 | N/A |
Comorbidities | COVID-19 Associated Pneumothorax n = 34 | Pneumothorax without COVID-19 n = 42 | Statistic Test | p-Value |
---|---|---|---|---|
No comorbidity | 0 (0%) | 16 (38.09%) | OR = 0.023 | 0.009 |
Smoker | 16 (47.05%) | 34 (80.95%) | OR = 0.209 | 0.002 |
COPD | 21 (61.76%) | 0 (0%) | OR = 135.37 | 0.0008 |
Asthma | 6 (17.64%) | 0 (0%) | OR = 19.38 | 0.04 |
Bronchiectasis | 26 (76.47%) | 0 (0%) | OR = 265 | 0.0002 |
Systemic hypertension | 18 (52.94%) | 0 (0%) | OR = 95.3 | 0.001 |
Pulmonary emphysema | 5 (14.7%) | 26 (61.9%) | OR = 0.106 | 0.0001 |
Tachycardia | 14 (41.17%) | 0 (0%) | OR = 60.12 | 0.005 |
Heart disease | 16 (47.05%) | 0 (0%) | OR = 75.81 | 0.003 |
COVID-19 Associated Pneumothorax n = 34 | Pneumothorax without COVID-19 n = 42 | Statistic Test | p-Value | |||
---|---|---|---|---|---|---|
Haematology | Range | Average | Range | Average | ||
WBC (k/microL) | 4.20–24.32 | 14.3 | 3.80–8.76 | 7.8 | t-test = 10.29 | <0.0001 |
D_Dimer (ng/mL) | 305–720 | 505 | 0–250 | 125 | t-test = 16.4 | <0.0001 |
Blood chemistry | Range | Average | Range | Average | ||
Ferritin (mg/dL) | 356–833 | 606 | 20.00–250 | 140 | t-test = 20.11 | <0.0001 |
CRP (mg/L) | 28.08–71.3 | 58.1 | 0.00–5.00 | 3 | t-test = 15.44 | <0.0001 |
LD-P (U/L) | 283.69–387.07 | 303.8 | 125.00–220.00 | 176.2 | t-test = 4.55 | <0.0001 |
γGT (U/L) | 63.02–98.75 | 74.6 | 11.00–59.00 | 23.9 | t-test = 4.94 | <0.0001 |
Imaging Diagnosis | ||||||
Right pneumothorax | 25 | 23 | OR = 2.29 | 0.09 | ||
Left pneumothorax | 9 | 19 | OR = 0.43 | 0.09 |
COVID-19 Associated Pneumothorax n = 34 | Pneumothorax without COVID-19 n = 42 | Statistic Test | p-Value | |
---|---|---|---|---|
Dyspnea | 34 (100%) | 42 (100%) | OR = 0.81 | 0.91 |
Persistent cough | 34 (100%) | 1 (2.38%) | OR = 2.49 | 0.57 |
Fever | 34 (100%) | 0 (0%) | OR = 5865 | <0.0001 |
Chest pain | 23 (67.64%) | 42 (100%) | OR = 0.024 | 0.01 |
Therapeutic Attitude | COVID-19 Associated Pneumothorax n = 34 | Pneumothorax without COVID-19 n = 42 | Statistic Test | p-Value |
---|---|---|---|---|
Chest tube drainage | 34 | 12 | OR = 168.36 | 0.0005 |
Video assisted (VATS) procedures * | 0 | 30 | OR = 0.005 | 0.0005 |
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Nistor, C.-E.; Pantile, D.; Stanciu-Gavan, C.; Ciuche, A.; Moldovan, H. Diagnostic and Therapeutic Characteristics in Patients with Pneumotorax Associated with COVID-19 versus Non-COVID-19 Pneumotorax. Medicina 2022, 58, 1242. https://doi.org/10.3390/medicina58091242
Nistor C-E, Pantile D, Stanciu-Gavan C, Ciuche A, Moldovan H. Diagnostic and Therapeutic Characteristics in Patients with Pneumotorax Associated with COVID-19 versus Non-COVID-19 Pneumotorax. Medicina. 2022; 58(9):1242. https://doi.org/10.3390/medicina58091242
Chicago/Turabian StyleNistor, Claudiu-Eduard, Daniel Pantile, Camelia Stanciu-Gavan, Adrian Ciuche, and Horatiu Moldovan. 2022. "Diagnostic and Therapeutic Characteristics in Patients with Pneumotorax Associated with COVID-19 versus Non-COVID-19 Pneumotorax" Medicina 58, no. 9: 1242. https://doi.org/10.3390/medicina58091242