Pre-Surgery Patient Health Contributes to Aggravated Sino-Nasal Outcome and Quality of Life after Pituitary Adenomectomy
Abstract
:1. Introduction
2. Materials and Methods
2.1. Questionnaires
2.1.1. Health-Related Quality of Life (HRQoL)
2.1.2. Sino-Nasal Outcome Test for Neurosurgery (SNOT-NC)
2.1.3. Clinical ad hoc Questions
2.2. Statistical Analyses
2.3. Sample
3. Results
3.1. Sample Characteristics
3.2. SNOT-NC
3.3. SF-36
3.4. Correlation SNOT-NC and SF-36
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Abbreviations
HRQoL | health-related quality of life |
SNOT[-NC] | sino-nasal outcome test [for neurosurgery] |
SF-36 | HRQoL inventory Short Form |
References
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Pre-Surgery Health Variable | Non-Existent (Mean ± SEM) | Existent (Mean ± SEM) | t-Value | p-Value | Cohen’s d |
---|---|---|---|---|---|
SNOT-NC Total Score | |||||
Allergies | 43.77 ± 1.84 | 46.35 ± 2.46 | −0.88 | 0.379 | −184 |
Previous nose surgeries | 43.04 ± 1.79 | 53.57 ± 4.13 | −2.67 | 0.009 | −0.701 |
Presence of any pain | 44.37 ± 1.94 | 48.56 ± 3.69 | −1.08 | 0.285 | −0.269 |
Snoring | 46.47 ± 2.83 | 44.53 ± 2.00 | 0.560 | 0.577 | 0.124 |
Sleep apnea | 45.36 ± 1.72 | 42.42 ± 2.57 | 0.95 | 0.350 | 0.201 |
Cpap | 44.85 ± 1.64 | 43.75 ± 4.08 | 0.20 | 0.842 | 0.074 |
Nose drop usage | 45.54 ± 2.47 | 44.49 ± 1.82 | 0.32 | 0.750 | 0.071 |
SNOT-NC Nasal Discomfort | |||||
Allergies | 13.89 ± 0.62 | 14.78 ± 0.82 | −0.87 | 0.387 | −0.181 |
Previous nose surgeries | 13.77 ± 0.60 | 16.79 ± 1.40 | −2.27 | 0.026 | −0.595 |
Presence of any pain | 14.21 ± 0.66 | 15.18 ± 1.20 | −0.74 | 0.460 | −0.186 |
Snoring | 14.39 ± 0.95 | 14.56 ± 0.67 | −0.15 | 0.882 | −0.033 |
Sleep apnea | 14.28 ± 0.59 | 14.03 ± 0.81 | 0.25 | 0.803 | 0.051 |
Cpap | 14.22 ± 0.56 | 14.25 ± 0.90 | −0.03 | 0.976 | −0.006 |
Nose drop usage | 14.79 ± 0.81 | 14.01 ± 0.62 | 0.71 | 0.482 | 0.158 |
SNOT-NC Sleep Problems/ Reduced Productivity | |||||
Allergies | 10.50 ± 0.56 | 11.65 ± 0.86 | −1.16 | 0.249 | −0.242 |
Previous nose surgeries | 10.19 ± 0.62 | 12.58 ± 1.06 | −1.89 | 0.063 | −495 |
Presence of any pain | 10.42 ± 0.63 | 11.64 ± 1.09 | −0.99 | 0.324 | −0.248 |
Snoring | 10.73 ± 0.80 | 10.78 ± 0.74 | −0.04 | 0.969 | −0.009 |
Sleep apnea | 11.13 ± 0.55 | 10.16 ± 0.89 | 0.80 | 0.426 | 0.204 |
Cpap | 10.99 ± 0.52 | 10.38 ± 1.27 | 0.35 | 0.727 | 0.130 |
Nose drop usage | 10.67 ± 0.78 | 11.04 ± 0.59 | −0.34 | 0.732 | −0.077 |
SNOT-NC Ear/ Head Discomfort | |||||
Allergies | 9.20 ± 0.52 | 9.52 ± 0.64 | −0.39 | 0.701 | −0.080 |
Previous nose surgeries | 8.96 ± 0.49 | 11.57 ± 1.13 | −2.12 | 0.044 | −632 |
Presence of any pain | 9.18 ± 0.50 | 10.62 ± 1.08 | −1.21 | 0.235 | −0.343 |
Snoring | 10.32 ± 0.77 | 8.80 ± 0.52 | 1.63 | 0.107 | 0.361 |
Sleep apnea | 9.52 ± 0.46 | 8.47 ± 0.73 | 1.04 | 0.303 | 0.264 |
Cpap | 9.37 ± 0.44 | 9.25 ± 1.51 | 0.08 | 0.938 | 0.029 |
Nose drop usage | 9.71 ± 0.80 | 9.16 ± 0.46 | 0.63 | 0.532 | 0.139 |
SNOT-NC Visual Impairment | |||||
Allergies | 6.48 ± 0.35 | 6.68 ± 0.49 | −0.34 | 0.734 | −0.071 |
Previous nose surgeries | 6.42 ± 0.34 | 8.16 ± 0.80 | −2.32 | 0.023 | −0.608 |
Presence of any pain | 6.49 ± 0.38 | 7.73 ± 0.62 | −1.71 | 0.092 | −0.426 |
Snoring | 7.39 ± 0.54 | 6.25 ± 0.34 | 1.78 | 0.080 | 0.394 |
Sleep apnea | 6.73 ± 0.33 | 5.79 ± 0.48 | 0.11 | 0.190 | 0.337 |
Cpap | 6.60 ± 0.32 | 6.13 ± 0.99 | 0.44 | 0.658 | 0.164 |
Nose drop usage | 6.25 ± 0.40 | 6.67 ± 0.36 | −0.67 | 0.505 | −0.150 |
Pre-Surgery Health Variable | Non-Existent (Mean ± SEM) | Existent (Mean ± SEM) | t-Value | p-Value | Cohen’s d |
---|---|---|---|---|---|
Psychological HRQoL | |||||
Allergies | 46.44 ± 1.73 | 43.35 ± 2.29 | 1.08 | 0.282 | 0.260 |
Previous nose surgeries | 47.65 ± 1.44 | 37.31 ± 2.95 | 3.36 | 0.001 | 0.927 |
Presence of any pain | 46.48 ± 1.54 | 41.52 ± 2.97 | 1.55 | 0.125 | 0.420 |
Snoring | 46.78 ± 1.98 | 44.10 ± 1.49 | 1.10 | 0.277 | 0.232 |
Sleep apnea | 45.32 ± 1.40 | 45.55 ± 2.54 | −0.08 | 0.941 | −0.020 |
Cpap | 45.39 ± 1.35 | 43.41 ± 2.99 | 0.46 | 0.644 | 0.172 |
Nose drop usage | 46.96 ± 2.18 | 44.65 ± 1.72 | 0.74 | 0.461 | 0.194 |
Physical HRQoL | |||||
Allergies | 44.59 ± 1.68 | 42.98 ± 2.22 | 0.58 | 0.561 | 0.140 |
Previous nose surgeries | 45.01 ± 1.57 | 40.54 ± 2.31 | 1.42 | 0.160 | 0.393 |
Presence of any pain | 45.29 ± 1.53 | 39.91 ± 2.59 | 1.75 | 0.084 | 0.475 |
Snoring | 43.08 ± 1.78 | 44.60 ± 1.56 | −0.65 | 0.520 | −0.137 |
Sleep apnea | 43.32 ± 1.40 | 46.10 ± 1.71 | −0.95 | 0.343 | −0.251 |
Cpap | 43.60 ± 1.33 | 45.91 ± 2.49 | −0.55 | 0.583 | −0.205 |
Nose drop usage | 45.76 ± 2.17 | 43.32 ± 1.64 | 0.81 | 0.422 | 0.211 |
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Chmielewski, W.X.; Walbrodt, S.; Rauschenbach, L.; Chihi, M.; Gembruch, O.; Darkwah Oppong, M.; Schroer, S.; Wrede, K.H.; Dammann, P.; Jabbarli, R.; et al. Pre-Surgery Patient Health Contributes to Aggravated Sino-Nasal Outcome and Quality of Life after Pituitary Adenomectomy. Medicina 2023, 59, 127. https://doi.org/10.3390/medicina59010127
Chmielewski WX, Walbrodt S, Rauschenbach L, Chihi M, Gembruch O, Darkwah Oppong M, Schroer S, Wrede KH, Dammann P, Jabbarli R, et al. Pre-Surgery Patient Health Contributes to Aggravated Sino-Nasal Outcome and Quality of Life after Pituitary Adenomectomy. Medicina. 2023; 59(1):127. https://doi.org/10.3390/medicina59010127
Chicago/Turabian StyleChmielewski, Witold X., Sebastian Walbrodt, Laurèl Rauschenbach, Mehdi Chihi, Oliver Gembruch, Marvin Darkwah Oppong, Sebastian Schroer, Karsten H. Wrede, Philipp Dammann, Ramazan Jabbarli, and et al. 2023. "Pre-Surgery Patient Health Contributes to Aggravated Sino-Nasal Outcome and Quality of Life after Pituitary Adenomectomy" Medicina 59, no. 1: 127. https://doi.org/10.3390/medicina59010127