Using a Modified Polysaccharide as a Hemostatic Agent Results in Less Reduction of the Ovarian Reserve after Laparoscopic Surgery of Ovarian Tumors—Prospective Study
Abstract
:1. Introduction
Aim
2. Materials and Methods
3. Results
4. Discussion
5. Conclusions
- Using a modified polysaccharide during laparoscopic cystectomy is effective and has a positive effect on the ovarian reserve compared to the use of bipolar coagulation.
- The AMH level 6 months after surgery is more favorable in the group of patients treated with modified starch. This is especially important in the group of young women who want to maintain the best possible chance of a future pregnancy.
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Study (Starch) (N= 19) | Control (Coagulation) (N = 19) | p Value | |
---|---|---|---|
Age (years) | 30.8 (+/− 7.05) | 30.2 (+/− 7.08) | 0.80 |
AMH 1 (ng/mL) | 4.1 (0.78–8.56) | 2.9 (0.4–9.78) | 0.34 |
Cyst max. diameter (cm) | 4.5 (2.0–12.5) | 4.5 (1.9–9.0) | 0.98 |
Cyst volume (cm3) | 29.0 (3.14–865.14) | 44.6 (2.0–220.0) | 0.81 |
Contralateral ovarian max diameter (cm) | 2.8 (+/− 0.6) | 2.99 (+/− 0.79) | 0.49 |
Contralateral ovarian volume (cm3) | 8.17 (1.34–20.4) | 9.5 (2.8–37.0) | 0.90 |
Duration of the operation (min) | 37.0 (25.0–60.0) | 40.0 (17.0–82.0) | 0.17 |
Histopathological Diagnosis | Study (Starch) | Control (Coagulation) | Total |
---|---|---|---|
Endometrial cyst | 8 | 9 | 17 |
Adult teratoma | 6 | 4 | 10 |
Serous cyst | 3 | 5 | 8 |
Hemorrhagic cyst | 2 | 1 | 3 |
Total | 19 | 19 | 38 |
Age Group | All | Study (Starch) | Control (Coagulation) | AMH Norm (ng/mL) |
---|---|---|---|---|
20–24 | 9 | 4 | 5 | 1.52–9.95 |
25–29 | 9 | 4 | 5 | 1.2–9.05 |
30–34 | 10 | 5 | 5 | 0.71–7.59 |
35–39 | 5 | 4 | 1 | 0.45–6.96 |
40–44 | 5 | 2 | 3 | 0.059–4.44 |
Total | 38 | 19 | 19 |
Group | AMH 1 | AMH 2 | p Value | |
---|---|---|---|---|
Study (starch) | Mean +/− SD | 3.95 +/− 2.25 | 3.96 +/− 2.12 | 0.98 |
Control (coagulation) | Mean +/− SD | 3.34 +/− 2.02 | 2.51 +/− 1.39 | 0.049 |
Histopathological Diagnosis | p Value | |||||
---|---|---|---|---|---|---|
Cyst | Number | AMH 1 Median | AMH 1 Range | Teratoma | Serous | Hemorrhagic |
Endometrial | 17 | 4.39 | 1.89–9.78 | 0.005 | 0.153 | 0.023 |
Teratoma | 10 | 2.46 | 0.79–4.82 | 0.238 | 0.665 | |
Serous | 8 | 2.82 | 0.4–7.48 | 0.214 | ||
Hemorrhagic | 3 | 1.28 | 1.27–3.59 |
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Moszynski, R.; Burchardt, B.; Sajdak, S.; Moszynska, M.; Englert-Golon, M.; Olbromski, P. Using a Modified Polysaccharide as a Hemostatic Agent Results in Less Reduction of the Ovarian Reserve after Laparoscopic Surgery of Ovarian Tumors—Prospective Study. Medicina 2023, 59, 14. https://doi.org/10.3390/medicina59010014
Moszynski R, Burchardt B, Sajdak S, Moszynska M, Englert-Golon M, Olbromski P. Using a Modified Polysaccharide as a Hemostatic Agent Results in Less Reduction of the Ovarian Reserve after Laparoscopic Surgery of Ovarian Tumors—Prospective Study. Medicina. 2023; 59(1):14. https://doi.org/10.3390/medicina59010014
Chicago/Turabian StyleMoszynski, Rafal, Bartosz Burchardt, Stefan Sajdak, Marta Moszynska, Monika Englert-Golon, and Piotr Olbromski. 2023. "Using a Modified Polysaccharide as a Hemostatic Agent Results in Less Reduction of the Ovarian Reserve after Laparoscopic Surgery of Ovarian Tumors—Prospective Study" Medicina 59, no. 1: 14. https://doi.org/10.3390/medicina59010014