The Antimicrobial Resistance Index and Fournier Gangrene Severity Index of Patients Diagnosed with Fournier’s Gangrene in a Tertiary Hospital in North Eastern Romania
Abstract
1. Introduction
2. Materials and Methods
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Survivors | Deceased | Total | p | |
---|---|---|---|---|
No. of patients | 35 | 5 | 40 | |
Mean age (SD) | 65.57 (±12.84) | 66.8 (±6.11) | 65.72 (±12.21) | 0.75 |
Body temperature (°C) | 38.12 (±0.68) | 38.94 (±0.85) | 38.22 (±0.74) | 0.009 |
Hemoglobin (g/dL) | 11.07 (±2.43) | 10.61 (±1.33) | 11.02 (±2.32) | 0.34 |
WBC | 17.4 (±5.46) | 25.23 (±7.48) | 18.38 (±6.28) | 0.003 |
C reactive protein mg/L | 277.38(±135.78) | 192.62(±168.09) | 265 (±139.67) | 0.174 |
Platelet count (×103/mm3) | 183.78 (±26.56) | 162.32 (±18.63) | 181.45 (±25.32) | 0.08 |
Diabetes mellitus (n) | 57.14% (20) | 60% (3) | 57.5% (23) | 0.9 |
Arterial hypertension (n) | 57.14% (20) | 60% (3) | 57.5% (23) | 0.9 |
Heart rate (bpm) | 98.31 (±7.75) | 106.6 (±10.4) | 99.35 (±8.43) | 0.019 |
CKD (n) | 20% (7) | 40% (2) | 22.5% (9) | 0.31 |
Hepatopathy (n) | 31.42% (11) | 20% (1) | 30% (12) | 0.98 |
Obesity (n) | 14.28% (5) | 60% (3) | 20% (8) | 0.04 |
BMI | 24.47 (±5.21) | 22.01 (±2,74) | 24.17 (±5.01) | 0.16 |
FGSI | 4.17 (±2.80) | 9.4 (±3.2) | 4.8 (±3.31) | 0.0002 |
Mean MAR index | 0.37 (±0.29) | 0.59 (±0.24) | 0.4 (±0.29) | 0.036 |
Length of stay (days) | 19.48 (±7.99) | 9.6 (±12.03) | 18.25 (±9.03) | 0.009 |
Identified Germ | Patients (n=) | Mean MAR Index (a/b) |
---|---|---|
E. coli | 40% (16) | 0.34 |
Klebsiella | 30% (12) | 0.39 |
Enterococcus | 10% (4) | 0.22 |
Pseudomonas | 5% (2) | 0.85 |
Proteus mirabilis | 2.5% (1) | 0.75 |
S. aureus | 5% (2) | 0.62 |
Streptococcus spp. | 2.5% (1) | 0.12 |
Acinetobacter | 2.5% (1) | 1 |
Mixed flora | 2.5% (1) | 0.56 |
1–10 Days | 11–20 Days | >20 Days | |
---|---|---|---|
No of patients | 7 | 17 | 16 |
Deceased (n) | 3 | 1 | 1 |
Mean MAR index | 0.32 | 0.32 | 0.50 |
Mean FGSI | 7.14 | 4.35 | 4.31 |
3 antibiotics (n) | 4 | 13 | 12 |
Metronidazole (n) | 6 | 14 | 16 |
Carbapenems (n) | 3 | 12 | 5 |
Vancomycin (n) | 2 | 9 | 4 |
Fluoroquinolones(n) | 1 | 1 | 6 |
Cephalosporines (n) | 3 | 2 | 2 |
Piperacilin/Tazobactam (n) | 1 | 3 | 1 |
Gentamicin (n) | 1 | 1 | 0 |
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Puia, D.; Gheorghincă, Ş.; Pricop, C. The Antimicrobial Resistance Index and Fournier Gangrene Severity Index of Patients Diagnosed with Fournier’s Gangrene in a Tertiary Hospital in North Eastern Romania. Medicina 2023, 59, 643. https://doi.org/10.3390/medicina59040643
Puia D, Gheorghincă Ş, Pricop C. The Antimicrobial Resistance Index and Fournier Gangrene Severity Index of Patients Diagnosed with Fournier’s Gangrene in a Tertiary Hospital in North Eastern Romania. Medicina. 2023; 59(4):643. https://doi.org/10.3390/medicina59040643
Chicago/Turabian StylePuia, Dragoş, Ştefan Gheorghincă, and Cătălin Pricop. 2023. "The Antimicrobial Resistance Index and Fournier Gangrene Severity Index of Patients Diagnosed with Fournier’s Gangrene in a Tertiary Hospital in North Eastern Romania" Medicina 59, no. 4: 643. https://doi.org/10.3390/medicina59040643
APA StylePuia, D., Gheorghincă, Ş., & Pricop, C. (2023). The Antimicrobial Resistance Index and Fournier Gangrene Severity Index of Patients Diagnosed with Fournier’s Gangrene in a Tertiary Hospital in North Eastern Romania. Medicina, 59(4), 643. https://doi.org/10.3390/medicina59040643