Acute Coronary Syndrome Presenting during On- and Off-Hours: Is There a Difference in a Tertiary Cardiovascular Center?
Abstract
:1. Introduction
2. Materials and Methods
Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Variable | ON n = 848 | OFF n = 1025 | p Value |
---|---|---|---|
Age (years) | 63 ± 11 | 61 ± 10 | 0.241 |
Males n (%) | 475 (56) | 635 (62) | 0.011 |
Heredity n (%) | 296 (35) | 379 (37) | 0.266 |
Hypertension n (%) | 644 (76) | 738 (72) | 0.064 |
Diabetes mellitus n (%) | 203 (24) | 215 (21) | 0.087 |
Dyslipidemia n (%) | 390 (46) | 348 (34) | <0.001 |
PAD n (%) | 43 (5) | 45 (4) | 0.255 |
Smoking n (%) | 356 (42) | 474 (46) | 0.167 |
Previous MI n (%) | 250 (30) | 148 (14) | <0.001 |
Previous CVA n (%) | 41 (5) | 75 (7) | 0.033 |
Previous PCI n (%) | 128 (15) | 128 (12) | 0.124 |
Previous CABG n (%) | 40 (4) | 38 (4) | 0.451 |
BMI (kg/m2) | 29.3 ± 6.9 | 28.5 ± 7.4 | 0.554 |
LVEF (%) | 38.6 ± 11.3 | 37.8 ± 15.1 | 0.568 |
Variable | ON n = 848 | OFF n = 1025 | p Value |
---|---|---|---|
Unstable angina (%) | 99 (12) | 18 (2) | <0.001 |
STEMI n (%) | 585 (69) | 952 (93) | <0.001 |
NSTEMI n (%) | 164 (19) | 55 (5) | <0.001 |
CABG during hosp. n (%) | 7 (0.8) | 5 (0.5) | 0.263 |
No treatment n (%) | 127 (15) | 138 (13) | 0.187 |
Days in hospital (days) | 3.0 ± 2.6 | 3.6 ± 4.0 | 0.056 |
Maximum hs troponin (ng) | 41,789 ± 84,560 | 58,356 ± 62,079 | 0.050 |
Death during hosp. n (%) | 5 (0.6) | 14 (1.4) | 0.071 |
Variable | ON n = 848 | OFF n = 1025 | p Value |
---|---|---|---|
No significant disease n (%) | 174 (20) | 96 (9) | <0.001 |
Single vessel disease n (%) | 363 (43) | 536 (52) | <0.001 |
MVD n (%) | 485(57) | 489(48) | 0.006 |
* Vessels treated | |||
LAD n (%) | 327 (38) | 475(46) | 0.001 |
Cx n (%) | 228 (27) | 297 (29) | 0.256 |
RCA n (%) | 266 (31) | 538 (52) | <0.001 |
SVG n (%) | 21 (2) | 19 (2) | 0.506 |
Radial access n (%) | 692 (82) | 883 (86) | 0.004 |
Multivessel PCI n (%) | 187 (22) | 171 (16) | 0.002 |
LM PCI n (%) (ng) | 37 (4) | 35 (3) | 0.203 |
Bifurcation PCI n (%) | 110 (13) | 124 (12) | 0.409 |
More than one stent n (%) | 341 (41) | 352 (37) | 0.089 |
Stent diameter < 3.0 mm n (%) | 249 (29) | 276 (27) | 0.331 |
Variable | ON n = 848 | OFF n = 1025 | p Value |
---|---|---|---|
Death n (%) | 17 (2.0) | 26 (2.54) | 0.404 |
Myocardial infarction n (%) | 34 (4.0) | 17 (1.6) | 0.042 |
CVA n (%) | 0 (0) | 0 (0) | -------- |
Repeated PCI n (%) | 49 (5.8) | 27 (2.6) | 0.035 |
CABG n (%) | 5 (0.6) | 3 (0.4) | 0.524 |
MACCE n (%) | 105 (12.4) | 70 (6.8) | 0.039 |
Univariate | Multivariate | |||
---|---|---|---|---|
HR [95% CI] | p-Value | HR [95% CI] | p-Value | |
Age | 1.025 [1.004–1.048] | 0.021 | 1.024 [1.283–3.296] | 0.035 |
Male sex | 1.310 [0.820–2.090] | 0.258 | - - - | - - - |
Diabetes | 1.375 [0.792–2.386] | 0.258 | - - - | - - - |
LVEF | 0.994 [0.971–1.018] | 0.626 | - - - | - - - |
STEMI | 0.729 [0.405–1.312] | 0.292 | - - - | - - - |
Multivessel disease | 2.141 [1.339–3.423] | 0.001 | 2.056 [1.283–3.296] | 0.003 |
On hours admission | 1.755 [0.994–3.099] | 0.052 | 1.375 [0.992–2.386] | 0.258 |
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Ilic, I.; Radunovic, A.; Matic, M.; Zugic, V.; Ostojic, M.; Stanojlovic, M.; Kojic, D.; Boskovic, S.; Borzanovic, D.; Timcic, S.; et al. Acute Coronary Syndrome Presenting during On- and Off-Hours: Is There a Difference in a Tertiary Cardiovascular Center? Medicina 2023, 59, 1420. https://doi.org/10.3390/medicina59081420
Ilic I, Radunovic A, Matic M, Zugic V, Ostojic M, Stanojlovic M, Kojic D, Boskovic S, Borzanovic D, Timcic S, et al. Acute Coronary Syndrome Presenting during On- and Off-Hours: Is There a Difference in a Tertiary Cardiovascular Center? Medicina. 2023; 59(8):1420. https://doi.org/10.3390/medicina59081420
Chicago/Turabian StyleIlic, Ivan, Anja Radunovic, Milica Matic, Vasko Zugic, Miljana Ostojic, Milica Stanojlovic, Dejan Kojic, Srdjan Boskovic, Dusan Borzanovic, Stefan Timcic, and et al. 2023. "Acute Coronary Syndrome Presenting during On- and Off-Hours: Is There a Difference in a Tertiary Cardiovascular Center?" Medicina 59, no. 8: 1420. https://doi.org/10.3390/medicina59081420