Silver Diamine Fluoride Renaissance in Paediatric Dentistry: A 24-Month Retrospective and Cross-Sectional Analysis
Abstract
:1. Introduction
2. Materials and Methods
2.1. Ethical Approval and Study Outline
2.2. Retrospective Analysis
- Study sample and inclusion and exclusion criteria
- Clinical procedure
- Outcomes
2.3. Cross-Sectional Questionnaire-Based Analysis
- Sample size calculation
- Study participants
- Parents/caregivers
- Dental practitioners
2.4. Statistical Analysis
3. Results
3.1. Patient Profiles and Characteristics
3.2. Clinical Efficacy and Indication
3.3. Parents’ Acceptance and Satisfaction
3.4. Dentists’ Experience and Knowledge
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
- Butera, A.; Maiorani, C.; Morandini, A.; Simonini, M.; Morittu, S.; Trombini, J.; Scribante, A. Evaluation of Children Caries Risk Factors: A Narrative Review of Nutritional Aspects, Oral Hygiene Habits, and Bacterial Alterations. Children 2022, 9, 262. [Google Scholar] [CrossRef] [PubMed]
- Qasim, S.S.B.; Ali, D.; Khan, A.S.; Rehman, S.U.; Iqbal, A.; Baskaradoss, J.K. Evidence-Based Bibliometric Analysis of Research on Silver Diamine Fluoride Use in Dentistry. BioMed Res. Int. 2021, 2021, 9917408. [Google Scholar] [CrossRef] [PubMed]
- Schmoeckel, J.; Gorseta, K.; Splieth, C.H.; Juric, H. How to Intervene in the Caries Process: Early Childhood Caries—A Systematic Review. Caries Res. 2020, 54, 102–112. [Google Scholar] [CrossRef] [PubMed]
- BaniHani, A.; Santamaría, R.M.; Hu, S.; Maden, M.; Albadri, S. Minimal intervention dentistry for managing carious lesions into dentine in primary teeth: An umbrella review. Eur. Arch. Paediatr. Dent. 2022, 23, 667–693. [Google Scholar] [CrossRef] [PubMed]
- Santamaría, R.M.; Abudrya, M.H.; Gül, G.; Mourad, M.S.; Gomez, G.F.; Zandona, A.G.F. How to Intervene in the Caries Process: Dentin Caries in Primary Teeth. Caries Res. 2020, 54, 306–323. [Google Scholar] [CrossRef]
- World Health Organization. WHO Model List of Essential Medicines-22nd List, 2021; Technical Document; World Health Organization: Geneva, Switzerland, 2021. [Google Scholar]
- Chu, C.; Lo, E.; Lin, H. Effectiveness of silver diamine fluoride and sodium fluoride varnish in arresting dentin caries in Chinese pre-school children. J. Dent. Res. 2002, 81, 767–770. [Google Scholar] [CrossRef]
- dos Santos, V.E.; de Vasconcelos, F.M.; Ribeiro, A.G.; Rosenblatt, A. Paradigm shift in the effective treatment of caries in schoolchildren at risk. Int. Dent. J. 2012, 62, 47–51. [Google Scholar] [CrossRef]
- Nguyen, Y.H.T.; Ueno, M.; Zaitsu, T.; Nguyen, T.; Kawaguchi, Y. Caries Arresting Effect of Silver Diamine Fluoride in Vietnamese Preschool Children. Int. J. Clin. Prev. Dent. 2017, 13, 147–154. [Google Scholar] [CrossRef]
- Gao, S.S.; Amarquaye, G.; Arrow, P.; Bansal, K.; Bedi, R.; Campus, G.; Chen, K.J.; Chibinski, A.C.R.; Chinzorig, T.; Crystal, Y.O.; et al. Global Oral Health Policies and Guidelines: Using Silver Diamine Fluoride for Caries Control. Front. Oral Heal. 2021, 2, 685557. [Google Scholar] [CrossRef]
- Splieth, C.H.; Banerjee, A.; Bottenberg, P.; Breschi, L.; Campus, G.; Ekstrand, K.R.; Giacaman, R.A.; Haak, R.; Hannig, M.; Hickel, R.; et al. How to Intervene in the Caries Process in Children: A Joint ORCA and EFCD Expert Delphi Consensus Statement. Caries Res. 2020, 54, 297–305. [Google Scholar] [CrossRef]
- Al Masri, A.; Abudrya Mohamed, H.; Splieth, C.H.; Schmoeckel, J.; Mourad, M.S.; Santamaría, R.M. How did the COVID-19 pandemic lockdown affect dental emergency care in children? Retrospective study in a specialized pedodontic center. Quintessence Int. 2021, 52, 788–796. [Google Scholar] [CrossRef] [PubMed]
- Innes, N.P.T.; Stirrups, D.R.; Evans, D.J.P.; Hall, N.; Leggate, M. A novel technique using preformed metal crowns for managing carious primary molars in general practice—A retrospective analysis. Br. Dent. J. 2006, 200, 451–454. [Google Scholar] [CrossRef] [PubMed]
- Basner, R.; Santamaria, R.M.; Schmoeckel, J.; Schüler, E.; Splieth, C.H. Epidemiologische Begleituntersuchungen zur Gruppenprophylaxe 2016; DAJ-Deutsche Arbeitsgemeinschaft Für Jugendzahnpflege e. V: Bonn, Germany, 2018. [Google Scholar]
- Al-Eheideb, A.A.; Herman, N.G. Outcomes of dental procedures performed on children under general anesthesia. J. Clin. Pediatr. Dent. 2003, 27, 181–183. [Google Scholar] [CrossRef] [PubMed]
- Spera, A.L.; Saxen, M.A.; Yepes, J.F.; Jones, J.E.; Sanders, B.J. Office-Based Anesthesia: Safety and Outcomes in Pediatric Dental Patients. Anesth. Prog. 2017, 64, 144–152. [Google Scholar] [CrossRef]
- FDA Drug Safety Communication: FDA Review Results in New Warnings about Using General Anesthetics and Sedation Drugs in Young Children and Pregnant Women. 2016. Available online: https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-review-results-new-warnings-about-using-general-anesthetics-and (accessed on 11 September 2023).
- Phantumvanit, P.; Makino, Y.; Ogawa, H.; Rugg-Gunn, A.; Moynihan, P.; Petersen, P.E.; Evans, W.; Feldens, C.A.; Lo, E.; Khoshnevisan, M.H.; et al. WHO Global Consultation on Public Health Intervention against Early Childhood Caries. Community Dent. Oral Epidemiol. 2018, 46, 280–287. [Google Scholar] [CrossRef]
- Crystal, Y.O.; Marghalani, A.A.; Ureles, S.D.; Wright, J.T.; Sulyanto, R.; Divaris, K.; Fontana, M.; Graham, L. Use of silver diamine fluoride for dental caries management in children and adolescents, including those with special health care needs. Pediatr. Dent. 2017, 39, E135–E145. [Google Scholar] [CrossRef]
- Zaffarano, L.; Salerno, C.; Campus, G.; Cirio, S.; Balian, A.; Karanxha, L.; Cagetti, M.G. Silver Diamine Fluoride (SDF) Efficacy in Arresting Cavitated Caries Lesions in Primary Molars: A Systematic Review and Metanalysis. Int. J. Environ. Res. Public. Health 2022, 19, 12917. [Google Scholar] [CrossRef]
- Seifo, N.; Cassie, H.; Radford, J.R.; Innes, N.P.T. Silver diamine fluoride for managing carious lesions: An umbrella review. BMC Oral. Health 2019, 19, 145. [Google Scholar] [CrossRef]
- Chibinski, A.C.; Wambier, L.M.; Feltrin, J.; Loguercio, A.D.; Wambier, D.S.; Reis, A. Silver Diamine Fluoride Has Efficacy in Controlling Caries Progression in Primary Teeth: A Systematic Review and Meta-Analysis. Caries Res. 2017, 51, 527–541. [Google Scholar] [CrossRef]
- Gao, S.; Zhao, I.; Hiraishi, N.; Duangthip, D.; Mei, M.; Lo, E.; Chu, C. Clinical trials of silver diamine fluoride in arresting caries among children: A systematic review. JDR Clin. Transl. Res. 2016, 1, 201–210. [Google Scholar] [CrossRef]
- Crystal, Y.O.; Niederman, R. Evidence-Based Dentistry Update on Silver Diamine Fluoride. Dent. Clin. N. Am. 2019, 63, 45–68. [Google Scholar] [CrossRef] [PubMed]
- Seifo, N.; Robertson, M.; MacLean, J.; Blain, K.; Grosse, S.; Milne, R.; Seeballuck, C.; Innes, N. The use of silver diamine fluoride (SDF) in dental practice. Br. Dent. J. 2020, 228, 75–81. [Google Scholar] [CrossRef] [PubMed]
- Ballikaya, E.; Ünverdi, G.E.; Cehreli, Z.C. Management of initial carious lesions of hypomineralized molars (MIH) with silver diamine fluoride or silver-modified atraumatic restorative treatment (SMART): 1-year results of a prospective, randomized clinical trial. Clin. Oral Investig. 2022, 26, 2197–2205. [Google Scholar] [CrossRef] [PubMed]
- Zaeneldin, A.; Yu, O.Y.; Chu, C.-H. Effect of silver diamine fluoride on vital dental pulp: A systematic review. J. Dent. 2022, 119, 104066. [Google Scholar] [CrossRef] [PubMed]
- Seifo, N.; Cassie, H.; Radford, J.; Innes, N. “It’s really no more difficult than putting on fluoride varnish”: A qualitative exploration of dental professionals’ views of silver diamine fluoride for the management of carious lesions in children. BMC Oral. Health 2020, 20, 257. [Google Scholar] [CrossRef]
- Antonioni, M.B.; Fontana, M.; Salzmann, L.B.; Inglehart, M.R. Pediatric Dentists’ Silver Diamine Fluoride Education, Knowledge, Attitudes, and Professional Behavior: A National Survey. J. Dent. Educ. 2019, 83, 173–182. [Google Scholar] [CrossRef]
- Santamaria, R.M.; Innes, N.P.; Machiulskiene, V.; Evans, D.J.; Alkilzy, M.; Splieth, C.H. Acceptability of different caries management methods for primary molars in a RCT. Int. J. Paediatr. Dent. 2015, 25, 9–17. [Google Scholar] [CrossRef]
- Alajlan, G.; Alshaikh, H.; Alshamrani, L.; Alanezi, M.; Alarfaj, S.; AlSwayyed, T. Knowledge on and attitude toward silver diamine fluoride among Saudi dental practitioners in Riyadh public hospitals. Clin. Cosmet. Investig. Dent. 2020, 12, 399–407. [Google Scholar] [CrossRef]
- Vollú, A.L.; Moreira, J.P.d.L.; Luiz, R.R.; Barja-Fidalgo, F.; Fonseca-Gonçalves, A. Survey of knowledge, attitudes and practices of brazilian dentists regarding silver diamine fluoride. Pesqui. Bras. Odontopediatria Clin. Integr. 2019, 20, 1–7. [Google Scholar] [CrossRef]
- Magno, M.B.; da Silva, L.P.; Ferreira, D.M.; Barja-Fidalgo, F.; Fonseca-Gonçalves, A. Aesthetic perception, acceptability and satisfaction in the treatment of caries lesions with silver diamine fluoride: A scoping review. Int. J. Paediatr. Dent. 2019, 29, 257–266. [Google Scholar] [CrossRef]
- Clemens, J.; Gold, J.; Chaffin, J. Effect and acceptance of silver diamine fluoride treatment on dental caries in primary teeth. J. Public Health Dent. 2018, 78, 63–68. [Google Scholar] [CrossRef] [PubMed]
- Cernigliaro, D.; Kumar, A.; Northridge, M.E.; Wu, Y.; Troxel, A.B.; Cunha-Cruz, J.; Balzer, J.; Okuji, D.M. Caregiver satisfaction with interim silver diamine fluoride applications for their children with caries prior to operating room treatment or sedation. J. Public Health Dent. 2019, 79, 286–291. [Google Scholar] [CrossRef] [PubMed]
- Alshammari, A.F.; Almuqrin, A.A.; Aldakhil, A.M.; Alshammari, B.H.; Lopez, J.N.J. Parental perceptions and acceptance of silver diamine fluoride treatment in Kingdom of Saudi Arabia. Int. J. Health Sci. 2019, 13, 25–29. [Google Scholar]
- Vallittu, P.K.; Vallittu, A.S.J.; Lassila, V.P. Dental aesthetics—A survey of attitudes in different groups of patients. J. Dent. 1996, 24, 335–338. [Google Scholar] [CrossRef]
- Crystal, Y.O.; Janal, M.N.; Hamilton, D.S.; Niederman, R. Parental perceptions and acceptance of silver diamine fluoride staining. J. Am. Dent. Assoc. 2017, 148, 510–518.e4. [Google Scholar] [CrossRef]
- Butera, A.; Gallo, S.; Pascadopoli, M.; Montasser, M.A.; El Latief, M.H.A.; Modica, G.G.; Scribante, A. Home Oral Care with Biomimetic Hydroxyapatite vs. Conventional Fluoridated Toothpaste for the Remineralization and Desensitizing of White Spot Lesions: Randomized Clinical Trial. Int. J. Environ. Res. Public Health 2022, 19, 8676. [Google Scholar] [CrossRef]
Success |
Dental caries
|
Minor Failure |
Dental caries
|
Major Failure |
|
Characteristics (n = 93) | ||
---|---|---|
Age, mean (SD) | 5.3 years (2.9) | |
Gender, n (%) | Female | 45 (48.4) |
Male | 48 (51.6) | |
Caries experience, mean (SD) | d3mft | 6.3 (4.1) |
d3t | 4.9 (3.9) | |
D3MFT | 2.5 (3.7) | |
D3T | 1.6 (2.8) | |
Medical history, n (%) | Medically unfit | 13 (14) |
Medically fit | 80 (86) |
Outcomes n (%) | Treatments Performed | n (%) | |
---|---|---|---|
Success * 381 (85.2) | No restorative treatment performed 218 (57.2) | Further follow-ups ** | 218 (48.8) |
Further restorative treatment performed 163 (42.8) | SMART-Hall using PMC | 79 (17.6) | |
Filling (Composite/Compomer) | 50 (11.2) | ||
SMART-Technique with GIC | 22 (4.9) | ||
Anterior strip crowns | 12 (2.7) | ||
Minor Failure | Caries progression/Secondary caries 0 (0) | ||
Major Failure 66 (14.8) | Irreversible pulpitis/Abscess 66 (100) | Extraction | 55 (12.3) |
Pulpotomy | 11 (2.5) | ||
Total | 447 |
Questionnaire Item | n (%) | |
---|---|---|
Find SDF a good alternative to the treatment of early childhood caries. | Agree | 20 (74.1%) |
Somewhat agree | 3 (11.1%) | |
Neither | 3 (11.1%) | |
Somewhat disagree | 1 (3.7%) | |
Disagree | 0 (0%) | |
Prefer SDF over other options for the treatment early childhood caries. | Agree | 9 (33.3%) |
Somewhat agree | 9 (33.3%) | |
Neither | 8 (29.6%) | |
Somewhat disagree | 1 (3.7%) | |
Disagree | 0 (0%) | |
Use SDF treatment for anxious children with caries. | Agree | 10 (37%) |
Somewhat agree | 12 (44.4%) | |
Neither | 3 (11.1%) | |
Somewhat disagree Disagree | 0 (0%) 2 (7.4%) | |
Consider SDF before restorative therapy or general anesthesia. | Agree Somewhat agree Neither Somewhat disagree Disagree | 21 (77.8%) 5 (18.5%) 0 (0%) 1 (3.7%) 0 (0%) |
Confidently use SDF based on the researched evidence for its effectiveness. | Agree Somewhat agree Neither Somewhat disagree Disagree | 16 (59.3%) 9 (33.3%) 2 (7.4%) 0 (0%) 0 (0%) |
Had an experience with parents rejecting SDF treatment due to aesthetics. | Agree Somewhat agree | 1 (3.7%) 9 (33.3%) |
Neither | 6 (22.2%) | |
Somewhat disagree Disagree | 9 (33.3%) 2 (7.4%) |
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Abdulrahim, R.; Splieth, C.H.; Mourad, M.S.; Vielhauer, A.; Khole, M.R.; Santamaría, R.M. Silver Diamine Fluoride Renaissance in Paediatric Dentistry: A 24-Month Retrospective and Cross-Sectional Analysis. Medicina 2024, 60, 16. https://doi.org/10.3390/medicina60010016
Abdulrahim R, Splieth CH, Mourad MS, Vielhauer A, Khole MR, Santamaría RM. Silver Diamine Fluoride Renaissance in Paediatric Dentistry: A 24-Month Retrospective and Cross-Sectional Analysis. Medicina. 2024; 60(1):16. https://doi.org/10.3390/medicina60010016
Chicago/Turabian StyleAbdulrahim, Ruba, Christian H. Splieth, Mhd Said Mourad, Annina Vielhauer, Manasi R. Khole, and Ruth M. Santamaría. 2024. "Silver Diamine Fluoride Renaissance in Paediatric Dentistry: A 24-Month Retrospective and Cross-Sectional Analysis" Medicina 60, no. 1: 16. https://doi.org/10.3390/medicina60010016