Effectiveness and Complications of Bone Marrow Aspirate Concentrate in Patients with Knee Osteoarthritis of Kellgren–Lawrence Grades II–III
Abstract
:1. Introduction
2. Materials and Methods
BMAC Harvest and Injection Procedure
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Final Cohort | |
---|---|
Number of patients (knees) | 231 (285) |
Male:female | 59 (75):172 (210) |
Age (years) (mean ± SD) | 64.2 ± 7.5 |
Body mass index | 24.9 ± 3.2 |
K–L grades | |
II | 86 |
III | 199 |
Pretreatment | |
VAS pain score | 4.3 ± 4.2 |
Pretreatment | |
Knee Society knee score | 86.9 ± 7.9 |
Function score | 68.4 ± 14.2 |
1. Pretreatment | 2. PTD 1 Month | 3. PTD 3 Months | 4. PTD 6 Months | p-Value | Post Hoc | |
---|---|---|---|---|---|---|
VAS pain score | ||||||
All | 4.3 ± 4.2 | 1.5 ± 1.1 | 0.8 ±1.0 | 0.4 ± 0.6 | <0.05 | 1 > 2 > 3 = 4 |
K–L grade II | 4.0 ± 1.7 | 1.3 ± 1.0 | 0.5 ± 0.6 | 0.2 ± 0.4 | <0.05 | |
K–L grade III | 4.6 ± 5.5 | 1.7 ± 1.1 | 1.1 ± 1.1 | 0.5 ± 0.7 | <0.05 | |
KS knee score | ||||||
All | 86.9 ± 7.9 | 94.2 ± 3.8 | 96.7 ± 3.5 | 98.1 ± 2.7 | <0.05 | 4 > 3 > 2 > 1 |
K–L grade II | 87.1 ± 8.9 | 94.8 ± 3.7 | 97.8 ± 2.5 | 98.6 ± 2.2 | <0.05 | |
K–L grade III | 86.8 ± 7.0 | 93.8 ± 3.9 | 95.7 ± 4.0 | 97.7 ± 3.0 | <0.05 | |
KS function score | ||||||
All | 68.4 ± 14.2 | 74.9 ± 15.4 | 82.8 ± 13.6 | 83.3 ± 17.1 | <0.05 | 4 > 3 > 2 > 1 |
K–L grade II | 68.8 ± 15.4 | 76.1 ± 15.4 | 84.9 ± 11.9 | 85.7 ± 15.1 | <0.05 | |
K–L grade III | 68.0 ± 13.1 | 74.0 ± 15.4 | 81.0 ± 14.6 | 81.3 ± 18.5 | <0.05 |
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Baek, J.-H.; Lee, S.C.; Lee, D.N.; Ahn, H.S.; Nam, C.H. Effectiveness and Complications of Bone Marrow Aspirate Concentrate in Patients with Knee Osteoarthritis of Kellgren–Lawrence Grades II–III. Medicina 2024, 60, 977. https://doi.org/10.3390/medicina60060977
Baek J-H, Lee SC, Lee DN, Ahn HS, Nam CH. Effectiveness and Complications of Bone Marrow Aspirate Concentrate in Patients with Knee Osteoarthritis of Kellgren–Lawrence Grades II–III. Medicina. 2024; 60(6):977. https://doi.org/10.3390/medicina60060977
Chicago/Turabian StyleBaek, Ji-Hoon, Su Chan Lee, Dong Nyoung Lee, Hye Sun Ahn, and Chang Hyun Nam. 2024. "Effectiveness and Complications of Bone Marrow Aspirate Concentrate in Patients with Knee Osteoarthritis of Kellgren–Lawrence Grades II–III" Medicina 60, no. 6: 977. https://doi.org/10.3390/medicina60060977