Age as a Mortality Predictor in ECPR Patients
Abstract
:1. Introduction to ECPR in Modern Cardiac Care
2. Mortality Predictors in ECPR
3. The Specific Role of Age
4. ECPR Outcomes across Different Groups
5. Survival and Recovery across Age Groups
6. Balancing Clinical Decision-Making and Ethical Imperatives
7. Research Gaps and Future Directions
8. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Name of the Study | Number of Patients (Intervention/Control) | Mean Age of Randomized | Age—Inclusion Criteria | 30 Day CPC 1–2 in the Intervention Group |
---|---|---|---|---|
Prague OHCA [9] | 124/132 | 58 | 18–65 | 31% |
ARREST [10] | 15/15 | 59 | 18–75 | 21% |
INCEPTION [11] | 70/64 | 54 | 18–70 | 20% |
Study | Number of Patients | Inclusion Years | Main Conclusions |
---|---|---|---|
Miyamoto et al. [2] | 875 | 2014–2017 | Survival of 1.7% in older than 75; Less bystander CPR in the oldest group (29%, versus 51% in the youngest) |
Hsi-Yu Yu et al. [3] | 482 | 2006–2016 | Favorable neurological outcomes not statistically different between age groups—27%, 24%, and 18%, respectively, for groups 18–65, 66–75, 76 and more |
Inoue et al. [13] | 1644 | 2013–2018 | Patients up to 93 years old were cannulated; Favorable neurological outcome in 14% |
Kim et al. [6] | 318 | 2006–2018 | Patients 66 years and older had double mortality compared to the younger group |
Stub et al. [8] | 26 | Pre2013 | Median age 52; Survival with good neurological outcome 54% |
Goto et al. [14] | 144 | 2005–2013 | Worse survival in patients older than 70, OR 0.14 (95% CI, 0.03–0.8) |
Chahine et al. [15] | 391 | 2015–2023 | 30% higher mortality per every 10 years of age; Neurologically favorable survival 23% in the oldest group (70–79) |
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Spacek, R.; Weiss, V.; Kavalkova, P.; Jiravsky, O.; Barcak, J.; Belohlavek, J. Age as a Mortality Predictor in ECPR Patients. Medicina 2024, 60, 1444. https://doi.org/10.3390/medicina60091444
Spacek R, Weiss V, Kavalkova P, Jiravsky O, Barcak J, Belohlavek J. Age as a Mortality Predictor in ECPR Patients. Medicina. 2024; 60(9):1444. https://doi.org/10.3390/medicina60091444
Chicago/Turabian StyleSpacek, Radim, Vojtech Weiss, Petra Kavalkova, Otakar Jiravsky, Jan Barcak, and Jan Belohlavek. 2024. "Age as a Mortality Predictor in ECPR Patients" Medicina 60, no. 9: 1444. https://doi.org/10.3390/medicina60091444