Next Article in Journal
The Effect of Systemic Inflammation and Clinicopathologic Features on Survival in Malignant Pleural Mesothelioma: A Multicenter Analysis
Next Article in Special Issue
Editorial for the Special Issue “Infectious and Tropical Diseases: Symptoms, Diagnosis and Treatment”
Previous Article in Journal
Catastrophizing as a Predictor for Pain Perception and Disability Among Patients Undergoing Spinal Cord Stimulation
Previous Article in Special Issue
Tongue Tuberculosis as a Complication of Pott’s Disease in a Patient on Systemic Steroid Therapy without Pulmonary Tuberculosis
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Medicina
Volume 61
Issue 1
10.3390/medicina61010143
medicina-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Case Report

Hemoadsorption in Multiorgan Failure Due to Viscerocutaneous Loxoscelism

by
Raúl Valenzuela Córdova
1,2,
David Rivera Estrella
1,2,
José F. Bernardo
1,2,
Darío Jiménez
3,
Celia Rodríguez Tudero
4,5,
Raúl Elías
1,2 and
José C. De La Flor
6,7,8,*
1
Department of Nephrology, Hospital Nacional Cayetano Heredia, Lima 15002, Peru
2
Faculty of Medicine, Peruana Cayetano Heredia University, Lima 15002, Peru
3
Critical Nephrology Dialnef, Quito 170138, Ecuador
4
Department of Nephrology, Hospital Universitario de Salamanca, 37007 Salamanca, Spain
5
Surgery Doctoral Program, Faculty of Medicine, University of Salamanca, 37007 Salamanca, Spain
6
Department of Nephrology, Hospital Central de la Defensa Gómez Ulla, 28047 Madrid, Spain
7
Health Sciences Doctoral Program, Faculty of Medicine, Alcala University, 28805 Madrid, Spain
8
Department of Medicine and Medical Specialties, Faculty of Medicine, Alcala University, 28805 Madrid, Spain
*
Author to whom correspondence should be addressed.
Medicina 2025, 61(1), 143; https://doi.org/10.3390/medicina61010143
Submission received: 24 December 2024 / Revised: 2 January 2025 / Accepted: 14 January 2025 / Published: 16 January 2025
(This article belongs to the Special Issue Infectious and Tropical Diseases: Symptoms, Diagnosis and Treatment)
Browse Figure
Versions Notes

Abstract

Background: The bite of the Loxosceles spider is a public health problem around the world, mainly in Latin America. The viscerocutaneous presentation is related to the inoculation of toxins (phospholipase-D) that generates a systemic inflammatory reaction with a subsequent increase in cytokines and chemokines. Hemoadsorption is proposed as a therapy that allows for the removal of the toxin and modulation of the inflammatory response in this disease. Case Report: We present the case of a 31-year-old woman who was admitted to the hospital due to decreased urinary flow and jaundice 48 h after a spider bite. Despite treatment with intravenous (IV) monovalent antiloxoscelism serum, antibiotic therapy, and corticosteroids, the patient’s evolution was poor, and she was admitted to the critical care unit for severe multi-organ involvement, including hepatic and kidney damage and coagulation disorders, eventually requiring hemodialysis support and hemoadsorption therapy. After the therapy was administered, rapid improvement was evident with the suspension of vasopressor support and a decrease in inflammatory markers. Conclusions: This case presents hemoadsorption as a therapeutic option, based on its capacity to reduce the intensity of hyperinflammation and to regulate the immunological response.
Keywords: loxoscelism; hemoadsorption; viscerocutaneous loxoscelism loxoscelism; hemoadsorption; viscerocutaneous loxoscelism

Share and Cite

MDPI and ACS Style

Valenzuela Córdova, R.; Rivera Estrella, D.; Bernardo, J.F.; Jiménez, D.; Rodríguez Tudero, C.; Elías, R.; De La Flor, J.C. Hemoadsorption in Multiorgan Failure Due to Viscerocutaneous Loxoscelism. Medicina 2025, 61, 143. https://doi.org/10.3390/medicina61010143

AMA Style

Valenzuela Córdova R, Rivera Estrella D, Bernardo JF, Jiménez D, Rodríguez Tudero C, Elías R, De La Flor JC. Hemoadsorption in Multiorgan Failure Due to Viscerocutaneous Loxoscelism. Medicina. 2025; 61(1):143. https://doi.org/10.3390/medicina61010143

Chicago/Turabian Style

Valenzuela Córdova, Raúl, David Rivera Estrella, José F. Bernardo, Darío Jiménez, Celia Rodríguez Tudero, Raúl Elías, and José C. De La Flor. 2025. "Hemoadsorption in Multiorgan Failure Due to Viscerocutaneous Loxoscelism" Medicina 61, no. 1: 143. https://doi.org/10.3390/medicina61010143

APA Style

Valenzuela Córdova, R., Rivera Estrella, D., Bernardo, J. F., Jiménez, D., Rodríguez Tudero, C., Elías, R., & De La Flor, J. C. (2025). Hemoadsorption in Multiorgan Failure Due to Viscerocutaneous Loxoscelism. Medicina, 61(1), 143. https://doi.org/10.3390/medicina61010143

Article Metrics

Back to TopTop