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Marine Drugs, Volume 8, Issue 6

2010 June - 12 articles

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Articles (12)

  • Review
  • Open Access
189 Citations
20,008 Views
15 Pages

23 June 2010

Over billions of years, the ocean has been regarded as the origin of life on Earth. The ocean includes the largest range of habitats, hosting the most life-forms. Competition amongst microorganisms for space and nutrients in the marine environment is...

  • Review
  • Open Access
68 Citations
15,202 Views
27 Pages

Ecological and Physiological Studies of Gymnodinium catenatum in the Mexican Pacific: A Review

  • Christine J. Band-Schmidt,
  • José J. Bustillos-Guzmán,
  • David J. López-Cortés,
  • Ismael Gárate-Lizárraga,
  • Erick J. Núñez-Vázquez and
  • Francisco E. Hernández-Sandoval

23 June 2010

This review presents a detailed analysis of the state of knowledge of studies done in Mexico related to the dinoflagellate Gymnodinium catenatum, a paralytic toxin producer. This species was first reported in the Gulf of California in 1939; since the...

  • Article
  • Open Access
73 Citations
13,778 Views
12 Pages

21 June 2010

Eight marine cyanobacteria strains of the genera Cyanobium, Leptolyngbya, Oscillatoria, Phormidium, and Synechococcus were isolated from rocky beaches along the Atlantic Portuguese central coast and tested for ecotoxicity. Strains were identified by...

  • Review
  • Open Access
157 Citations
24,378 Views
70 Pages

Update on Methodologies Available for Ciguatoxin Determination: Perspectives to Confront the Onset of Ciguatera Fish Poisoning in Europe

  • Amandine Caillaud,
  • Pablo De la Iglesia,
  • H. Taiana Darius,
  • Serge Pauillac,
  • Katerina Aligizaki,
  • Santiago Fraga,
  • Mireille Chinain and
  • Jorge Diogène

14 June 2010

Ciguatera fish poisoning (CFP) occurs mainly when humans ingest finfish contaminated with ciguatoxins (CTXs). The complexity and variability of such toxins have made it difficult to develop reliable methods to routinely monitor CFP with specificity a...

  • Review
  • Open Access
75 Citations
14,559 Views
21 Pages

9 June 2010

Cyanobacteria of the genusLyngbya have proven to be prodigious producers of secondary metabolites. Many of these compounds are bioactive and show potential for therapeutic use. This review covers peptides and hybrid polyketide-non-ribosomal peptides...

  • Article
  • Open Access
23 Citations
11,930 Views
14 Pages

Intramolecular Modulation of Serine Protease Inhibitor Activity in a Marine Cyanobacterium with Antifeedant Properties

  • Susan Matthew,
  • Ranjala Ratnayake,
  • Mikel A. Becerro,
  • Raphael Ritson-Williams,
  • Valerie J. Paul and
  • Hendrik Luesch

4 June 2010

Extracts of the Floridian marine cyanobacterium Lyngbya cf. confervoides were found to deter feeding by reef fish and sea urchins (Diadema antillarum). This antifeedant activity may be a reflection of the secondary metabolite content, known to be com...

  • Review
  • Open Access
354 Citations
24,615 Views
24 Pages

3 June 2010

Many marine bacteria produce exopolysaccharides (EPS) as a strategy for growth, adhering to solid surfaces, and to survive adverse conditions. There is growing interest in isolating new EPS producing bacteria from marine environments, particularly fr...

  • Article
  • Open Access
16 Citations
11,209 Views
10 Pages

Evaluation of Pyridoacridine Alkaloids in a Zebrafish Phenotypic Assay

  • Xiaomei Wei,
  • Tim S. Bugni,
  • Mary Kay Harper,
  • Imelda T. Sandoval,
  • Elizabeth J. Manos,
  • Jennifer Swift,
  • Ryan M. Van Wagoner,
  • David A. Jones and
  • Chris M. Ireland

2 June 2010

Three new minor components, the pyridoacridine alkaloids 1-hydroxy-deoxyamphimedine (1), 3-hydroxy-deoxyamphimedine (2), debromopetrosamine (3), and three known compounds, amphimedine (4), neoamphimedine (5) and deoxyamphimedine (6), have been isolat...

  • Communication
  • Open Access
110 Citations
14,543 Views
6 Pages

Anti-Inflammatory Activity of Chitooligosaccharides in Vivo

  • João C. Fernandes,
  • Humberto Spindola,
  • Vanessa De Sousa,
  • Alice Santos-Silva,
  • Manuela E. Pintado,
  • Francisco Xavier Malcata and
  • João E. Carvalho

28 May 2010

All the reports to date on the anti-inflammatory activity of chitooligosaccharides (COS) are mostly based on in vitro methods. In this work, the anti-inflammatory activity of two COS mixtures is characterized in vivo (using balb/c mice), following th...

  • Article
  • Open Access
34 Citations
15,378 Views
12 Pages

In Situ Aquaculture Methods for Dysidea avara (Demospongiae, Porifera) in the Northwestern Mediterranean

  • Sonia De Caralt,
  • Javier Sánchez-Fontenla,
  • María J. Uriz and
  • Rene H. Wijffels

26 May 2010

Marine sponges produce secondary metabolites that can be used as a natural source for the design of new drugs and cosmetics. There is, however, a supply problem with these natural substances for research and eventual commercialisation of the products...

  • Article
  • Open Access
39 Citations
10,214 Views
7 Pages

Antibacterial Activities of a New Brominated Diterpene from Borneon Laurencia spp.

  • Charles Santhanaraju Vairappan,
  • Takahiro Ishii,
  • Tan Kai Lee,
  • Minoru Suzuki and
  • Zhan Zhaoqi

26 May 2010

In our continuous interest to study the diversity of halogenated metabolites of Malaysian species of the red algal genus Laurencia, we examined the chemical composition of five populations of unrecorded Laurencia sp. A new brominated diterpene, 10-ac...

  • Article
  • Open Access
77 Citations
16,541 Views
13 Pages

26 May 2010

The aim of this study was to first evaluate whether the chitosan hydrochloride-genipin crosslinking reaction is influenced by factors such as time, and polymer/genipin concentration, and second, to develop crosslinked drug loaded microspheres to impr...

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Mar. Drugs - ISSN 1660-3397