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Marine Drugs publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Marine Anti-Inflammatory and Antioxidant Agents, 4th Edition

edited by

Donatella Degl'Innocenti

and

Marzia Vasarri

submission deadline 30 Apr 2025 | 10 articles | Viewed by 14402 | Submission Open

Keywords: marine organisms; inflammation; cytokines; antioxidant agents; anti-inflammatory gents; oxidative stress; ROS/RNS; NF-κ B; mitochondrial oxidative; drug delivery

(This special issue belongs to the Section Marine Pharmacology)

Zebrafish Models in Marine Drug Discovery

edited by Xiaobin Li

submission deadline 30 Apr 2025 | 4 articles | Viewed by 6523 | Submission Open

Keywords: marine drugs; zebrafish model; active natural product; bioactivity screening; mechanism of action; activity evaluation

(This special issue belongs to the Section Marine Pharmacology)

Marine Natural Products with Immunomodulatory Activity

edited by

Emiliano Manzo

submission deadline 30 Apr 2025 | 2 articles | Viewed by 6354 | Submission Open

Keywords: marine natural products; drug discovery; immune system; immunomodulatory activity; immune activation; immune modulation; structural characterization; chemical synthesis

(This special issue belongs to the Section Marine Pharmacology)

Marine-Derived Bioactive Substances and Their Mechanisms of Action

edited by

Junsei Taira

submission deadline 30 Apr 2025 | 3 articles | Viewed by 6013 | Submission Open

Keywords: marine bioactive metabolite; antioxidant; anticancer; immunomodulatory action; cell signaling; mechanisms of action

(This special issue belongs to the Section Marine Pharmacology)

Marine-Derived Ingredients for Functional Foods

edited by

Constantina Nasopoulou

submission deadline 30 Apr 2025 | 4 articles | Viewed by 5170 | Submission Open

Keywords: marine-derived bioactive compounds; processing technologies; marine functional foods’ health benefits; functional food formulation; seaweeds

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Novel Marine Antimicrobial Agents: Isolation, Synthesis, and Biological Evaluation

edited by Shengrong Liao and

Haibo Zhang

submission deadline 30 Apr 2025 | 4 articles | Viewed by 3955 | Submission Open

Keywords: antimicrobial agent; marine compound; isolation; design & synthesis; antimicrobial activity; modification; marine origin; mechanism; marine organism; microbe

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Collection of Biosynthetic Genes from Marine Microbes

edited by

Hindra Hindra

submission deadline 30 Apr 2025 | 1 articles | Viewed by 2005 | Submission Open

Keywords: natural product; biosynthesis; genome mining; heterologous expression; metagenomics; feeding experiments

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Advances in Therapeutic Applications of Fish Oil, 2nd Edition

edited by

Cinzia Parolini

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1901 | Submission Open

Keywords: EPA; DHA; N-3 PUFA; marine-derived ingredients; nutraceutical; triglycerides; cardiovascular diseases; obesity; insulin resistance; metabolic syndrome

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Marine Bioactive Compounds for Skin Health

edited by

Hyun Soo Kim

submission deadline 30 Apr 2025 | 2 articles | Viewed by 1615 | Submission Open

Keywords: marine bioactive compounds; marine metabolites; skin health; skin inflammation; marine pharmaceuticals

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Marine Polysaccharides in Medical and Biotechnological Applications

edited by

Vincenzo Zammuto

Víctor L. Campos

and

Damiano Spagnuolo

submission deadline 30 Apr 2025 | 1 articles | Viewed by 631 | Submission Open

Keywords: antioxidant; antimicrobial; biomedical applications; biotechnology; bioremediation; polysaccharides; phycocolloids

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine Microalgae Culture and Active Substance Development

edited by

Jianke Huang

and

Zhen Zhang

submission deadline 30 Apr 2025 | Viewed by 464 | Submission Open

Keywords: marine microalgae; algal active substances; cultivation optimization; photobioreactor; pigments; PUFAs (polyunsaturated fatty acids); polysaccharides; separation and purification; efficacy evaluation

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Eutectic Solvents as Alternatives for Extracting Biologically Active Compounds from Marine Natural Products

edited by

Leslie Boudesocque-Delaye

and

Ana Rita Xavier De Jesus Gameiro

submission deadline 30 Apr 2025 | Viewed by 421 | Submission Open

Keywords: eutectic solvents; marine biomasses; nutraceutics; cosmetics; health; biorefinery; extraction processes; formulations processes; metabolite stabilization; by-product valorization

Marine Novel Secondary Metabolites and Potential Immunomodulatory Properties

edited by

Ji-Hye Ahn

submission deadline 30 Apr 2025 | Viewed by 152 | Submission Open

Keywords: marine secondary metabolites; immunomodulation; bioactive compounds; marine pharmacology; immune response; novel therapeutics; antioxidant properties; drug discovery; natural products

(This special issue belongs to the Section Marine Pharmacology)

Toxin–Antitoxin Systems in Marine Microbiology

edited by

Yunxue Guo

submission deadline 30 Apr 2025 | Viewed by 133 | Submission Open

Keywords: toxin– antitoxin systems; marine microbiology; regulation; application; mobile genetic elements

(This special issue belongs to the Section Marine Toxins)

Bioactive Compounds From Biofilm-Producing Marine Microorganisms

edited by

Weipeng Zhang

submission deadline 30 Apr 2025 | Viewed by 112 | Submission Open

Keywords: marine biofilms; microorganisms; pharmaceutical compounds; genomics; metabolomics

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine Natural Products as Anticancer Agents, 4th Edition

edited by

Celso Alves

and

Marc Diederich

submission deadline 15 May 2025 | 6 articles | Viewed by 6595 | Submission Open

Keywords: anticancer; anti-tumor; immune; molecular targets; co-cultures; 3D culture models; marine natural products; receptors; proteins; molecular modeling; chemical synthesis; immune-modulatory

(This special issue belongs to the Section Marine Pharmacology)

Marine-Derived Terpenes: Chemistry, Synthesis and Their Therapeutic Potential

edited by

Jinmei Xia

and Wenhai Xiao

submission deadline 15 May 2025 | 5 articles | Viewed by 6016 | Submission Open

Keywords: marine; terpene; structure elucidation; biosynthetic pathway; synthetic method; bioactivity; therapeutic application; anticancer; antimicrobial

(This special issue belongs to the Section Synthesis and Medicinal Chemistry of Marine Natural Products)

Celebrating the 100th Anniversary of Ocean University of China: Potential Therapeutic Benefits of Marine Novel Natural Products

edited by Peng Fu and

Chuanbin Shen

submission deadline 15 May 2025 | 2 articles | Viewed by 405 | Submission Open

Keywords: marine biotechnology; pharmacological profiling; marine anti-inflammatory agents; cancer therapeutics; infectious disease treatment; vascular disorder treatment; antithrombotic therapy; marine bioactive compounds; molecular targets; marine-derived therapeutics

(This special issue belongs to the Section Marine Pharmacology)

Marine Biotoxins 3.0

edited by

Jordi Molgó

submission deadline 31 May 2025 | 7 articles | Viewed by 12948 | Submission Open

Keywords: marine biotoxins; mechanism of action; pharmacology; cellular and molecular targets; signaling pathways; metabolism; toxicity; risk factors; molecular interactions; therapeutic potential

(This special issue belongs to the Section Marine Toxins)

Marine Natural Products with Anti-aging Activity

edited by Maria Elisa Giuliani and

Marco Malavolta

submission deadline 31 May 2025 | 4 articles | Viewed by 12305 | Submission Open

Keywords: aging; age-related diseases; longevity; healthspan; marine molecules; marine organisms; drug discovery

(This special issue belongs to the Section Marine Pharmacology)

Value-Added Products from Marine Fishes

edited by Helena Maria Lourenço and

Sónia Pedro

submission deadline 31 May 2025 | 5 articles | Viewed by 10145 | Submission Open

Keywords: marine fishes; bioactivity; health benefits; blue economy; chronic diseases

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Marine Proteins and Enzymes: Bioactivities and Medicinal Applications

edited by

Min-Jie Cao

and Asami Yoshida

submission deadline 31 May 2025 | 5 articles | Viewed by 9715 | Submission Open

Keywords: proteins; proteinases; glycolytic enzyme; enzymes; peptides; bioactive compounds; bioactivities; medicine

(This special issue belongs to the Section Marine Pharmacology)

Advances of Marine-Derived Enzymes

edited by

Olafur Fridjonsson

submission deadline 31 May 2025 | 8 articles | Viewed by 9581 | Submission Open

Keywords: marine enzymes; enzyme products; enzyme properties; exploitation potentials; marine biotechnology; biorefining; production technology

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Toxins as Marine-Based Drug Discovery, 2nd Edition

edited by

Steve Peigneur

submission deadline 31 May 2025 | 5 articles | Viewed by 7300 | Submission Open

Keywords: neurotoxins; marine natural compounds; sodium channels; potassium channels; calcium channels; chloride ion channels; TRP channels; ASIC channels; opiate receptors; acetylcholine receptors; NMDA receptors; antibiotics; antimicrobial peptides; gastropod venom peptides; sea anemone toxins

(This special issue belongs to the Section Marine Toxins)

Applications of Lipids from Marine Sources

edited by

Felisa Rey

and

Maria do Rosário Domingues

submission deadline 31 May 2025 | 3 articles | Viewed by 6761 | Submission Open

Keywords: lipidomics; marine organisms; functional foods; blue biotechnology; marine lipids

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

The Extraction and Application of Functional Components in Algae

edited by

Aurora Silva

Miguel Ángel Prieto Lage

Clara Grosso

and

Maria Fátima Sá Barroso

submission deadline 31 May 2025 | 3 articles | Viewed by 3668 | Submission Open

Keywords: algae functional components; extraction of bioactive molecules; health benefits; nutraceuticals; applications (food; pharmaceutical; wellness and care; etc.)

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Application of Marine Nature Products to Reduce Oxidative Stress

edited by

Chieh-Hsi Wu

submission deadline 31 May 2025 | 2 articles | Viewed by 3652 | Submission Open

Keywords: free radicals; inflammation; marine products; microbiota; system biology; signal transduction

(This special issue belongs to the Section Marine Pharmacology)

Fermentation Processes for Obtaining Marine Bioactive Products

edited by In Yung Sunwoo

submission deadline 31 May 2025 | 2 articles | Viewed by 2836 | Submission Open

Keywords: marine biomass; microorganism; fermentation; marine bioactive compounds; application

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Bioactive Metabolites Produced by Marine Cyanobacteria and Other Microalgae

edited by

Hanna Mazur-Marzec

and

Anna Toruńska-Sitarz

submission deadline 31 May 2025 | 1 articles | Viewed by 1674 | Submission Open

Keywords: cyanobacteria; microalgae; natural products; secondary metabolites; genome mining; extraction and isolation; structural analysis; biological activity; molecular targets; pharmaceutical application; biotechnological potential; toxicity

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine Sulfated Glycans

edited by

Yuefan Song

submission deadline 31 May 2025 | 1 articles | Viewed by 1064 | Submission Open

Keywords: marine sulfated glycans; glycosaminoglycan mimetics; algal glycans; fucoidans; bioactivity; biomedical application; biomaterial

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine Extremophiles: Adaptations and Biotechnological Applications

edited by

Sandra Pucciarelli

submission deadline 31 May 2025 | 1 articles | Viewed by 934 | Submission Open

Keywords: bioactive molecules; extremozymes; polar regions; extremophiles; biomaterials

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

New Methods in Extraction and Isolation of Marine Natural Products

edited by Débora Tomazi Pereira and Paz García-García

submission deadline 31 May 2025 | Viewed by 209 | Submission Open

Keywords: green extraction and isolation of marine natural products; marine extraction methods; isolation techniques; marine natural products; bioactive marine compounds; marine chemistry

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Bioactive Compounds from Marine Diatoms: Innovative Applications

edited by

Mostefa Fodil

submission deadline 31 May 2025 | Viewed by 137 | Submission Open

Keywords: marine diatoms; bioactive compounds; natural products; anticancer; anti-inflammatory; antimicrobial; antioxidants; biotechnology; marine biochemistry; drug discovery

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine Algae as Functional Foods

edited by Tânia Sofia Tavares

submission deadline 31 May 2025 | Viewed by 122 | Submission Open

Keywords: seaweed; bioactivity; extraction; sustainability; industry; food

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Marine Natural Products for Neglected Tropical Diseases

edited by Andre G. Tempone and João Henrique Ghilardi Lago

submission deadline 31 May 2025 | Viewed by 83 | Submission Open

Keywords: drug discovery; leishmaniasis; Chagas disease; African trypanosomiasis; marine microbiology; neglected diseases; marine compounds; antiviral; antimicrobial; antifungal

(This special issue belongs to the Section Marine Pharmacology)

Marine Biomaterials for Dental Applications

edited by Marcela R. Carrilho and Walter Antonio Bretz

submission deadline 31 May 2025 | Viewed by 76 | Submission Open

Keywords: marine products; marine biomimicry; functional biomaterials; dentistry; oral health

(This special issue belongs to the Section Biomaterials of Marine Origin)

High-Value-Added Resources Recovered from Marine By-Products

edited by Rong Cao and

Yongqiang Zhao

submission deadline 1 Jun 2025 | Viewed by 182 | Submission Open

Keywords: marine by-products; bioactive compounds; marine enzymes; nutraceuticals; peptide isolation; polysaccharide extraction; green extraction technologies; microbial fermentation; marine biomimetics

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Metabolic Regulation Functions and Mechanisms of Marine Bioactive Compounds

edited by

N. Liyanage

submission deadline 1 Jun 2025 | Viewed by 131 | Submission Open

Keywords: marine natural products; biological activity; compound isolation/characterization; marine extracts; drug discovery; therapeutic applications; human immunity; biomedical applications; anti-inflammatory; marine-based functional foods; metabolic disorders; metabolic pathways

(This special issue belongs to the Section Marine Pharmacology)

Marine Algal Biotechnology and Applications

edited by

Patrizia Casella

submission deadline 15 Jun 2025 | 4 articles | Viewed by 4024 | Submission Open

Keywords: microalgae; seaweed; alternative protein sources; fatty acids; high value compounds; biofuels; biomaterials; sustainability; circularity; biotechnologies

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Algal Cultivation for Obtaining High-Value Products, 2nd Edition

edited by

Cecilia Faraloni

and

Eleftherios Touloupakis

submission deadline 15 Jun 2025 | 2 articles | Viewed by 2528 | Submission Open

Keywords: algae; photosynthesis; antioxidant; stress; carotenoids; polyphenols; physiology; high-value product; photobioreactor; biotechnology; fatty acids

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Exploiting Marine ‘Omics’ Technologies for the Biodiscovery of Marine Natural Products

edited by

Stephen A. Jackson

submission deadline 15 Jun 2025 | 1 articles | Viewed by 2097 | Submission Open

Keywords: ‘ omics’ ; genomics; metagenomics; metabolomics; specialized/secondary metabolism biosynthetic gene clusters

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine Antiparasitic Agents, 2nd Edition

edited by

Carla Fernandes

, Anabela Cordeiro-da-Silva and Diana Resende

submission deadline 15 Jun 2025 | 1 articles | Viewed by 1328 | Submission Open

Keywords: antiparasitic; marine agents; safe extraction; green chemistry; parasites; helminths; protozoans

(This special issue belongs to the Section Marine Pharmacology)

Antimicrobial Compounds from Marine and Island Ecosystems: Exploration, Characterization, and Application

edited by

Ruoyu Mao

and Qingfen Guan

submission deadline 15 Jun 2025 | 1 articles | Viewed by 1010 | Submission Open

Keywords: marine and island ecosystems; antimicrobial compounds; immunomodulatory compounds; pharmaceuticals; nutraceuticals; mining; biotechnology; molecular structure; drug development

(This special issue belongs to the Section Marine Chemoecology for Drug Discovery)

Biosynthesis of Biologically Active Marine Natural Products 2025

edited by

Yiguang Zhu

submission deadline 15 Jun 2025 | Viewed by 409 | Submission Open

Keywords: marine microorganisms; marine plants and animals; genome mining; biosynthetic pathway enzymatic reaction mechanisms; marine bioactive compounds; structure elucidation; bioactivity screening; structure– activity relationship; pharmacological mechanism

Marine Brown Algae-Derived Bioactive Polysaccharide Fucoidans

edited by Hsien-Yeh Hsu

submission deadline 15 Jun 2025 | Viewed by 128 | Submission Open

Keywords: marine brown algae-derived fucoidan; polysaccharides; bioactivity; medical; fucoidan in human clinical trials; cosmetics; nutraceuticals; biotechnological

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Marine Biotoxins: Detection, Environmental Behaviour and Toxic Effects

edited by

Jiangbing Qiu

and

Yang Liu

submission deadline 15 Jun 2025 | Viewed by 75 | Submission Open

Keywords: marine biotoxins; phycotoxins; detection and analysis methods; environmental behaviours; toxicology and risk assessment

(This special issue belongs to the Section Marine Toxins)

Bioactive Molecules from Extreme Environments III

edited by

Daniela Giordano

submission deadline 30 Jun 2025 | 7 articles | Viewed by 23292 | Submission Open

Keywords: marine natural products; bioactive molecules; metabolites; anti-UV molecules; enzymes; peptides; extreme environments; polar regions; deep sea; hydrothermal vents; UV radiation

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Marine-Derived Biomaterials for Tissue Regeneration

edited by

Tiago H. Silva

and Gabriela S. Diogo

submission deadline 30 Jun 2025 | 6 articles | Viewed by 15278 | Submission Open

Keywords: polymers; polysaccharides; minerals; ceramics; marine biomaterials; customized biomaterials; tissue regeneration; collagen; chitin and chitosan; fish by-products

(This special issue belongs to the Section Biomaterials of Marine Origin)

Bioactive Natural Products from the Deep-Sea-Sourced Microbes

edited by

Bin-Gui Wang

and Siwen Niu

submission deadline 30 Jun 2025 | 9 articles | Viewed by 12059 | Submission Open

Keywords: deep-sea-sourced fungus; deep-sea-sourced actinomycetes; deep-sea-sourced bacteria; marine natural products; bioactive natural products; structure identification; antibacterial activity; antiviral activity; anti-inflammatory activity; cytotoxicity

(This special issue belongs to the Section Structural Studies on Marine Natural Products)

Marine Algae: Exploring Their Nutritional, Health, and Nutraceutical Potential

edited by

Leonel Pereira

and

Ana Marta Gonçalves

submission deadline 30 Jun 2025 | 6 articles | Viewed by 11924 | Submission Open

Keywords: seaweed; nutritional composition; health benefits; bioactive compounds; antioxidant properties; anti-inflammatory effects; anti-cancer potential; functional foods; dietary supplements; nutraceuticals; sustainability; extraction techniques; processing methods; human health

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

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