Body Composition in Women after Radical Mastectomy
Abstract
:1. Introduction
2. Materials and Methods
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Data Availability
Conflicts of Interest
References
- Miller, A.B. Early detection of breast cancer in the emerging world. Zent. Gynakol. 2006, 128, 191–195. [Google Scholar] [CrossRef]
- Smigal, C.; Jemal, A.; Ward, E.; Cokkinides, V.; Smith, R.; Howe, H.L.; Thun, M. Trends in breast cancer by race and ethnicity: Update 2006. CA Cancer J. Clin. 2006, 56, 168–183. [Google Scholar] [CrossRef] [Green Version]
- Matsuno, R.K.; Anderson, W.F.; Yamamoto, S.; Tsukuma, H.; Pfeiffer, R.M.; Kobayashi, K.; Devesa, S.S.; Levine, P.H. Early- and late-onset breast cancer types among women in the United States and Japan. Cancer Epidemiol. Biomark. Prev. 2007, 16, 1437–1442. [Google Scholar] [CrossRef] [Green Version]
- Garland, M.; Fang-Chi, H.; Clark, C.; Chiba, A.; Howard-McNatt, M. The impact of obesity on outcomes for patients undergoing mastectomy using the ACS-NSQIP data set. Breast Cancer Res. Treat. 2018, 168, 723–726. [Google Scholar] [CrossRef]
- Socha, M.; Bolanowski, M.; Jonak, W.; Górska-Kłęk, L.; Chwałczyńska, A.; Stanisławska, M. Total fatness and fatty tissue distribution in women after mastectomy. Endocrinol. Obes. Metab. Disord. 2008, 5, 7–12. [Google Scholar]
- Czerniak, U.; Demuth, A.; Skrzypczak, M. Associations of physical activity and inactivity with body tissue composition among healthy Polish women and women after mastectomy. Homo J. Comp. Hum. Biol. 2014, 65, 423–431. [Google Scholar] [CrossRef]
- Iyengar, N.M.; Morris, P.G.; Zhou, X.K.; Gucalp, A.; Giri, D.; Harbus, M.D.; Falcone, D.J.; Krasne, M.D.; Vahdat, L.T.; Subbaramaiah, K.; et al. Menopause is a determinant of breast adipose inflammation. Cancer Prev. Res. 2015, 8, 349–358. [Google Scholar] [CrossRef] [Green Version]
- Milewska, M.; Mioduszewska, M.; Pańczyk, M.; Kucharska, A. Two compartment model of body composition and abdominal fat area in postmenopausal women—pilot study. Med. News 2016, 69, 169–173. [Google Scholar]
- Leclerc, A.F.; Foidart-Dessalle, M.; Tomasella, M.; Coucke, P.; Devos, M.; Bruyère, O.; Bury, T.; Deflandre, D.; Jerusalem, G.; Lifrange, E.; et al. Multidisciplinary rehabilitation program after breast cancer: Benefits on physical function, anthropometry and quality of life. Eur. J. Phys. Rehabil. Med. 2017, 53, 633–642. [Google Scholar] [CrossRef] [PubMed]
- Artene, D.V.; Bordea, C.I.; Blidaru, A. Results of 1-year Diet and Exercise Interventions for ER+/PR±/HER2-Breast Cancer Patients Correlated with Treatment Type. Chirurgia 2017, 112, 457–468. [Google Scholar] [CrossRef]
- Fredslund, S.O.; Gravholt, C.H.; Laursen, B.E.; Jensen, A.B. Key metabolic parameters change significantly in early breast cancer survivors: An Explorative PILO Study. J. Transl. Med. 2019, 17, 105. [Google Scholar] [CrossRef]
- Iyengar, N.M.; Brown, K.A.; Zhou, X.K.; Gucalp, A.; Subbaramaiah, K.; Giri, D.D.; Zahid, H.; Bhardwaj, P.; Wendel, N.K.; Falcone, D.J.; et al. Metabolic obesity, adipose inflammation and elevated breast aromatase in women with normal body mass index. Cancer Prev. Res. 2017, 10, 235–243. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Carayol, M.; Ninot, G.; Senesse, P.; Bleuse, J.P.; Gourgou, S.; Sancho-Garnier, H.; Sari, H.; Romieu, I.; Romieu, G.; Jacot, W. Short- and long-term impact of adapted physical activity and diet counseling during adjuvant breast cancer therapy: The “APAD1” randomized controlled trial. BMC Cancer 2019, 19, 1–20. [Google Scholar] [CrossRef]
- Van den Berg, M.M.G.A.; Kok, D.E.; Posthuma, L.; Kamps, L.; Kelfkens, C.S.; Buist, N.; Geenen, M.; Haringhuizen, A.; Heijns, J.B.; van Lieshout, R.H.M.A.; et al. Body composition is associated with risk of toxicity-induced modifications of treatment in women with stage I-IIIB breast cancer receiving chemotherapy. Breast Cancer Res. Treat. 2019, 173, 475–481. [Google Scholar] [CrossRef] [Green Version]
- WHO. Waist Circumference and Wais-Hip Ratio, Report of a WHO Expert Consultation; WHO: Geneva, Switzerland, 2008; ISBN 978-92-4-150149-1. [Google Scholar]
- Demuth, A.; Czerniak, U. Overweight and obesity among adult women. J. Kinesiol. Exerc. Sci. 2009, 47, 59–63. [Google Scholar]
- Dutil, M.; Handrigan, G.A.; Corbeil, P.; Cantin, V.; Simoneau, M.; Teasdale, N.; Hue, O. The impact of obesity on balance control in community-dwelling older women. Age 2013, 35, 883–890. [Google Scholar] [CrossRef] [Green Version]
- Ostrowska, B.; Mraz, M. Body mass index and postural stability in older women with osteoporosis. Gerontol. Współczesna 2014, 2, 141–145. [Google Scholar]
- Kruk, J. Intensity of recreational physical activity in different life periods in relation to breast cancer among women in the region of Western Pomerania. Contemp. Oncol. 2012, 16, 576–581. [Google Scholar] [CrossRef]
- Ligibel, J.A.; Partridge, A.; Giobbie-Hurder, A.; Golshan, M.; Emmons, K.; Winer, E.P. Physical activity behaviors in women with newly diagnosed ductal carcinoma-in-situ in a longitudinal cohort study. Ann. Surg. Oncol. 2009, 16, 106–112. [Google Scholar] [CrossRef] [Green Version]
- Hsieh, C.; Sprod, L.K.; Hydock, D.S.; Carter, S.D.; Hayward, R.; Schneider, C.M. Effects of a Supervised Exercise Intervention on Recovery from Treatment Regimens in Breast Cancer Survivors. Oncol. Nurs. Forum. 2008, 35, 909–915. [Google Scholar] [CrossRef] [Green Version]
- Pierce, J.; Stefanick, M.; Flatt, S. Greater survival after breast cancer in physically active women with high vegetable-fruit intake regardless of obesity. J. Clin. Oncol. 2007, 17, 2345–2351. [Google Scholar] [CrossRef] [Green Version]
- Penttinen, H.M.; Saarto, T.; Kellokumpu-Lehtinen, P.; Blomqvist, C.; Huovinen, R.; Kautiainen, H.; Järvenpää, S.; Nikander, R.; Idman, I.; Luoto, R.; et al. Quality of life and physical performance and activity of breast cancer patients after adjuvant treatments. Psychooncology 2011, 20, 1211–1220. [Google Scholar] [CrossRef]
- Kabała, M.M.; Wilczyński, J. Obesity and postural stability in women after mastectomy. Med. Stud. 2019, 35, 48–54. [Google Scholar]
- Thomas, G.A.; Cartmel, B.; Harrigan, M.; Fiellin, M.; Capozza, S.; Zhou, Y.; Ercolano, E.; Gross, C.P.; Hershman, D.; Ligibel, J.; et al. The Effect of Exercise on Body Composition and Bone Mineral Density in Breast Cancer Survivors taking Aromatase Inhibitors. Obesity 2017, 25, 346–351. [Google Scholar] [CrossRef]
- Harvie, M. The importance of controlling body weight after a diagnosis of breast cancer: The role of diet and exercise in breast cancer patient management. In Exercise and Cancer Survivorship: Impact on Health Outcomes and Quality of Life; Saxton, J., Daley, A., Eds.; Springer: New York, NY, USA, 2010; pp. 73–96. [Google Scholar]
- Iyengar, N.M.; Gucalp, A.; Dannenberg, A.J.; Hudis, C.A. Obesity and cancer mechanisms: Tumor microenvironment and inflammation. J. Clin. Oncol. 2016, 34, 4270–4276. [Google Scholar] [CrossRef]
- Healy, L.A.; Ryan, A.M.; Carroll, P.; Ennis, D.; Crowley, V.; Boyle, T.; Kennedy, M.J.; Connolly, E.; Reynolds, J.V. Metabolic syndrome, central obesity and insulin resistance are associated with adverse pathological features in postmenopausal breast. Clin. Oncol. 2010, 22, 281–288. [Google Scholar] [CrossRef]
- Clarkson, P.M.; Kaufman, S.A. Should resistance exercise be recommended during breast cancer treatment? Med. Hypotheses 2010, 75, 192–195. [Google Scholar] [CrossRef]
- Gunter, M.J.; Xie, X.; Xue, X.; Kabat, G.C.; Rohan, T.E.; Wassertheil-Smoller, S.; Ho, G.Y.F.; Wylie-Rosett, J.; Greco, T.; Yu, H.; et al. Breast cancer risk in metabolically healthy but overweight postmenopausal women. Cancer Res. 2015, 75, 270–274. [Google Scholar] [CrossRef] [Green Version]
- Iyengar, N.M.; Arthur, R.; Manson, J.; Chlebowski, R.T.; Kroenke, C.H.; Peterson, L.; Cheng, T.Y.D.; Feliciano, E.C.; Lane, D.; Luo, J.; et al. Association of Body Fat and Risk of Breast Cancer in Postmenopausal Women with Normal Body Mass Index. JAMA Oncol. 2019, 5, 155–163. [Google Scholar] [CrossRef]
- Saad, F.; Adachi, J.D.; Brown, J.P.; Canning, L.A.; Gelmon, K.A.; Josse, R.G.; Pritchard, K.I. Cancer treatment-induced bone loss in breast and prostate cancer. J. Clin. Oncol. 2008, 26, 5465–5476. [Google Scholar] [CrossRef]
- Bardia, A.; Arieas, E.T.; Zhang, Z.; Defilippis, A.; Tarpinian, K.; Jeter, S.; Nguyen, A.; Henry, N.L.; Flockhart, D.A.; Hayes, D.F.; et al. Comparison of breast cancer recurrence risk and cardiovascular disease incidence risk among postmenopausal women with breast cancer. Breast Cancer Res. Treat. 2012, 131, 907–914. [Google Scholar] [CrossRef] [Green Version]
- Morris, P.G.; Hudis, C.A.; Giri, D.; Morrow, M.; Falcone, D.J.; Zhou, X.K.; Du, B.; Brogi, E.; Crawford, C.B.; Kopelovich, L.; et al. Inflammation and increased aromatase expression occur in the breast tissue of obese women with breast cancer. Cancer Prev. Res. 2011, 4, 1021–1029. [Google Scholar] [CrossRef] [Green Version]
- McTiernan, A.; Kooperberg, C.; White, E.; Wilcox, S.; Coates, R.; Adams-Campbell, L.L.; Woods, N.; Ockene, J. Recreational physical activity and the risk of breast cancer in postmenopausal women: The Women’s Health Initiative Cohort Study. JAMA 2003, 290, 1331–1336. [Google Scholar] [CrossRef]
- Chan, D.S.; Vieira, A.R.; Aune, D.; Bandera, E.V.; Greenwood, D.C.; McTiernan, A.; Rosenblatt, D.N.; Thune, I.; Vieira, R.; Norat, T. Body mass index and survival in women with breast cancer-systematic literature review and meta-analysis of 82 follow-up studies. Ann. Oncol. 2014, 25, 1901–1914. [Google Scholar] [CrossRef]
- Coin, A.; Giannini, S.; Minicuci, N.; Rinaldi, G.; Pedrazzoni, M.; Minisola, S.; Rossini, M.; Puente, A.D.; Inelmen, E.M.; Manzato, E.; et al. Limb fat-free mass and fat mass reference values by dual-energy X-ray absorptiometry (DEXA) in a 20–80 year-old Italian population. Clin. Nutr. 2012, 31, 506–511. [Google Scholar] [CrossRef]
- Gomes, P.R.L.; Freitas Junior, I.F.; Silva, C.B.; Gomes, I.C.; Rocha, A.P.R.; Salgado, A.S.I.; do Carmo, E.M. Short-term changes in handgrip strength, body composition, and lymphedema induced by breast cancer surgery. Rev. Bras. Ginecol. Obstet. 2014, 36, 244–250. [Google Scholar] [CrossRef] [Green Version]
- Vance, V.; Mourtzakis, M.; McCargar, L.; Hanning, R. Weight gain in breast cancer survivors: Prevalence, pattern and health consequences. Obes. Rev. 2011, 12, 282–294. [Google Scholar] [CrossRef]
- Van den Berg, M.M.G.A.; Winkels, R.M.; de Kruif, J.T.; van Laarhoven, H.W.M.; Visser, M.; de Vries, J.H.M.; de Vries, Y.C.; Kampman, E. Weight change during chemotherapy in breast cancer patients: A meta-analysis. BMC Cancer 2017, 17, 259. [Google Scholar] [CrossRef] [Green Version]
- Prokopowicz, K.; Kozdroń, E.; Prokopowicz, G.; Molik, B.; Berk, A.; Mucha, J. Conditions of physical activity undertaken by women after surgical breast cancer treatment. Hygeia Public Health 2018, 53, 100–105. [Google Scholar]
- Ridan, T.; Zdebska, S.; Ogrodzka, K.; Opuchlik, A. Evaluation of physical activity level in women after single breast mastectomy. Probl. Hyg. Epidemiol. 2015, 96, 181–186. [Google Scholar]
- Hashemi Bani, S.H.; Karimi, S.; Mahboobi, H. Lifestyle changes for prevention of breast cancer. Electron. Physician 2014, 3, 894–905. [Google Scholar]
- Irwin, M.L.; McTiernan, A.; Manson, J.E.; Thomson, C.A.; Sternfeld, B.; Stefanick, M.L.; Wactawski-Wende, J.; Craft, L.; Lane, D.; Martin, L.W.; et al. Physical activity and survival in postmenopausal women with breast cancer: Results from the women’s health initiative. Cancer Prev. Res. 2011, 4, 522–529. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Deluche, E.; Leobon, S.; Desport, J.C.; Venat-Bouvet, L.; Usseglio, J.; Tubiana-Mathieu, N. Impact of body composition on outcome in patients with early breast cancer. Support. Care Cancer 2018, 26, 861–868. [Google Scholar] [CrossRef]
- Brorson, H.; Ohlin, K.; Olsson, G.; Karlsson, M.K. Breast cancer-related chronic arm lymphedema is associated with excess adipose and muscle tissue. Lymphat Res. Biol. 2009, 7, 3–10. [Google Scholar] [CrossRef] [PubMed]
Variables | Descriptive Statistics of the Analysed Scales | Mann–Whitney U Test | |||||
---|---|---|---|---|---|---|---|
Group | X | SD | Min | Med | Max | ||
Age (years) | 1 | 55.07 | 4.71 | 45.00 | 55.50 | 60.00 | p = 0.001 |
2 | 50.27 | 5.13 | 45.00 | 49.00 | 60.00 | ||
Height (cm) | 1 | 163.03 | 4.49 | 152.00 | 164.00 | 173.00 | p = 0.622 |
2 | 162.40 | 4.76 | 152.00 | 164.00 | 176.00 | ||
Body mass (kg) | 1 | 73.01 | 12.93 | 46.50 | 69.75 | 104.50 | p = 0.021 |
2 | 65.95 | 11.21 | 49.90 | 62.30 | 92.90 | ||
Metabolic age | 1 | 51.00 | 13.04 | 29.00 | 50.00 | 83.00 | p = 0.001 |
2 | 39.83 | 10.73 | 27.00 | 34.00 | 63.00 | ||
BMI (kg/m2) | 1 | 27.56 | 5.32 | 18.20 | 26.65 | 40.10 | p = 0.049 |
2 | 24.96 | 3.73 | 18.60 | 24.40 | 32.80 | ||
Fat mass (%) | 1 | 34.03 | 8.96 | 13.50 | 33.55 | 66.50 | p = 0.007 |
2 | 29.16 | 8.58 | 14.00 | 27.65 | 60.20 | ||
Fat mass (kg) | 1 | 24.99 | 8.39 | 6.30 | 23.65 | 44.00 | p = 0.005 |
2 | 19.33 | 7.11 | 7.00 | 18.05 | 36.50 | ||
Fat-free mass (kg) | 1 | 48.59 | 5.57 | 40.20 | 47.80 | 60.50 | p = 0.224 |
2 | 46.96 | 5.38 | 39.70 | 45.70 | 62.40 | ||
Muscle mass (kg) | 1 | 47.00 | 6.78 | 38.10 | 46.30 | 69.60 | p = 0.109 |
2 | 43.97 | 6.29 | 24.50 | 43.40 | 59.30 | ||
Total body water (kg) | 1 | 34.42 | 3.97 | 28.30 | 33.85 | 43.00 | p = 0.236 |
2 | 33.37 | 3.85 | 28.00 | 32.45 | 44.40 | ||
Total body water (%) | 1 | 47.59 | 4.68 | 39.50 | 47.20 | 61.30 | p = 0.002 |
2 | 51.16 | 4.50 | 43.30 | 51.60 | 61.30 | ||
Muscle mass of left upper limb | 1 | 2.27 | 0.31 | 1.80 | 2.20 | 2.80 | p = 0.254 |
2 | 2.18 | 0.30 | 1.80 | 2.15 | 3.00 | ||
Muscle mass of right upper limb | 1 | 2.29 | 0.34 | 1.80 | 2.20 | 3.00 | p = 0.213 |
2 | 2.18 | 0.30 | 1.80 | 2.10 | 3.10 | ||
Fat mass of left upper limb | 1 | 1.54 | 0.77 | 0.20 | 1.30 | 3.50 | p = 0.013 |
2 | 1.09 | 0.52 | 0.30 | 1.00 | 2.20 | ||
Fat mass of upper right limb | 1 | 1.42 | 0.69 | 0.20 | 1.20 | 3.30 | p = 0.022 |
2 | 1.03 | 0.48 | 0.20 | 0.90 | 2.00 |
Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations. |
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Share and Cite
Wilczyński, J.; Sobolewski, P.; Zieliński, R.; Kabała, M. Body Composition in Women after Radical Mastectomy. Int. J. Environ. Res. Public Health 2020, 17, 8991. https://doi.org/10.3390/ijerph17238991
Wilczyński J, Sobolewski P, Zieliński R, Kabała M. Body Composition in Women after Radical Mastectomy. International Journal of Environmental Research and Public Health. 2020; 17(23):8991. https://doi.org/10.3390/ijerph17238991
Chicago/Turabian StyleWilczyński, Jacek, Piotr Sobolewski, Rafał Zieliński, and Magdalena Kabała. 2020. "Body Composition in Women after Radical Mastectomy" International Journal of Environmental Research and Public Health 17, no. 23: 8991. https://doi.org/10.3390/ijerph17238991