Prevalence of Oral Mucosal Diseases in Older Adults in Mainland China: A Meta-Analysis of Observational Studies
Abstract
:1. Introduction
2. Methods
2.1. Data Sources and Search Strategies
2.2. Study Eligibility
2.3. Data Extraction
2.4. Quality Assessment
2.5. Statistical Analyses
3. Results
3.1. Study Selection and Characteristics
3.2. Prevalence of Oral Mucosal Diseases, Subgroup and Meta-Regression Analyses
3.3. Quality Assessment and Publication Bias
4. Discussion
Author Contributions
Funding
Conflicts of Interest
References
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No. | First Author | Publication Year | Publication Language | Survey Year | Sampling | Sample Size | Male (N, %) | Urban (N, %) | Category of OMD | Number of OMD | Age (Mean ± SD) | Age Range | Province | Area | Quality Score | References |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Kang M. D. et al. | 1985 | CH | NR | No | 1949 | 754 (38.7) | 1531 (78.6) | WH, PM and others | 756 | NR | 60–104 | Henan | M | 2 | [14] |
2 | Xu K. L. et al. | 1985 | CH | 1983 | No | 50 | 12 (24.0) | 34 (68.0) | NR | 0 | 92.4 ± NR | 90–101 | Guangxi | E | 2 | [15] |
3 | Chen Y. N. | 1987 | CH | 1982 | No | 217 | 121 (55.8) | 217 (100) | EM, LK, WH, PM and others | 85 | NR | 60–87 | Zhejiang | E | 3 | [16] |
4 | Sun Y. et al. | 1987 | CH | NR | No | 284 | 263 (92.6) | 284 (100) | LP, WE, CG, XS and others | 105 | NR | ≥60 | Liaoning | E | 2 | [17] |
5 | Cao H. K. et al. | 1988 | CH | 1986 | No | 3091 | 1230 (39.8) | 3091 (100) | FT, KA, AG, RAU and others | 905 | NR | ≥60 | Shanghai | E | 3 | [18] |
6 | Chen X. et al. | 1989 | CH | 1987 | Yes | 205 | 145 (70.7) | 205 (100) | OS, FK, WE, FT and others | 69 | NR | ≥60 | Ningxia | W | 5 | [19] |
7 | Lin B. C. et al. | 1989 | CH | NR | Yes | 2191 | 1086 (49.6) | 2004 (91.5) | OS, FK, WE, FT and others | 981 | NR | ≥60 | Beijing | E | 6 | [20] |
8 | Mi C. F. et al. | 1991 | CH | 1989 | No | 496 | 391 (78.8) | 496 (100) | LK, LP, RAU, XS, OS | 247 | NR | ≥60 | Ningxia | W | 2 | [21] |
9 | Shen L.Y. | 1995 | CH | 1994 | No | 765 | 649 (84.8) | 765 (100) | LK, LP and others | 40 | NR | 60–75 | Jiangsu | E | 2 | [22] |
10 | Li Y. L. et al. | 1996 | CH | 1994–1995 | Yes | 344 | 256 (69.8) | 344 (100) | MH, LP, RAU and others | 89 | 67.48 ± NR | 60–77 | Inner Mongolia | M | 5 | [23] |
11 | Qiu H. S. et al. | 1996 | CH | NR | No | 105 | 77 (73.3) | 0 (0) | FT, LS, MP and others | 88 | NR | 100–135 | Xinjiang | W | 4 | [7] |
12 | Zhou X. J. | 2000 | CH | NR | No | 722 | NR | 769 (100) | OS, FT, WE and others | 408 | NR | ≥60 | Beijing | E | 3 | [24] |
13 | Lin H. C. et al. | 2001 | EN | 1997 | Yes | 1515 | 759 (50.1) | 774 (51.1) | LP, RAU, FT and others | 298 | NR | 65–74 | Guangdong | E | 6 | [25] |
14 | Liu Y. et al. | 2001 | CH | 1999 | No | 1872 | 785 (41.9) | 1872 (100) | FT, WE, LK, LP and others | 438 | 67.8 ± NR | 60–91 | Chongqing | E | 4 | [26] |
15 | Chen Q.Y. | 2006 | CH | NR | No | 800 | 400 (50.0) | NR | RAU, LP, LK and others | 173 | NR | 60–95 | Jiangsu | E | 2 | [27] |
16 | Chen X. H. et al. | 2007 | CH | 2003 | Yes | 1154 | 519 (45.0) | 1154 (100) | KA, LP, LK and others | 215 | NR | ≥60 | Guangdong | E | 5 | [28] |
17 | Liu H. et al. | 2009 | CH | 2007 | No | 108 | 54 (50.0) | NR | NR | 11 | NR | 65–70 | Xinjiang | W | 5 | [29] |
18 | Zhou H. J. et al. | 2009 | CH | 2005 | Yes | 791 | 391 (49.4) | 419 (53.0) | LK, LP and others | 61 | 68.0 ± NR | 65–74 | Gansu | W | 5 | [30] |
19 | Qian L. et al. | 2011 | CH | 2009–2011 | Yes | 435 | 135 (31.0) | 435 (100) | OC, SS, FT, KA and others | 189 | 79.22 ± NR | ≥60 | Jiangsu | E | 5 | [31] |
20 | Feng J. et al. | 2015 | EN | 2012–2013 | Yes | 3349 | NR | 3349 (100) | LK, LP, FT and others | 630 | NR | ≥60 | Shanghai | E | 5 | [10] |
21 | Zhang J. et al. | 2016 | CH | 2015–2016 | Yes | 1878 | 895 (47.7) | NR | LK, LP, and others | 136 | NR | 65–74 | Ningxia | W | 5 | [32] |
22 | Yin W. et al. | 2017 | EN | 2015–2016 | Yes | 744 | 362 (48.7) | 365 (49.1) | FT, RAU, LP and others | 61 | NR | 65–74 | Sichuan | W | 6 | [9] |
23 | Li Z. C. | 2017 | CH | 2015–2016 | Yes | 300 | 150 (50.0) | 150 (50.0) | NR | 0 | NR | 65–74 | Jiangxi | M | 6 | [8] |
24 | Zhang J.M. et al. | 2018 | CH | 2015–2016 | Yes | 288 | 144 (50.0) | NR | LK, LP and others | 16 | NR | 65–74 | Guangdong | E | 5 | [33] |
Category | Variables | Classification | Sample Size | Effect Size | 95% CI | I2 | p Across Subgroup | |
---|---|---|---|---|---|---|---|---|
Subgroup analysis | Region | East area (3) | 16,733 | 0.237 | 0.170 | 0.320 | 98.82 | 0.944 |
Middle area (4) | 2593 | 0.209 | 0.087 | 0.421 | 94.70 | |||
West area (1) | 4327 | 0.222 | 0.137 | 0.338 | 99.13 | |||
Publication language | EN (3) | 5608 | 0.147 | 0.071 | 0.281 | 95.97 | 0.155 | |
CN (21) | 18,045 | 0.247 | 0.191 | 0.312 | 98.78 | |||
Sampling | Yes (12) | 13,194 | 0.166 | 0.113 | 0.237 | 99.05 | 0.011 | |
No (12) | 10,459 | 0.310 | 0.223 | 0.413 | 98.41 |
Category | Variables | Slope | S.E. | 95% CI | t | p | |
---|---|---|---|---|---|---|---|
Meta-regression | Year of publication | −0.060 | 0.019 | −0.096 | −0.024 | −3.24 | 0.001 |
Survey year | −0.047 | 0.018 | −0.082 | −0.013 | −2.69 | 0.007 | |
Sample size | 0.0001 | 0.0003 | −0.0004 | 0.0006 | 0.53 | 0.599 | |
Study quality | −0.187 | 0.190 | −0.559 | 0.184 | −0.99 | 0.323 | |
Proportion of male | 0.020 | 0.016 | −0.011 | 0.052 | 1.28 | 0.199 | |
Proportion of urban | 0.002 | 0.010 | −0.019 | 0.022 | 0.15 | 0.880 |
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Zhou, N.; Zhang, X.; Yan, J.-Q.; Yu, Y.-Q.; Cai, Y. Prevalence of Oral Mucosal Diseases in Older Adults in Mainland China: A Meta-Analysis of Observational Studies. Int. J. Environ. Res. Public Health 2020, 17, 1887. https://doi.org/10.3390/ijerph17061887
Zhou N, Zhang X, Yan J-Q, Yu Y-Q, Cai Y. Prevalence of Oral Mucosal Diseases in Older Adults in Mainland China: A Meta-Analysis of Observational Studies. International Journal of Environmental Research and Public Health. 2020; 17(6):1887. https://doi.org/10.3390/ijerph17061887
Chicago/Turabian StyleZhou, Na, Xin Zhang, Jia-Qing Yan, Ya-Qin Yu, and Yan Cai. 2020. "Prevalence of Oral Mucosal Diseases in Older Adults in Mainland China: A Meta-Analysis of Observational Studies" International Journal of Environmental Research and Public Health 17, no. 6: 1887. https://doi.org/10.3390/ijerph17061887