Exposome and Social Vulnerability: An Overview of the Literature Review
Abstract
:1. Introduction
2. Material and Methods
2.1. Search Strategy
2.2. Studies Selection Strategy
- (i)
- The database PubMed, with the search date from January 2010 to August 2021 was used. This time frame was used to work with the most recent guidelines and policy framework regarding environmental issues as countries keep on changing their policies over time. This was performed to achieve homogeneity among the studies.
- (ii)
- The titles of articles and their abstracts were reviewed based on the inclusion and exclusion criteria.
- (iii)
- As a classical step, the reference list of the selected articles was also screened for possible additional articles.
- (iv)
- The initial search yielded 242 results. Thirty systematic review articles were retained to document the two different mechanisms known to explain the relation between socioeconomic status, nuisance, and health; namely, it is the differential of exposure and the social differential of vulnerability. This work aims to document only the second mechanism, as the first one has been already published.
- (v)
- Systematic reviews of 12 articles were retained solely for the work on exposome and social vulnerability.
- (vi)
- During the data extraction, one article was excluded as there is no quantitative result.
2.3. Study Selection
2.4. Data Extraction
3. Results
3.1. Studies Selected for Scoping Review
3.2. Overall Description
3.2.1. Social Conditions
3.2.2. Environmental Nuisances
3.2.3. The Social Exposome
4. Discussion
4.1. Main Findings
4.2. Limitations of the Review
4.3. Recommendations for Futures Studies
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Author and Date | Number of Studies | Population | Outcome | Location | Main Findings/Results | Limitations of the Study |
---|---|---|---|---|---|---|
Hibbert et al. (2019) | 146 studies | Children | Asthma, cardiovascular diseases, chronic conditions (general), diabetes and cancer | United States, Canada, and Europe | 1. Non-chemical stressors found in a child social environment can influence their health and wellbeing and influence their response to chemical exposure. 2. Adverse relationships exist between health and non-chemical stressors such as economic disadvantage, lower educational attainment, exposure to violence, adverse childhood experiences (ACE), stress, and urbanicity. 3. There is a salutary effect of non-chemical stressors such as exposure to or experience from green space and social support on health and well-being. | 1. Identification of numerous inconsistencies in terminology leading to heterogeneity. 2. Lack of interdisciplinary research to bridge the gap between physical and social sciences which could strengthen the designs and methodologies. 3. The possibility of not capturing all the studies in this review. |
Paterson et al. (2020) | 15 studies | Older people, infants, pregnant women and children (People) | Cardiorespiratory disease diabetes, mental health psychosocial problems | Ireland | 1. There is a heat-health vulnerability in Ireland and other temperate regions, especially among older people, chronically ill, infants, pregnant women, children, outdoor workers, socio-economically disadvantaged, urban dwellers thereby posing a public and occupational health challenge. 2. High and low temperatures were associated with adverse birth outcomes of preterm birth, low birth weight, and sometimes, stillbirth. 3. With heat and gender men are usually seen to be more vulnerable and suffer from heat than women. | Assessing mortality attributable to heat waves does not indicate the increased burden on the health sector from heat-related mortality. |
Wong et al. (2017) | Not available | Childhood, Adulthood (People) | Congenital heart diseases | Asia, Americas, Europe | 1. Stressors and toxic exposures during sensitive and critical periods of early development play critical roles in determining cardio metabolic risk over the life-course. 2. Interactions between maternal lifestyle factors that alter folate metabolism, such as obesity and carrier rates of certain genetic polymorphisms have been associated with increased risk of CHD. 3. Social antecedents play a significant role in conditioning disease burden and modulating outcomes of congenital heart disease. | N/A |
Gelormino et al. (2015) | 23 studies | People | Cardiovascular diseases, kidney diseases | America and Europe | 1. The natural environment, social context, and behaviors are all connected, partially or totally, to one of the following components: density and availability of public spaces and may influence individual health. | 1. There is heterogeneity among studies in the measurement of socio-economic status, the level of geographic aggregate considered, and the confounders accounted for. 2. Some of the studies used did not have the main objective of the research. 3. There is a lack of depth due to the absence of multi-disciplinarity. 4. The external validity of these studies is questionable, due to the significant effect of context, local research. |
Benmarhnia et al. (2015) | 61 studies | People | Mortality | Asia, Americas, Europe | 1. The strongest evidence of heat-related vulnerability was for the elderly ages >65 and >75 years and low SES groups (at the individual level), they were more vulnerable than their respective counterparts using the pooled estimates. | 1. Heterogeneity among studies, due to contrast definitions and other factors complicates the interpretation of a single summary estimate. 2. Several studies were excluded because the statistical heterogeneity test could not be performed. 3. The definition of vulnerability in this review was an epidemiological definition; however, vulnerability encompasses a social dimension. 4. In the literature reviewed in this article, vulnerability factors were considered separately but there are several modifying factors that might interact synergistically in the heat-related mortality relationship. |
Mathiarasan S et al. (2021) | Not available | Children | Neuropsychological health problems, respiratory diseases, sleep disorders and mental health issues. | Not available | 1. Air pollution disproportionately affects marginalized populations of lower socioeconomic status, children of lower socioeconomic status and are likely to be more exposed to both indoor and outdoor air pollution. | N/A |
Alderton et al. (2019) | 14 studies | Children (<8 years) and (>8 years) | Mental health | Europe and United States | Neighborhood built environment may be important for reducing mental health difficulties and increasing mental health competence among children. | There are gaps in the evidence hence there is the need to examine associations with positive aspects of mental health (mental health competence), the role of understudied neighborhood attributes like social infrastructure and service quality, and also different associations between the neighborhood-built environment and mental health in early years and the potential for modifications in the built environment to reduce health inequalities. |
Fuller et al. (2017) | 30 articles | People | Cardiovascular disease and mortality, hypertension, Ischemic heart disease, myocardial infarction | America, Europe, Asia, and Canada | 1. Adult never/former smokers are at a higher risk of incident asthma due to air pollution. 2. Children without atopy and children from low socio-economic status are at a higher risk of incident asthma due to air pollution. | 1. The use of identical measures across studies may not be appropriate across the board, for example, measures that capture SEP well for one population may not do so for another. 2. Area level measures of Socioeconomic position, proximal and distal factors that accumulate across the life course could modify air pollution associations with health and should be taken into consideration. 3. Large sample size is needed. 4. A full systematic review and meta-analysis were outside the scope of this review due to the heterogeneity of the exposure and outcome measures used. |
Burte et al. (2016) | 25 studies | Children and Adult (People) | Asthma | Canada, USA, Japan, Sweden | 1. Never/former smoker adults seem to be more susceptible to air pollution in relation to incident asthma. 2. Children without atopy seem to have a higher risk of incident asthma due to air pollution as well as children with low SES. 3. None of the studies included in the review was explicitly designed to assess the susceptibility factors concerning the associations between air pollution and incident asthma. | N/A |
Schule et al. (2015) | 33 studies | People | Depressive symptoms. | USA, Canada, Australia, New Zealand and Western European countries | 1. Independent association between characteristics of neighborhood SEP or the built environment and individual health outcomes or health-related behaviors. 2. Low neighborhood SES was independently associated with poor health, such as increased mortality r poor self-rated health, depressive symptoms, low birth weight, or cardiovascular risk factors. 3. The built environment has a significant impact on health outcomes. | N/A |
Erickson et al. (2014) | Not available | Pregnant women | Adverse pregnancy outcomes (early/recurrent miscarriages, hypertension, preeclampsia, fetal growth restriction, placenta abruption, pre-labour rapture of the fetal membranes (PROM) and spontaneous preterm labour), obesity, diabetes, cardiovascular and reproductive diseases. | Not available | Socioeconomic disparities are known to confound the environmental exposure effects, however, they may also act as potential effect modifiers given their overlapping etiological mechanisms with PM 2.5 exposure. |
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Deguen, S.; Amuzu, M.; Simoncic, V.; Kihal-Talantikite, W. Exposome and Social Vulnerability: An Overview of the Literature Review. Int. J. Environ. Res. Public Health 2022, 19, 3534. https://doi.org/10.3390/ijerph19063534
Deguen S, Amuzu M, Simoncic V, Kihal-Talantikite W. Exposome and Social Vulnerability: An Overview of the Literature Review. International Journal of Environmental Research and Public Health. 2022; 19(6):3534. https://doi.org/10.3390/ijerph19063534
Chicago/Turabian StyleDeguen, Séverine, Mary Amuzu, Valentin Simoncic, and Wahida Kihal-Talantikite. 2022. "Exposome and Social Vulnerability: An Overview of the Literature Review" International Journal of Environmental Research and Public Health 19, no. 6: 3534. https://doi.org/10.3390/ijerph19063534