Muscular Adaptations to Concurrent Resistance Training and High-Intensity Interval Training in Adults with Type 2 Diabetes: A Pilot Study
Abstract
:1. Introduction
2. Methods
2.1. Study Design and Population
2.2. Exercise Training
2.3. Assessment of Cardiovascular Risk Factors, Cardiorespiratory Fitness and Physical Activity Level
2.4. Muscle Mass and Quality
2.5. Muscle Performance
3. Statistical Analysis
4. Results
4.1. Baseline Measurements
4.2. Follow-Up Measurements
5. Discussion
6. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Variables | RT | RT + HIIT | p Values |
---|---|---|---|
Number of cases | 7 | 5 | - |
Age (years) | 55.9 ± 1.3 | 54.2 ± 1.6 | 0.438 |
Diabetes duration (years) | 4 (2; 12) | 2(1.7; 11) | 0.623 |
Body mass (kg) | 108 (86.2; 115.3) | 89.5 (85; 113) | 0.122 |
BMI (kg/m2) | 33.8 ± 3.6 | 31.8 ± 3.5 | 0.183 |
Fat mass (kg) | 35 ± 8.7 | 26 ± 8.9 | 0.048 |
Fat-free mass (kg) | 68.4 ± 8 | 71.2 ± 5.9 | 0.537 |
Waist circumference (cm) | 113.7 ± 11.9 | 110.1 ± 14.2 | 0.646 |
HbA1c (%) | 6.6 ± 1 | 6.4 ± 1.5 | 0.837 |
FPG (mg/dl) | 92.7 ± 29.8 | 114 ± 42.4 | 0.327 |
VO2max (mL/kg/min) | 22 ± 0.9 | 29.7 ± 0.4 | <0.001 |
Leg step-up (Kg) | 20.7 ± 5.7 | 16.5 ± 6.8 | 0.279 |
Leg extension (Kg) | 19.8 ± 8.1 | 40.8 ± 31.5 | 0.022 |
Lat pulldown | 58.7 ± 18.3 | 63.8 ± 7.4 | 0.358 |
Chest press (kg) | 37.7 ± 15.7 | 42.4 ± 10.6 | 0.383 |
Muscle power (W) | 328.4 ± 88.1 | 354.2 ± 40.3 | 0.559 |
Quadriceps volume (cm3) | 1.615 ± 328 | 1.691 ± 317.9 | 0.707 |
Leg extension muscle quality (kg/cm3) | 0.012 ± 0.003 | 0.026 ± 0.023 | 0.033 |
Leg step-up muscle quality (kg/cm3) | 0.011 ± 0.003 | 0.010 ± 0.004 | 0.298 |
Physical activity (min.d) | 0.670 | ||
Sedentary | 531 ± 33 | 501 ± 42 | 0.535 |
LPA | 293 ± 35 | 378 ± 49 | 0.129 |
MVPA | 23 ± 6 | 25 ± 3 | 0.459 |
RT | RT + HIIT | |||||
---|---|---|---|---|---|---|
Variables | Pre | Post | p Values | Pre | Post | p Values |
Isometric torque (Nm) | 143.2 ± 23.8 | 180.3 ± 54.8 | 0.060 | 209 ± 40.9 | 248.7 ± 39.3 | 0.204 |
Muscle power (W) | 328.4 ± 88.1 | 387.3 ± 94.2 | 0.021 | 354.2 ± 40.3 | 383.9 ± 26.7 | 0.037 |
Leg step-up (kg) | 20.7 ± 5.7 | 72.7 ± 6.7 | <0.001 | 16.5 ± 6.8 | 54.5 ± 32.9 | 0.083 |
Leg extension (kg) | 19.8 ± 8.1 | 32.1 ± 18.7 | 0.018 | 40.8 ± 31.5 | 50.4 ± 26.1 | 0.068 |
Lat pulldown (kg) | 58.7 ± 18.3 | 88 ± 23.9 | 0.005 | 63.8 ± 7.4 | 93.4 ± 11.5 | 0.003 |
Chest press (kg) | 37.7 ± 15.7 | 58 ± 29.2 | 0.041 | 42.4 ± 10.6 | 60.4 ± 25.2 | 0.103 |
Quadriceps volume (cm3) | 1.615 ± 328 | 1.701 ± 304 | 0.035 | 1.691 ± 317.9 | 1.778 ± 337.2 | 0.004 |
Leg extension muscle quality (kg/cm3) | 0.012 ± 0.003 | 0.019 ± 0.009 | 0.026 | 0.026 ± 0.023 | 0.030 ± 0.019 | 0.080 |
Leg step-up muscle quality (kg/cm3) | 0.011 ± 0.003 | 0.039 ± 0.005 | 0.002 | 0.010 ± 0.004 | 0.030 ± 0.009 | 0.072 |
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Orlando, G.; Pugh, J.; Faulkner, S.; Balducci, S.; Sacchetti, M.; Pugliese, G.; Bazzucchi, I.; Haxhi, J.; Martinez-Valdes, E.; Falla, D.; et al. Muscular Adaptations to Concurrent Resistance Training and High-Intensity Interval Training in Adults with Type 2 Diabetes: A Pilot Study. Int. J. Environ. Res. Public Health 2023, 20, 6746. https://doi.org/10.3390/ijerph20186746
Orlando G, Pugh J, Faulkner S, Balducci S, Sacchetti M, Pugliese G, Bazzucchi I, Haxhi J, Martinez-Valdes E, Falla D, et al. Muscular Adaptations to Concurrent Resistance Training and High-Intensity Interval Training in Adults with Type 2 Diabetes: A Pilot Study. International Journal of Environmental Research and Public Health. 2023; 20(18):6746. https://doi.org/10.3390/ijerph20186746
Chicago/Turabian StyleOrlando, Giorgio, Jamie Pugh, Steve Faulkner, Stefano Balducci, Massimo Sacchetti, Giuseppe Pugliese, Ilenia Bazzucchi, Jonida Haxhi, Eduardo Martinez-Valdes, Deborah Falla, and et al. 2023. "Muscular Adaptations to Concurrent Resistance Training and High-Intensity Interval Training in Adults with Type 2 Diabetes: A Pilot Study" International Journal of Environmental Research and Public Health 20, no. 18: 6746. https://doi.org/10.3390/ijerph20186746
APA StyleOrlando, G., Pugh, J., Faulkner, S., Balducci, S., Sacchetti, M., Pugliese, G., Bazzucchi, I., Haxhi, J., Martinez-Valdes, E., Falla, D., Manolopoulos, K., & Nimmo, M. A. (2023). Muscular Adaptations to Concurrent Resistance Training and High-Intensity Interval Training in Adults with Type 2 Diabetes: A Pilot Study. International Journal of Environmental Research and Public Health, 20(18), 6746. https://doi.org/10.3390/ijerph20186746