In recent years, although affected by the global economic slowdown, China’s import and consumption of crude oil have been rising due to the impact of new energy and the decline in international oil prices, as well as other adverse factors. China surpassed the United States in 2018 to become the world’s largest oil importer and the world’s second-largest oil consumer, according to the latest data. China imported about 500 million tons of crude oil in 2019, and its external dependence on crude oil reached a record high of 72%. In contrast, China’s crude oil production finally ended its negative growth in 2019, reaching 191 million tons. Therefore, China’s oil industry is still facing great pressure to increase and stabilize production. At the same time, affected by environmental change, how to reduce fossil fuel energy consumption is also a key consideration in the current development of oil. In order to balance the cost and benefit of exploitation and obtain greater economic benefits and recovery efficiency, oil fields adopt many methods, such as water flooding, hydrocarbon gas flooding, CO
2 flooding, and so on. Water flooding is the main way to enhance oil recovery at present. Multilayer commingled production can increase well production and oil recovery. Multilayer commingled production refers to an oilfield development method that utilizes the same pressure at the wellhead to develop each layer in a multilayer oil well. The overall cost of multilayer commingled production is low, and the process is easy to realize. However, there are some differences in the production and reserve utilization of each layer in the process of water flooding when the oil reservoir is heterogeneous. Significant fingering of the water–oil front will occur during the water flooding stage for a multilayer oil reservoir when the permeability contrast is relatively serious, which has a prominent effect on the recovery efficiency (Chai et al., 2021 [
1]; Salmo et al., 2021 [
2]; Schlueter et al., 2016 [
3]; Sorbie et al., 2020 [
4]). It is necessary to take into account the influence of reservoir heterogeneity on the development result when multilayer commingled production is carried out (Chai et al., 2022 [
5]; Cui et al., 2016 [
6]; Shen et al., 2018 [
7]; Xu et al., 2021 [
8]; Guo et al., 2022 [
9]; Tian et al., 2020 [
10]; Yang et al., 2022 [
11]). It is well known that there are some methods to investigate multilayer commingled production in oil reservoirs, and the main ways include physical simulation experiments (Fu et al., 2024 [
12]; Sun et al., 2019 [
13]; Huang et al., 2015 [
14]) and mathematical models (Kucuk et al., 1986 [
15]; Zhong et al., 2022 [
16]; Guo et al., 2010 [
17]). Xiong et al. (2005) designed three kinds of mathematical models of water flooding, including single-layer, two-layer, and three-layer heterogeneous models. The results showed that the production and utilization of the high-permeability layer were not affected by other layers, and the production and utilization of the middle- and low-permeability layers were determined by the gap [
18]. Mo et al. (2011) conducted experiments to study the utilization of each layer in production, contribution ratio, recovery efficiency, and other influencing factors. In addition, mathematical statistics were applied to analyze the relationship between effects and various influencing factors in water flooding. The results showed that the permeability stage difference limit of multilayer injection and production was between 8 and 15. The low-permeability layer could be better utilized when the value was less than eight, and it was difficult to use the low-permeability layer when the value was greater than 15 [
19]. Deng et al. (2022) designed a multi-pipe parallel waterflooding experiment and studied the effects of permeability area, water cut, pressure difference, and crude oil viscosity on the combined production in multiple zones. The findings indicate that there is less interference and a weaker difference in the physical characteristics of the layers, the smaller the permeability range. By reducing the water content between layers, interference between layers can be effectively reduced. Increasing the pressure difference can improve the oil displacement efficiency [
20]. Fu et al. (2024) created a visual sand-filled pipe experiment model, simulated the oil–water two-phase flow process, and revealed the influencing factors of water-driven oil flow through microscopic flow simulation. The results show that the higher the permeability, the stronger the microheterogeneity, and the lower the overall mobility increase after flooding. The adaptation coefficient increases with increasing drive pressure difference for a given permeability. In multizone combination production, interzone interference occurs, and the greater the interzone difference, the higher the initial production capacity of the combined production well [
12]. However, the high-permeability layer is easy to flood, resulting in ineffective water circulation, and the low-permeability pipe is difficult to flood completely, resulting in a slight increase in overall mobility. Through microscopic flow simulation, Li created a visual sand-filled pipe experiment model, simulated the oil–water two-phase flow process, and revealed the influencing factors of water-driven oil flow. The results show that the higher the permeability, the stronger the microheterogeneity, and the lower the overall mobility increases after flooding. The adaptation coefficient increases with increasing drive pressure difference for a given permeability. Combined production in multiple zones involves interzonal interference, and the greater the interzonal difference, the higher the initial production capacity of combined production. Tariq et al. (1978) developed a new model of multilayer commingled production in oil reservoirs, and a numerical inversion method was used to evaluate the analytical solution of the layered system problem in Laplace space. The results showed that false wellbore storage effects would appear in cases involving high-permeability contrast and a small, highly permeable layer. Also, it was found that there were two semi-log permeable layers. It was found that layered system data could be analyzed under certain circumstances to yield information about the permeability ratio and the radius of the layers [
21]. Tompang et al. (1988) developed a five-bed linear model to investigate the effect of crossflow on water flooding in a stratified reservoir. The results showed that the oil recovery and crossflow index were dependent on the value of RL (effective length-to-height ratio) for favorable mobility ratios and on the value of RD (vertical-to-horizontal pressure gradients ratio) for unfavorable mobility ratios [
22]. Based on the theory of oil–water two-phase unstable flow, Cui et al. (2016) established a mathematical model of multilayer combined production in water-drive reservoirs. The model takes into account interlayer differences such as permeability, oil viscosity, and remaining oil saturation. The results show that the pseudo-current resistance contrast should be less than four in layered single sampling. The model was applied to the Shengtuo oilfield, and the recovery rate increased by 6.08% [
6]. Sheng et al. (2018) established a one-dimensional linear flow model and a plane radial flow model for multilayer commingled production using the Buckley–Leverett theory. The parameters, such as seepage resistance, sweep efficiency, and recovery efficiency, can be accurately evaluated by this model. The results show that the difference in seepage resistance is an important factor affecting the recovery efficiency of multilayer commingled production. When the permeability range reaches a certain value, fractional extraction must be undertaken [
7]. Xu et al. (2021) used the Fedassi, Buckley–Leverett, and material balance equations to build the percolation model of multilayer commingled production with water displacement. The model was then solved using the iteration method, considering saturation, bottom flow pressure, microelement of the borehole, and oil–water relative permeability. By contrasting the model’s output with that of a standard black oil model, the model’s accuracy was confirmed [
8]. Wang et al. (2023) built a mathematical model of multilayer commingled production in oil reservoirs. The simulated results demonstrated that such a validated mathematical model had been upscaled and used to precisely evaluate and forecast the dynamic co-production characteristics of a real multilayer reservoir, with overall deviations of 2.36 percent and 5.50 percent for oil production and water cut, respectively [
23]. In the research process, boundary calculations are typically based on experimental data rather than theoretical models. This study focuses on exploring the permeability differential limit in water flood development within multilayer commingled production reservoirs. Initially, indoor core parallel physical simulation experiments were conducted. Through the establishment of a theoretical mathematical model and iterative solution using B-L theory, the variation in liquid production for each layer prior to water breakthrough in low-permeability layers was calculated. Additionally, the changes in recovery degree for each layer and the production contribution rate at different stages were examined. By cross-referencing the results of these analyses, the maximum permissible permeability difference in water drive multilayer commingled production reservoirs was determined. This information is vital in determining appropriate layer divisions and selecting the best development strategies for subsequent layer adjustments.