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Review

Cutting-Edge Hydrogel Technologies in Tissue Engineering and Biosensing: An Updated Review

by
Nargish Parvin
,
Vineet Kumar
,
Sang Woo Joo
* and
Tapas Kumar Mandal
*
School of Mechanical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea
*
Authors to whom correspondence should be addressed.
These authors contributed equally to this work.
Materials 2024, 17(19), 4792; https://doi.org/10.3390/ma17194792 (registering DOI)
Submission received: 16 August 2024 / Revised: 22 September 2024 / Accepted: 26 September 2024 / Published: 29 September 2024
(This article belongs to the Special Issue Advanced Composite Biomaterials for Tissue Regeneration)

Abstract

Hydrogels, known for their unique ability to retain large amounts of water, have emerged as pivotal materials in both tissue engineering and biosensing applications. This review provides an updated and comprehensive examination of cutting-edge hydrogel technologies and their multifaceted roles in these fields. Initially, the chemical composition and intrinsic properties of both natural and synthetic hydrogels are discussed, highlighting their biocompatibility and biodegradability. The manuscript then probes into innovative scaffold designs and fabrication techniques such as 3D printing, electrospinning, and self-assembly methods, emphasizing their applications in regenerating bone, cartilage, skin, and neural tissues. In the realm of biosensing, hydrogels’ responsive nature is explored through their integration into optical, electrochemical, and piezoelectric sensors. These sensors are instrumental in medical diagnostics for glucose monitoring, pathogen detection, and biomarker identification, as well as in environmental and industrial applications like pollution and food quality monitoring. Furthermore, the review explores cross-disciplinary innovations, including the use of hydrogels in wearable devices, and hybrid systems, and their potential in personalized medicine. By addressing current challenges and future directions, this review aims to underscore the transformative impact of hydrogel technologies in advancing healthcare and industrial practices, thereby providing a vital resource for researchers and practitioners in the field.
Keywords: hydrogel technologies; tissue engineering applications; biosensing innovations; 3D printing hydrogels; wearable health devices hydrogel technologies; tissue engineering applications; biosensing innovations; 3D printing hydrogels; wearable health devices

Graphical Abstract

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MDPI and ACS Style

Parvin, N.; Kumar, V.; Joo, S.W.; Mandal, T.K. Cutting-Edge Hydrogel Technologies in Tissue Engineering and Biosensing: An Updated Review. Materials 2024, 17, 4792. https://doi.org/10.3390/ma17194792

AMA Style

Parvin N, Kumar V, Joo SW, Mandal TK. Cutting-Edge Hydrogel Technologies in Tissue Engineering and Biosensing: An Updated Review. Materials. 2024; 17(19):4792. https://doi.org/10.3390/ma17194792

Chicago/Turabian Style

Parvin, Nargish, Vineet Kumar, Sang Woo Joo, and Tapas Kumar Mandal. 2024. "Cutting-Edge Hydrogel Technologies in Tissue Engineering and Biosensing: An Updated Review" Materials 17, no. 19: 4792. https://doi.org/10.3390/ma17194792

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