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Open AccessArticle
Effect of Er,Cr:YSGG Laser Irradiation on the Surface Modification and Cell Adhesion on Titanium Discs: An In Vitro Study
by
Takahiko Shiba
Takahiko Shiba ,
Kailing Ho
Kailing Ho ,
Xuehao Ma
Xuehao Ma ,
Ye Won Cho
Ye Won Cho ,
Chia-Yu Chen
Chia-Yu Chen and
David M. Kim
David M. Kim *
Division of Periodontology, Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA 02115, USA
*
Author to whom correspondence should be addressed.
Materials 2024, 17(19), 4899; https://doi.org/10.3390/ma17194899 (registering DOI)
Submission received: 25 July 2024
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Revised: 20 August 2024
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Accepted: 29 September 2024
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Published: 6 October 2024
Abstract
This study evaluates the potential of erbium, chromium-doped:yttrium, scandium, gallium, and garnet (Er,Cr:YSGG) laser irradiation to modify the titanium surface for optimal seeding of fibroblasts and osteoblasts in the treatment of peri-implantitis. Titanium discs were treated using the Er,Cr:YSGG laser, an ultrasonic device with a stainless tip, or titanium scalers. Changes in surface properties were analyzed by profilometer and scanning electron microscopy (SEM). Murine fibroblast and osteoblast adhesion and proliferation were evaluated qualitatively and quantitatively at 24 and 72 h. Profilometric surface topography and SEM showed that titanium scalers and ultrasonic debridement techniques significantly changed the structure of the machined and rough titanium surfaces. The Er,Cr:YSGG laser irradiation, on the other hand, did not alter titanium microstructures. The Er,Cr:YSGG laser irradiation with the 40 Hz group showed a significantly higher attached fibroblast cell numbers than the titanium scaler group at 72 h after treatment (p = 0.023). Additionally, the number of the attached osteoblasts in the Er,Cr:YSGG laser irradiation with the 40 Hz group was significantly higher than that of the no-treatment groups 24 h after treatment (p = 0.045). The Er,Cr:YSGG laser effectively promoted adherence of fibroblasts and osteoblasts to the titanium surface without significantly altering the titanium surface, suggesting its superiority for treating peri-implantitis.
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MDPI and ACS Style
Shiba, T.; Ho, K.; Ma, X.; Cho, Y.W.; Chen, C.-Y.; Kim, D.M.
Effect of Er,Cr:YSGG Laser Irradiation on the Surface Modification and Cell Adhesion on Titanium Discs: An In Vitro Study. Materials 2024, 17, 4899.
https://doi.org/10.3390/ma17194899
AMA Style
Shiba T, Ho K, Ma X, Cho YW, Chen C-Y, Kim DM.
Effect of Er,Cr:YSGG Laser Irradiation on the Surface Modification and Cell Adhesion on Titanium Discs: An In Vitro Study. Materials. 2024; 17(19):4899.
https://doi.org/10.3390/ma17194899
Chicago/Turabian Style
Shiba, Takahiko, Kailing Ho, Xuehao Ma, Ye Won Cho, Chia-Yu Chen, and David M. Kim.
2024. "Effect of Er,Cr:YSGG Laser Irradiation on the Surface Modification and Cell Adhesion on Titanium Discs: An In Vitro Study" Materials 17, no. 19: 4899.
https://doi.org/10.3390/ma17194899
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