Optimization of a Modular Nanotransporter Design for Targeted Intracellular Delivery of Photosensitizer
Abstract
:1. Introduction
2. Materials and Methods
2.1. Cell Lines
2.2. Producing MNTs with a Truncated Carrier Module
2.3. MNT Expression and Purification
2.4. Binding Assay
2.5. Liposome Leakage Assay
2.6. Thermophoresis
2.7. Photocytotoxicity
3. Results
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Alieva, R.T.; Ulasov, A.V.; Khramtsov, Y.V.; Slastnikova, T.A.; Lupanova, T.N.; Gribova, M.A.; Georgiev, G.P.; Rosenkranz, A.A. Optimization of a Modular Nanotransporter Design for Targeted Intracellular Delivery of Photosensitizer. Pharmaceutics 2024, 16, 1083. https://doi.org/10.3390/pharmaceutics16081083
Alieva RT, Ulasov AV, Khramtsov YV, Slastnikova TA, Lupanova TN, Gribova MA, Georgiev GP, Rosenkranz AA. Optimization of a Modular Nanotransporter Design for Targeted Intracellular Delivery of Photosensitizer. Pharmaceutics. 2024; 16(8):1083. https://doi.org/10.3390/pharmaceutics16081083
Chicago/Turabian StyleAlieva, Rena T., Alexey V. Ulasov, Yuri V. Khramtsov, Tatiana A. Slastnikova, Tatiana N. Lupanova, Maria A. Gribova, Georgii P. Georgiev, and Andrey A. Rosenkranz. 2024. "Optimization of a Modular Nanotransporter Design for Targeted Intracellular Delivery of Photosensitizer" Pharmaceutics 16, no. 8: 1083. https://doi.org/10.3390/pharmaceutics16081083