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Neurology International
Volume 1
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10.4081/ni.2009.e15
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Neurology International is published by MDPI from Volume 12 Issue 3 (2020). Previous articles were published by another publisher in Open Access under a CC-BY licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Article

Mills’ Syndrome: A Case Report

by
Fábio Henrique de Gobbi Porto
1,
Marco Orsini
1,2,
Marco Antônio Araújo Leite
1,2,
José Moreira dos Santos
1,
Soraia Pulier
1,
Mariana Mello
1 and
Osvaldo J. M. Nascimento
1,*
1
Department of Neurology, UFF, Antônio Pedro University Hospital (HUAP), Brazil
2
Grande Rio University, UNIGRANRIO, Rio de Janeiro, Brazil
*
Author to whom correspondence should be addressed.
Neurol. Int. 2009, 1(1), e15; https://doi.org/10.4081/ni.2009.e15
Submission received: 25 September 2009 / Revised: 19 October 2009 / Accepted: 26 October 2009 / Published: 3 November 2009

Abstract

The syndrome of progressive, ascending or descending hemiplegia, with no significant sensory impairment was first describes by Mills in 1900, which several cases were reported later. However after diagnostic tests and image improvements, the number of reports has shortened. A possible explanation for this shortage is the identification of other diseases that could mimic the clinical picture. Currently, the syndrome has an uncertain nosological status, since it was described based on clinical examination only. We can find this clinical presentation (Mills syndrome) in cases of amyotrophic lateral sclerosis (ALS), predominant upper motor neuron amyotrophic lateral sclerosis (UMN-ALS) and primary lateral sclerosis (PLS), besides its symptomatic (secondary) forms. We describe a case (initial presentation and one year follow-up) of progressive ascending hemiplegia with clinical isolated upper neuron signs and normal sensory examination, discussing its nosological status, electromyographic findings, differential diagnosis and prognosis.
Keywords: Mills’ syndrome; hemiplegia Mills’ syndrome; hemiplegia

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MDPI and ACS Style

de Gobbi Porto, F.H.; Orsini, M.; Araújo Leite, M.A.; Moreira dos Santos, J.; Pulier, S.; Mello, M.; Nascimento, O.J.M. Mills’ Syndrome: A Case Report. Neurol. Int. 2009, 1, e15. https://doi.org/10.4081/ni.2009.e15

AMA Style

de Gobbi Porto FH, Orsini M, Araújo Leite MA, Moreira dos Santos J, Pulier S, Mello M, Nascimento OJM. Mills’ Syndrome: A Case Report. Neurology International. 2009; 1(1):e15. https://doi.org/10.4081/ni.2009.e15

Chicago/Turabian Style

de Gobbi Porto, Fábio Henrique, Marco Orsini, Marco Antônio Araújo Leite, José Moreira dos Santos, Soraia Pulier, Mariana Mello, and Osvaldo J. M. Nascimento. 2009. "Mills’ Syndrome: A Case Report" Neurology International 1, no. 1: e15. https://doi.org/10.4081/ni.2009.e15

APA Style

de Gobbi Porto, F. H., Orsini, M., Araújo Leite, M. A., Moreira dos Santos, J., Pulier, S., Mello, M., & Nascimento, O. J. M. (2009). Mills’ Syndrome: A Case Report. Neurology International, 1(1), e15. https://doi.org/10.4081/ni.2009.e15

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