Trends in Prevalence and Incidence of Epilepsy and Drug-Resistant Epilepsy in Children: A Nationwide Population-Based Study in Korea
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Population and Definitions of Epilepsy and DRE
2.2. Definitions and Calculations of Prevalence and Incidence
2.3. Statistical Analysis
3. Results
3.1. Prevalence and Incidence of Epilepsy and DRE
3.2. Age- and Sex-Specific Distribution of Patients with Epilepsy and DRE
3.3. Ratio of Incidence of DRE to Incidence of Epilepsy by Year and Age
3.4. Age-Specific Prevalence and Incidence by DRE Type
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Year | Prevalence | Incidence | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Case | Crude * | Age-Standardized | Case | Crude * | Age-Standardized | |||||
A + | AAPC | p | B + | AAPC | p | |||||
2013 | 29,618 | 314.03 | 320.10 | 1.55 | <0.001 | 6294 | 66.73 | 66.89 | 1.53 | <0.01 |
2014 | 28,738 | 312.82 | 320.05 | 5670 | 61.72 | 61.73 | ||||
2015 | 28,285 | 315.62 | 324.30 | 5693 | 63.53 | 63.36 | ||||
2016 | 27,815 | 318.39 | 327.41 | 5540 | 63.42 | 63.19 | ||||
2017 | 27,603 | 325.49 | 334.41 | 5469 | 64.49 | 65.00 | ||||
2018 | 27,210 | 332.79 | 341.37 | 5340 | 65.31 | 66.03 | ||||
2019 | 26,738 | 337.22 | 344.40 | 5262 | 66.36 | 67.33 | ||||
2020 | 26,436 | 342.84 | 346.53 | 5208 | 67.54 | 68.30 | ||||
2021 | 26,697 | 356.72 | 357.17 | 5290 | 70.68 | 71.32 | ||||
2022 | 26,966 | 370.85 | 368.35 | 5323 | 73.20 | 74.06 |
Year | Prevalence | Incidence | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Case | Crude * | Age-Standardized | Case | Crude * | Age-Standardized | |||||
A + | AAPC | p | B + | AAPC | p | |||||
2013 | 2057 | 21.81 | 21.94 | 4.76 | <0.001 | 640 | 6.79 | 6.73 | −0.96 | 0.37 |
2014 | 1938 | 21.1 | 21.26 | 534 | 5.81 | 5.75 | ||||
2015 | 1995 | 22.15 | 22.32 | 598 | 6.67 | 6.52 | ||||
2016 | 2103 | 24.07 | 24.21 | 619 | 7.09 | 6.91 | ||||
2017 | 2147 | 25.32 | 25.62 | 607 | 7.16 | 7.18 | ||||
2018 | 2145 | 26.23 | 26.49 | 501 | 6.13 | 6.12 | ||||
2019 | 2260 | 28.5 | 28.79 | 527 | 6.65 | 6.74 | ||||
2020 | 2201 | 28.54 | 28.67 | 402 | 5.21 | 5.33 | ||||
2021 | 2283 | 30.51 | 30.5 | 438 | 5.85 | 6.07 | ||||
2022 | 2323 | 31.95 | 31.81 | 437 | 6.01 | 6.21 |
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Lee, J.; Choi, A.; Kim, S.; Yoo, I.H. Trends in Prevalence and Incidence of Epilepsy and Drug-Resistant Epilepsy in Children: A Nationwide Population-Based Study in Korea. Neurol. Int. 2024, 16, 880-890. https://doi.org/10.3390/neurolint16040066
Lee J, Choi A, Kim S, Yoo IH. Trends in Prevalence and Incidence of Epilepsy and Drug-Resistant Epilepsy in Children: A Nationwide Population-Based Study in Korea. Neurology International. 2024; 16(4):880-890. https://doi.org/10.3390/neurolint16040066
Chicago/Turabian StyleLee, Jooyoung, Arum Choi, Sukil Kim, and Il Han Yoo. 2024. "Trends in Prevalence and Incidence of Epilepsy and Drug-Resistant Epilepsy in Children: A Nationwide Population-Based Study in Korea" Neurology International 16, no. 4: 880-890. https://doi.org/10.3390/neurolint16040066