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Neurology International
Volume 5
Issue 2
10.4081/ni.2013.e8
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Neurology International is published by MDPI from Volume 12 Issue 3 (2020). Previous articles were published by another publisher in Open Access under a CC-BY licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Case Report

A Discrepancy between Clinical Course and Magnetic Resonance Imaging in a Case of Non-Herpetic Acute Limbic Encephalitis

by
Naoto Kohno
1,*,
Yuko Kawakami
2,
Chizuko Hamada
2,
Genya Toyoda
2,
Hirokazu Bokura
2,
Shuhei Yamaguchi
3 and
Yukitoshi Takahashi
4
1
Department of Neurology, Ohda Municipal Hospital, Ohda
2
Department of Neurology, Shimane Prefectural Central Hospital, Izumo
3
Department of Neurology, Faculty of Medicine, Shimane University, Shimane
4
Department of Research Shizuoka, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan
*
Author to whom correspondence should be addressed.
Neurol. Int. 2013, 5(2), e8; https://doi.org/10.4081/ni.2013.e8
Submission received: 17 April 2012 / Revised: 19 February 2013 / Accepted: 20 March 2013 / Published: 25 June 2013

Abstract

We report the case of a 64-year old man who presented memory disturbance, low-grade fever, weight loss, and bilateral hand tremors for three months. He was diagnosed with non-herpetic acute limbic encephalitis (NHALE). Follow-up magnetic resonance imaging (MRI) revealed new lesions after symptomatic improvement following steroid pulse therapy. This may indicate that there is a time lag between the disturbance or recovery of neurons and astrocytes. Thus, other lesions might occasionally appear during convalescence in patients with NHALE, even if only minimal lesions were found on the initial MRI.
Keywords: non-herpetic acute limbic encephalitis; steroid pulse therapy; magnetic resonance imaging; autoantibodies against glutamate receptors epsilon 2 and delta 2 non-herpetic acute limbic encephalitis; steroid pulse therapy; magnetic resonance imaging; autoantibodies against glutamate receptors epsilon 2 and delta 2

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MDPI and ACS Style

Kohno, N.; Kawakami, Y.; Hamada, C.; Toyoda, G.; Bokura, H.; Yamaguchi, S.; Takahashi, Y. A Discrepancy between Clinical Course and Magnetic Resonance Imaging in a Case of Non-Herpetic Acute Limbic Encephalitis. Neurol. Int. 2013, 5, e8. https://doi.org/10.4081/ni.2013.e8

AMA Style

Kohno N, Kawakami Y, Hamada C, Toyoda G, Bokura H, Yamaguchi S, Takahashi Y. A Discrepancy between Clinical Course and Magnetic Resonance Imaging in a Case of Non-Herpetic Acute Limbic Encephalitis. Neurology International. 2013; 5(2):e8. https://doi.org/10.4081/ni.2013.e8

Chicago/Turabian Style

Kohno, Naoto, Yuko Kawakami, Chizuko Hamada, Genya Toyoda, Hirokazu Bokura, Shuhei Yamaguchi, and Yukitoshi Takahashi. 2013. "A Discrepancy between Clinical Course and Magnetic Resonance Imaging in a Case of Non-Herpetic Acute Limbic Encephalitis" Neurology International 5, no. 2: e8. https://doi.org/10.4081/ni.2013.e8

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