Next Article in Journal
An Acute, Placebo-Controlled, Single-Blind, Crossover, Dose-Response, Exploratory Study to Assess the Effects of New Zealand Pine Bark Extract (Enzogenol®) on Glycaemic Responses in Healthy Participants
Next Article in Special Issue
The Link between Hypermetabolism and Hypernatremia in Severely Burned Patients
Previous Article in Journal
Effects of Coffee Intake on Dyslipidemia Risk According to Genetic Variants in the ADORA Gene Family among Korean Adults
Previous Article in Special Issue
Impending Low Intake Dehydration at Admission to A Geriatric Ward- Prevalence and Correlates in a Cross-Sectional Study
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Nutrients
Volume 12
Issue 2
10.3390/nu12020496
Review Report
nutrients-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
Article
Peer-Review Record

What Serum Sodium Concentration Is Suggestive for Underhydration in Geriatric Patients?

Nutrients 2020, 12(2), 496; https://doi.org/10.3390/nu12020496
by Zyta Beata Wojszel 1,2
Reviewer 1: Anonymous
Nutrients 2020, 12(2), 496; https://doi.org/10.3390/nu12020496
Submission received: 1 January 2020 / Revised: 11 February 2020 / Accepted: 13 February 2020 / Published: 15 February 2020
(This article belongs to the Special Issue Body Water Regulation and Nutrient Intake)

Round 1

Reviewer 1 Report

The goals of this study was to evaluate whether specific blood markers were useful in detecting dehydration in a cohort of geriatric patients and establish cutoff values for such markers. A secondary analysis of data collected from a previous study was used to achieve these goals. 

Based upon lines 125-126, the major finding from this work is that sodium was the better predictor for dehydration compared to urea, glucose and potassium. Based upon this finding, the major issue with this manuscript is that there isn't an explanation is the discussion as to why this finding is important or its relevance to human health. The title has sodium in it, but there isn't anything about sodium in the introduction or why sodium concentrations (or the other markers) are important to the detection of dehydration in geriatric patients. There is a lot of text about the diagnostic process and the Khajuria and Krahdan equation, but nothing regarding the public health relevance of this work. Why is this important?

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Reviewer 2 Report

This is a generally well-written manuscript on a topic of interest to a wide variety of healthcare providers.  Analysis of the findings considering statistically significant differences the hydrated and dehydrated samples is required.  In addition, both introduction revisions and discussion of the results in light of the apparent purpose, recommendation of a lower threshold for serum sodium, are necessary.

Comments for author File: Comments.pdf

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Round 2

Reviewer 2 Report

Thank you for the detailed response to comments.  The manuscript is greatly improved.  Some minor grammar/punctuation needs to be corrected during proofing.  The only correction required at this time is line 254 - fail should be 'frail'.  

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Back to TopTop