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Review

Role of Vitamin K in Selected Malignant Neoplasms in Women

1
Department of Perinatology and Women’s Health, Poznań University of Medical Sciences, 60-535 Poznań, Poland
2
Department of Medical Chemistry, Faculty of Chemistry, Adam Mickiewicz University, 61-614 Poznań, Poland
3
Department of Oncology, Gynecological Oncology, Poznań University of Medical Sciences, 60-569 Poznań, Poland
*
Author to whom correspondence should be addressed.
Nutrients 2022, 14(16), 3401; https://doi.org/10.3390/nu14163401
Submission received: 31 July 2022 / Revised: 11 August 2022 / Accepted: 17 August 2022 / Published: 18 August 2022
(This article belongs to the Special Issue Vitamin, Mineral, and Diet Supplementation for Women Health)

Abstract

The main function of vitamin K in the human organism is its activity in the blood clotting cascade. Epidemiological studies suggest that reduced intake of vitamin K may contribute to an increased risk of geriatric diseases such as atherosclerosis, dementia, osteoporosis, and osteoarthritis. A growing number of studies also indicate that vitamin K may be involved not only in preventing the development of certain cancers but it may also support classical cancer chemotherapy. This review article summarizes the results of studies on the anticancer effects of vitamin K on selected female malignancies, i.e., breast, cervical, and ovarian cancer, published over the past 20 years. The promising effects of vitamin K on cancer cells observed so far indicate its great potential, but also the need for expansion of our knowledge in this area by conducting extensive research, including clinical trials.
Keywords: vitamin K; breast cancer; cervical cancer; ovarian cancer vitamin K; breast cancer; cervical cancer; ovarian cancer

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MDPI and ACS Style

Markowska, A.; Antoszczak, M.; Markowska, J.; Huczyński, A. Role of Vitamin K in Selected Malignant Neoplasms in Women. Nutrients 2022, 14, 3401. https://doi.org/10.3390/nu14163401

AMA Style

Markowska A, Antoszczak M, Markowska J, Huczyński A. Role of Vitamin K in Selected Malignant Neoplasms in Women. Nutrients. 2022; 14(16):3401. https://doi.org/10.3390/nu14163401

Chicago/Turabian Style

Markowska, Anna, Michał Antoszczak, Janina Markowska, and Adam Huczyński. 2022. "Role of Vitamin K in Selected Malignant Neoplasms in Women" Nutrients 14, no. 16: 3401. https://doi.org/10.3390/nu14163401

APA Style

Markowska, A., Antoszczak, M., Markowska, J., & Huczyński, A. (2022). Role of Vitamin K in Selected Malignant Neoplasms in Women. Nutrients, 14(16), 3401. https://doi.org/10.3390/nu14163401

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