Maternal Consumption of a Cafeteria Diet during Lactation Leads to Altered Diet-Induced Thermogenesis in Descendants after Exposure to a Western Diet in Adulthood
Abstract
:1. Introduction
2. Materials and Methods
2.1. Ethics Statement
2.2. Experimental Design
2.3. Analysis of Blood Parameters
2.4. RNA Extraction and Gene Expression Analysis
2.5. UCP1 Protein Levels
2.6. Statistical Analysis
3. Results
3.1. Effects of Maternal Cafeteria Diet Intake during Lactation on Phenotypic Parameters and Food Intake in the Offspring
3.2. Effects of Maternal Exposure to a Cafeteria Diet during Lactation on the Expression of Selected Genes in BAT of the Offspring
3.2.1. Results in Young Animals (PN22)
3.2.2. Results in Adult Animals (24 Weeks) after Exposure to Western Diet
3.2.3. Results in Adult Animals (24 Weeks) That Were Maintained under Standard Diet
3.3. Western Blot Analysis of UCP1 in BAT in Young Animals (PN22) and in Adult Animals (24 Weeks) after Exposure to Western Diet
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Conflicts of Interest
References
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Pomar, C.A.; Picó, C.; Palou, A.; Sánchez, J. Maternal Consumption of a Cafeteria Diet during Lactation Leads to Altered Diet-Induced Thermogenesis in Descendants after Exposure to a Western Diet in Adulthood. Nutrients 2022, 14, 1958. https://doi.org/10.3390/nu14091958
Pomar CA, Picó C, Palou A, Sánchez J. Maternal Consumption of a Cafeteria Diet during Lactation Leads to Altered Diet-Induced Thermogenesis in Descendants after Exposure to a Western Diet in Adulthood. Nutrients. 2022; 14(9):1958. https://doi.org/10.3390/nu14091958
Chicago/Turabian StylePomar, Catalina Amadora, Catalina Picó, Andreu Palou, and Juana Sánchez. 2022. "Maternal Consumption of a Cafeteria Diet during Lactation Leads to Altered Diet-Induced Thermogenesis in Descendants after Exposure to a Western Diet in Adulthood" Nutrients 14, no. 9: 1958. https://doi.org/10.3390/nu14091958