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Nutrients
Volume 16
Issue 12
10.3390/nu16121878
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Review

The Role of Vitamin D3 in Ocular Diseases

by
Małgorzata Mrugacz
1,*,
Kamila Pieńczykowska
2 and
Anna Bryl
1
1
Department of Ophthalmology and Eye Rehabilitation, Medical University of Bialystok, 15-089 Białystok, Poland
2
The Medical University of Bialystok Clinical Hospital, 15-089 Białystok, Poland
*
Author to whom correspondence should be addressed.
Nutrients 2024, 16(12), 1878; https://doi.org/10.3390/nu16121878
Submission received: 6 May 2024 / Revised: 29 May 2024 / Accepted: 3 June 2024 / Published: 14 June 2024
(This article belongs to the Section Nutrition and Public Health)
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Abstract

Vitamin D3 plays a vital role in numerous physiological processes within the human body, including having a positive effect on eye health. It is renowned for its immunomodulatory, anti-inflammatory, antioxidant, and angiogenic properties. Its deficiency is evolving into a significant global challenge. In order to explain the connection between vitamin D3 and various ocular diseases, 84 relevant studies, mainly from the PubMed database, published in English between 1999 and 2024 were analyzed. Ocular tissues can activate and regulate vitamin D levels, which emphasizes the significance of this nutrient in maintaining eye homeostasis. While there is suggestive evidence for a probable association between vitamin D3 and ocular health, more robust research is needed to establish causation and inform clinical guidelines.
Keywords: vitamin D; eye disease; cholecalciferol; glaucoma; keratoconus vitamin D; eye disease; cholecalciferol; glaucoma; keratoconus

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MDPI and ACS Style

Mrugacz, M.; Pieńczykowska, K.; Bryl, A. The Role of Vitamin D3 in Ocular Diseases. Nutrients 2024, 16, 1878. https://doi.org/10.3390/nu16121878

AMA Style

Mrugacz M, Pieńczykowska K, Bryl A. The Role of Vitamin D3 in Ocular Diseases. Nutrients. 2024; 16(12):1878. https://doi.org/10.3390/nu16121878

Chicago/Turabian Style

Mrugacz, Małgorzata, Kamila Pieńczykowska, and Anna Bryl. 2024. "The Role of Vitamin D3 in Ocular Diseases" Nutrients 16, no. 12: 1878. https://doi.org/10.3390/nu16121878

APA Style

Mrugacz, M., Pieńczykowska, K., & Bryl, A. (2024). The Role of Vitamin D3 in Ocular Diseases. Nutrients, 16(12), 1878. https://doi.org/10.3390/nu16121878

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