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Micromachines, Volume 9, Issue 1

2018 January - 40 articles

Cover Story: Bioelectronic medicine has been hailed as a new type of medicine to treat/manage chronic diseases. Unlike pharmaceutical products in which pharmacological agents target the molecular/cell mechanism related to the targeted tissues/organs via systemic blood circulation, bioelectronic medicine aims to modulate the mechanism through electrical neuromodulation, using miniaturized implantable devices. This paper presents a miniaturized wireless implant that is applicable not only for GI dysmotility, but can also be used for diseases/injuries associated with the central/peripheral/autonomic nervous systems. View this paper
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Articles (40)

  • Article
  • Open Access
17 Citations
5,480 Views
9 Pages

Investigation on the Quality Factor Limit of the (111) Silicon Based Disk Resonator

  • Xin Zhou,
  • Dingbang Xiao,
  • Qingsong Li,
  • Qian Hu,
  • Zhanqiang Hou,
  • Kaixuan He,
  • Zhihua Chen,
  • Chun Zhao,
  • Yulie Wu and
  • Ashwin Seshia
  • + 1 author

22 January 2018

Quality factor is one of the most important parameters for a MEMS resonator. Most MEMS resonators are dominated by thermoelastic dissipation (TED). This paper demonstrates that the TED in a disk resonator that is made of (111) single-crystal silicon...

  • Article
  • Open Access
54 Citations
7,644 Views
17 Pages

In Vivo Experimental Study of Noninvasive Insulin Microinjection through Hollow Si Microneedle Array

  • Drago Resnik,
  • Matej Možek,
  • Borut Pečar,
  • Andrej Janež,
  • Vilma Urbančič,
  • Ciprian Iliescu and
  • Danilo Vrtačnik

20 January 2018

An experimental study of in vivo insulin delivery through microinjection by using hollow silicon microneedle array is presented. A case study was carried out on a healthy human subject in vivo to determine the influence of delivery parameters on drug...

  • Article
  • Open Access
7 Citations
4,665 Views
12 Pages

Chemical Mechanical Planarization and Old Italian Violins

  • Ara Philipossian,
  • Yasa Sampurno and
  • Lauren Peckler

18 January 2018

Previous studies have shown that spectral analysis based on force data can elucidate fundamental physical phenomena during chemical mechanical planarization (CMP). While it has not been literally described elsewhere, such analysis was partly motivate...

  • Feature Paper
  • Article
  • Open Access
2 Citations
5,327 Views
13 Pages

A Platform for Mechano(-Electrical) Characterization of Free-Standing Micron-Sized Structures and Interconnects

  • Angel Savov,
  • Shivani Joshi,
  • Salman Shafqat,
  • Johan Hoefnagels,
  • Marcus Louwerse,
  • Ronald Stoute and
  • Ronald Dekker

18 January 2018

A device for studying the mechanical and electrical behavior of free-standing micro-fabricated metal structures, subjected to a very large deformation, is presented in this paper. The free-standing structures are intended to serve as interconnects in...

  • Article
  • Open Access
3 Citations
4,708 Views
11 Pages

17 January 2018

Wireless medical body-area networks are used to connect sensor nodes that monitor vital parameters. The radio consumes a large portion of the sensor energy budget, and hence its power dissipation should be minimized. The low-noise amplifier (LNA) is...

  • Article
  • Open Access
11 Citations
4,447 Views
8 Pages

Pair Interaction of Catalytical Sphere Dimers in Chemically Active Media

  • Jing-Min Shi,
  • Ru-Fei Cui,
  • Jie Xiao,
  • Li-Yan Qiao,
  • Jun-Wen Mao and
  • Jiang-Xing Chen

17 January 2018

We study the pair dynamics of two self-propelled sphere dimers in the chemically active medium in which a cubic autocatalytic chemical reaction takes place. Concentration gradient around the dimer, created by reactions occurring on the catalytic sphe...

  • Review
  • Open Access
67 Citations
8,951 Views
14 Pages

17 January 2018

Food safety remains one of the most important issues in most countries and the detection of food hazards plays a key role in the systematic approach to ensuring food safety. Rapid, easy-to-use and low-cost analytical tools are required to detect chem...

  • Feature Paper
  • Article
  • Open Access
13 Citations
7,344 Views
10 Pages

17 January 2018

Forming microspheres or microbeads from nanofibrous materials has recently attracted research interest for their applications in various fields, because these structures greatly impact cellular behaviors and functions. However, conventional methods o...

  • Article
  • Open Access
17 Citations
5,757 Views
19 Pages

17 January 2018

The micro-electro-mechanical system (MEMS) resonator developed based on surface processing technology usually changes the section shape either due to excessive etching or insufficient etching. In this paper, a section parameter is proposed to describ...

  • Article
  • Open Access
39 Citations
5,617 Views
7 Pages

3D Multi-Microchannel Helical Mixer Fabricated by Femtosecond Laser inside Fused Silica

  • Chao Shan,
  • Feng Chen,
  • Qing Yang,
  • Zhuangde Jiang and
  • Xun Hou

16 January 2018

Three-dimensional (3D) multi-microchannel mixers can meet the requirements of different combinations according to actual needs. Rapid and simple creation of 3D multi-microchannel mixers in a “lab-on-a-chip” platform is a significant challenge in micr...

  • Article
  • Open Access
28 Citations
8,346 Views
11 Pages

15 January 2018

Cutting force measurement is a quintessential task for status monitoring during machining. In the past, a number of cutting force sensors have been developed, each featuring a different set of performance advantages. In a pursuit to improve the measu...

  • Article
  • Open Access
21 Citations
9,329 Views
20 Pages

14 January 2018

Additive manufacturing, such as fused deposition modeling (FDM), has been increasingly employed to produce microfluidic platforms due to ease of use, wide distribution of affordable 3D printers and relatively inexpensive materials for printing. In th...

  • Article
  • Open Access
16 Citations
4,692 Views
12 Pages

Atomistic and Experimental Investigation of the Effect of Depth of Cut on Diamond Cutting of Cerium

  • Junjie Zhang,
  • Maobing Shuai,
  • Haibing Zheng,
  • Yao Li,
  • Ming Jin and
  • Tao Sun

13 January 2018

The ultra-precision diamond cutting process exhibits strong size effects due to the ultra-small depth of cut that is comparable with the cutting edge radius. In the present work, we elucidate the underlying machining mechanisms of single crystal ceri...

  • Article
  • Open Access
11 Citations
6,440 Views
15 Pages

13 January 2018

Polymeric drug delivery systems usually deliver drugs by diffusion with an initial burst of release followed by a slower prolonged release phase. An optimal system would release exact doses of drugs using an on-demand external actuation system. The p...

  • Article
  • Open Access
3 Citations
6,539 Views
9 Pages

On-Chip Facile Preparation of Monodisperse Resorcinol Formaldehyde (RF) Resin Microspheres

  • Jianmei Wang,
  • Xiaowen Huang,
  • Pei Zhao,
  • Xueying Wang,
  • Ye Tian,
  • Chengmin Chen,
  • Jianchun Wang,
  • Yan Li,
  • Wei Wan and
  • Liqiu Wang
  • + 3 authors

12 January 2018

Monodisperse resorcinol formaldehyde resin (RF) microspheres are an important polymeric material because of their rich surface functional group and uniform structural characteristics and have been increasingly applied as an electrode material, cataly...

  • Feature Paper
  • Article
  • Open Access
24 Citations
8,545 Views
11 Pages

Hydrophobic Janus Foam Motors: Self-Propulsion and On-The-Fly Oil Absorption

  • Xiaofeng Li,
  • Fangzhi Mou,
  • Jingjing Guo,
  • Zhuoyi Deng,
  • Chuanrui Chen,
  • Leilei Xu,
  • Ming Luo and
  • Jianguo Guan

11 January 2018

In this work, we for the first time have proposed and fabricated a self-propelled Janus foam motor for on-the-fly oil absorption on water by simply loading camphor/stearic acid (SA) mixture as fuels into one end of the SA-modified polyvinyl alcohol (...

  • Article
  • Open Access
22 Citations
8,335 Views
8 Pages

9 January 2018

Dielectrophoresis in microfluidics provides a useful tool to test biomechanics of living cells, regardless of surface charges on cell membranes. We have designed an experimental method to characterize the nonlinear viscoelastic behaviors of single ce...

  • Article
  • Open Access
20 Citations
5,477 Views
17 Pages

9 January 2018

Obtaining a correlation factor is a prerequisite for fusing multiple outputs of a mircoelectromechanical system (MEMS) gyroscope array and evaluating accuracy improvement. In this paper, a mathematical statistics method is established to analyze and...

  • Article
  • Open Access
12 Citations
6,057 Views
18 Pages

A Changeable Lab-on-a-Chip Detector for Marine Nonindigenous Microorganisms in Ship’s Ballast Water

  • Myint Myint Maw,
  • Xinxiang Pan,
  • Zhen Peng,
  • Yanjuan Wang,
  • Long Zhao,
  • Bowen Dai and
  • Junsheng Wang

5 January 2018

The spread and invasion of many nonindigenous species in the ship’s ballast water around the world has been a hazard and threat to ecology, economy, and human health. The rapid and accurate detection of marine invasive species in ship’s ballast water...

  • Feature Paper
  • Article
  • Open Access
30 Citations
10,820 Views
13 Pages

A Wireless Implant for Gastrointestinal Motility Disorders

  • Yi-Kai Lo,
  • Po-Min Wang,
  • Genia Dubrovsky,
  • Ming-Dao Wu,
  • Michael Chan,
  • James C. Y. Dunn and
  • Wentai Liu

2 January 2018

Implantable functional electrical stimulation (IFES) has demonstrated its effectiveness as an alternative treatment option for diseases incurable pharmaceutically (e.g., retinal prosthesis, cochlear implant, spinal cord implant for pain relief). Howe...

  • Article
  • Open Access
106 Citations
12,277 Views
12 Pages

A Paper-Based Piezoelectric Accelerometer

  • Yu-Hsuan Wang,
  • Pengfei Song,
  • Xiao Li,
  • Changhai Ru,
  • Giovanni Ferrari,
  • Prabakaran Balasubramanian,
  • Marco Amabili,
  • Yu Sun and
  • Xinyu Liu

2 January 2018

This paper presents the design and testing of a one-axis piezoelectric accelerometer made from cellulose paper and piezoelectric zinc oxide nanowires (ZnO NWs) hydrothermally grown on paper. The accelerometer adopts a cantilever-based configuration w...

  • Article
  • Open Access
19 Citations
7,616 Views
18 Pages

1 January 2018

Magnetic drug targeting is a promising technique that can deliver drugs to the diseased region, while keeping the drug away from healthy parts of body. Introducing a human in the control loop of a targeted drug delivery system and using inherent bila...

  • Communication
  • Open Access
16 Citations
6,730 Views
7 Pages

Towards Miniaturization of Magnetic Gears: Torque Performance Assessment

  • Efren Diez-Jimenez,
  • Rocio Sanchez-Montero and
  • Miriam Martinez-Muñoz

31 December 2017

Magnetomechanical components can be a good solution in order to reduce, or even completely avoid, friction phenomena in micro-electro-mechanical systems (MEMS) since they can transmit forces through magnetic fields without contacts. In this communica...

  • Article
  • Open Access
39 Citations
8,413 Views
10 Pages

The Design, Fabrication, and Testing of an Electromagnetic Micropump with a Matrix-Patterned Magnetic Polymer Composite Actuator Membrane

  • Muzalifah Mohd Said,
  • Jumril Yunas,
  • Badariah Bais,
  • Azrul Azlan Hamzah and
  • Burhanuddin Yeop Majlis

31 December 2017

A valveless electromagnetic (EM) micropump with a matrix-patterned magnetic polymer composite actuator membrane structure was successfully designed and fabricated. The composite membrane structure is made of polydemethylsiloxane (PDMS) that is mixed...

  • Article
  • Open Access
41 Citations
6,652 Views
22 Pages

New MEMS Tweezers for the Viscoelastic Characterization of Soft Materials at the Microscale

  • Paolo Di Giamberardino,
  • Alvise Bagolini,
  • Pierluigi Bellutti,
  • Imre J. Rudas,
  • Matteo Verotti,
  • Fabio Botta and
  • Nicola P. Belfiore

30 December 2017

As many studies show, there is a relation between the tissue’s mechanical characteristics and some specific diseases. Knowing this relationship would help early diagnosis or microsurgery. In this paper, a new method for measuring the viscoelastic pro...

  • Review
  • Open Access
43 Citations
10,355 Views
15 Pages

Controllable Swarming and Assembly of Micro/Nanomachines

  • Conghui Liu,
  • Tailin Xu,
  • Li-Ping Xu and
  • Xueji Zhang

29 December 2017

Motion is a common phenomenon in biological processes. Major advances have been made in designing various self-propelled micromachines that harvest different types of energies into mechanical movement to achieve biomedicine and biological application...

  • Letter
  • Open Access
5 Citations
4,861 Views
9 Pages

Microwave Wire Interrogation Method Mapping Pressure under High Temperatures

  • Xiaoyong Chen,
  • Dan Yan,
  • Yingping Hong,
  • Ting Liang and
  • Jijun Xiong

29 December 2017

It is widely accepted that wireless reading for in-situ mapping of pressure under high-temperature environments is the most feasible method, because it is not subject to frequent heterogeneous jointing failures and electrical conduction deteriorating...

  • Article
  • Open Access
2 Citations
4,873 Views
11 Pages

29 December 2017

An efficient electron field emitter based on a monolayer graphene coated well aligned Mo tip array has been designed, fabricated, and evaluated. The advantages of this hybrid nanostructure film morphology are explored and discussed. Efficient and sta...

  • Article
  • Open Access
1 Citations
4,919 Views
8 Pages

28 December 2017

It is technically difficult to acquire large-field images under the complexity and cost restrictions of a diagnostic and instant field research purpose. The goal of the introduced large-field imaging system is to achieve a tolerable resolution for de...

  • Article
  • Open Access
56 Citations
9,215 Views
15 Pages

Analysis of Passive Mixing in a Serpentine Microchannel with Sinusoidal Side Walls

  • Muhammad Usman Javaid,
  • Taqi Ahmad Cheema and
  • Cheol Woo Park

28 December 2017

Sample mixing is difficult in microfluidic devices because of laminar flow. Micromixers are designed to ensure the optimal use of miniaturized devices. The present study aims to design a chaotic-advection-based passive micromixer with enhanced mixing...

  • Article
  • Open Access
11 Citations
6,125 Views
19 Pages

The Viability of Single Cancer Cells after Exposure to Hydrodynamic Shear Stresses in a Spiral Microchannel: A Canine Cutaneous Mast Cell Tumor Model

  • Dettachai Ketpun,
  • Achariya Sailasuta,
  • Thammawit Suwannaphan,
  • Sudchaya Bhanpattanakul,
  • Alongkorn Pimpin,
  • Werayut Srituravanich,
  • Witsaroot Sripumkhai,
  • Wutthinan Jeamsaksiri and
  • Prapruddee Piyaviriyakul

28 December 2017

Our laboratory has the fundamental responsibility to study cancer stem cells (CSC) in various models of human and animal neoplasms. However, the major impediments that spike our accomplishment are the lack of universal biomarkers and cellular heterog...

  • Article
  • Open Access
44 Citations
6,800 Views
14 Pages

Design of a Compact Wireless Multi-Channel High Area-Efficient Stimulator with Arbitrary Channel Configuration

  • Yuwei Zhang,
  • Deng Luo,
  • Ting Ou,
  • Zhangyi Yuan,
  • Heng Huang,
  • Ling You,
  • Yin Yue,
  • Milin Zhang,
  • Dongmei Li and
  • Zhihua Wang
  • + 2 authors

27 December 2017

This paper presents the design of a wireless, implantable, multi-channel, programmable stimulator with arbitrary channel combination. A novel channel management module using a switch array is presented, enabling arbitrary channel configuration with a...

  • Article
  • Open Access
14 Citations
5,790 Views
15 Pages

Experimental Study of Back Wall Dross and Surface Roughness in Fiber Laser Microcutting of 316L Miniature Tubes

  • Erika García-López,
  • Alexis G. Medrano-Tellez,
  • Juansethi R. Ibarra-Medina,
  • Hector R. Siller and
  • Ciro A. Rodriguez

26 December 2017

Laser cutting is a key technology for the medical devices industry, providing the flexibility, and precision for the processing of sheets, and tubes with high quality features. In this study, extensive experimentation was used to evaluate the effect...

  • Article
  • Open Access
12 Citations
6,681 Views
13 Pages

Research of a Novel Ultra-High Pressure Sensor with High-Temperature Resistance

  • Guo-Dong Zhang,
  • Yu-Long Zhao,
  • Yun Zhao,
  • Xin-Chen Wang and
  • Xue-Yong Wei

25 December 2017

Ultra-high pressure measurement has significant applications in various fields such as high pressure synthesis of new materials and ultra-high pressure vessel monitoring. This paper proposes a novel ultra-high pressure sensor combining a truncated-co...

  • Article
  • Open Access
7 Citations
7,336 Views
18 Pages

Rhombic-Shaped Channel Stent with Enhanced Drug Capacity and Fatigue Life

  • Hao-Ming Hsiao,
  • Cheng-Han Lin,
  • Yung-Kang Shen,
  • Tzu-Yun Chou and
  • Yen-Yu Hsu

24 December 2017

A drug-eluting stent with rhombic-shaped drug reservoirs is proposed, aimed at providing long-term drug delivery and enhanced fatigue life. Unique rhombic-shaped reservoirs or channels on the stent struts can increase the total drug capacity and impr...

  • Article
  • Open Access
6 Citations
4,396 Views
14 Pages

23 December 2017

Micro-opto-electro-mechanical (MOEMS) micromirrors are an enabling technology for mobile image projectors (pico-projectors). Low size and low power are the crucial pico-projector constraints. In this work, we present a fast method for the optimizatio...

  • Article
  • Open Access
19 Citations
6,326 Views
10 Pages

21 December 2017

In this study, we successfully designed and tested a new micropump that utilizes an active check valve and bottom-protruding structure to achieve sample transportation. We performed theoretical analyses and numerical simulations to determine the opti...

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Micromachines - ISSN 2072-666X