Modern Radiotherapy for Pediatric Brain Tumors
Abstract
:1. Introduction
2. Physical and Dosimetric Principles
2.1. Depth-Dose Properties: Photons
2.2. Depth-Dose Properties: Protons
2.3. Treatment Delivery: Photons
2.4. Treatment Delivery: Protons
3. Treatment Planning
4. Treatment Outcomes for Select Histologies
4.1. Medulloblastoma
4.2. Ependymoma
4.3. Glioma
5. Late Effects
5.1. Neurocognition
5.2. Neuroendocrine Function
5.3. Hearing
5.4. Cerebrovascular Effects
5.4.1. Moyamoya
5.4.2. Cavernomas and Cerebrovascular Bleeds
5.4.3. Stroke
5.4.4. Post-Treatment Surveillance
5.5. Relative Biologic Effectiveness and Brainstem Toxicity
5.6. Alopecia
5.7. Second Neoplasms
6. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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DeNunzio, N.J.; Yock, T.I. Modern Radiotherapy for Pediatric Brain Tumors. Cancers 2020, 12, 1533. https://doi.org/10.3390/cancers12061533
DeNunzio NJ, Yock TI. Modern Radiotherapy for Pediatric Brain Tumors. Cancers. 2020; 12(6):1533. https://doi.org/10.3390/cancers12061533
Chicago/Turabian StyleDeNunzio, Nicholas J., and Torunn I. Yock. 2020. "Modern Radiotherapy for Pediatric Brain Tumors" Cancers 12, no. 6: 1533. https://doi.org/10.3390/cancers12061533