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Systematic Review
Peer-Review Record

Additional Value of PET Radiomic Features for the Initial Staging of Prostate Cancer: A Systematic Review from the Literature

Cancers 2021, 13(23), 6026; https://doi.org/10.3390/cancers13236026
by Priscilla Guglielmo 1,†, Francesca Marturano 2,†, Andrea Bettinelli 2, Michele Gregianin 1, Marta Paiusco 2 and Laura Evangelista 3,*
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Reviewer 3:
Cancers 2021, 13(23), 6026; https://doi.org/10.3390/cancers13236026
Submission received: 2 November 2021 / Revised: 23 November 2021 / Accepted: 26 November 2021 / Published: 30 November 2021
(This article belongs to the Special Issue PET/CT in Prostate Cancer)

Round 1

Reviewer 1 Report

The authors describe a systematic review from the literature on the additional value of PET radiomic features for the initial staging of prostate cancer 

The paper is interesting and well written. Comments and limitations are clearly reported. Discussion and conclusions are appropriate.

Author Response

We are really thankful to the reviewers for their kind comments.

Reviewer 2 Report

This is a well conducted systematic review of the current literature examining the role of radiomics applied to early stage prostate cancer imaged with PET/CT and PET/MRI. The literature is succinctly and clearly summarized and appropriate conclusions drawn. The ranking of the papers by the RQS standards is a strength of the analysis and identifies areas for investigators to concentrate efforts to improve the quality of research.

Author Response

We are really thankful to the reviewers for their kind comments.

Reviewer 3 Report

This study performed a systematic review of the literature to provide an overview on the potential application, in terms of additional value over clinical data, of PET radiomics in the initial staging of prostate cancer. I think that this article is well written and its contents may be useful for the readers of Cancers and worthy of publication.As an additional comment to improve the article before publication, please unify the reference form (for example, number of reference).

Author Response

We are really thankful to the reviewers for their kind comments.

We have modified the references, as requested.

Moreover, a careful English revision has been made.

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