Next Article in Journal
Advances in Diagnosis and Therapy for Bladder Cancer
Next Article in Special Issue
The Diagnostic Value of the Added MR Imaging of the Scrotum in the Preoperative Workup of Sonographically Indeterminate Testicular Lesions—A Retrospective Multicenter Analysis
Previous Article in Journal
Prospective Comparison of the Performance of MRI Versus CT in the Detection and Evaluation of Peritoneal Surface Malignancies
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Cancers
Volume 14
Issue 13
10.3390/cancers14133180
Review Report
cancers-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
Review
Peer-Review Record

Imaging of Pediatric Testicular and Para-Testicular Tumors: A Pictural Review

Cancers 2022, 14(13), 3180; https://doi.org/10.3390/cancers14133180
by Anne-Laure Hermann 1,*, Aurore L’Herminé-Coulomb 2, Sabine Irtan 3, Georges Audry 4, Liesbeth Cardoen 4, Hervé J. Brisse 4, Saskia Vande Perre 1 and Hubert Ducou Le Pointe 1
Reviewer 1:
Malene Pedersen
Reviewer 2:
André Vis
Cancers 2022, 14(13), 3180; https://doi.org/10.3390/cancers14133180
Submission received: 12 June 2022 / Revised: 24 June 2022 / Accepted: 27 June 2022 / Published: 29 June 2022
(This article belongs to the Special Issue Testicular Tumor Imaging)

Round 1

Reviewer 1 Report

Well written manuscript.

Informing images and an interesting focus of this paper.

Well done.

 

I have only very few comments

 

Consider including a “pictural review” or review in the title.

 

Consider including a few comments on your method. How did you select the papers? Maybe a figure/table including all the tumors and % prevalence?

 

There seems to be a couple of errors in the list of references e.g., Ref 43 and 53.

 

Consider elaborating on the use of SWE elastography. There are many interesting papers on this subject, and it is important as this clinical tool can help assess testicular tumors.

 

What about the combination of US elastography and MRI in testicular tumors? Here is also a couple of papers on this comparing normal testis tissue with tumors and microlithiasis. 

 

In pediatric patients, testicular microlithiasis has been reported to vanish over time. There are elastography papers on patients with microlithiasis. Consider including this information.

 

any thoughts on limitations?

Author Response

Please see the attachment

Author Response File: Author Response.docx

Reviewer 2 Report

This is a well written paper on the role of different imaging modules in the diagnosis, and follow-up of testicular cancers in childhood. 

The authors give a nice summary on the disease itself, which overall might give some distraction. 

As a reader, and treating testicular cancer (mostly in a more elderly population), I would like to know what are the sensitivity and specificity of the different imaging modules for malignancy when compared to  the final histology. In other words, why do the authors claim that more modern imaging modules are superior to the older ones if no mentioning of accuracy is performed. So, could the authors state the more modern imaging tools are better and are more likely to detect malignancy? 

Could the authors give an estimation in what proportion of patients, organ sparing surgery is performed by using modern imaging techniques in stead of whole organ resecting surgery by classic imaging?    

Author Response

Please see the attachment

Author Response File: Author Response.docx

Back to TopTop