Treatment Outcomes of Computer Tomography-Guided Brachytherapy in Cervical Cancer in Hong Kong: A Retrospective Review
, Matthew Ho-Fai Cheng 2, Jacky Tsun-Kit Wu 2, Cheuk-Wai Choi 3, Rosa Piu-Ying Tse 4, Patty Piu-Ying Ho 4, Emina Edith Cheung 1, Andy Cheung 4, Ka-Yu Test 5, Karen Kar-Loen Chan 5, Hexane Yuen-Sheung Ngan 5, Steven Wai-Kwan Siu 4, Roger Kai-Cheong Ngan 1,6 and Anne Wing-Mui Lee 1,7
Round 1
Reviewer 1 Report
This is the revised version of the article entitled “Treatment Outcomes of Computer Tomography-Guided Brachytherapy in Cervical Cancer in Hong Kong: A retro-spective review”. This is interesting topic in this field. Revision procedure performed well written according to the issues that had been pointed out. However, there are minor point of issues.
I believe that the manuscript would be more clinically meaningful if this point were added.
1. It is staged at FIGO 2009 but should be re-staged at FIGO 2018 as it is not difficult to re-stage at FIGO 2018.
Reviewer 2 Report
The authors have adequately addressed my concerns about this manuscript. If I may add and comment on references 45–46 and the associated discussion, the following additional papers have been published on carbon-ion RT for adenocarcinoma of the uterus cervix.
# A phase 1/2 study of C-ion RT with concurrent chemotherapy: PMID: 30825494
# A propensity score-matched analysis for concurrent use of chemotherapy for C-ion RT: PMID: 31891228
# A multi-institutional retrospective analysis of C-ion RT: PMID: 34072676
These references may enhance the discussion in this manuscript. However, this manuscript is a report on 3D-IGBT, and it would be up to the author's preference as to how far to include the above papers. I would like to make an additional comment for the authors, but I think it deserves to be accepted in its current state.
Thanks.
