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Tat-hspb1 Suppresses Clear Cell Renal Cell Carcinoma (ccRCC) Growth via Lysosomal Membrane Permeabilization
 
 
Review
Peer-Review Record

The Continuing Question of Adjuvant Therapy in Clear Cell Renal Cell Carcinoma

Cancers 2022, 14(24), 6018; https://doi.org/10.3390/cancers14246018
by Stephanie A. Berg * and Bradley A. McGregor *
Reviewer 1: Anonymous
Reviewer 2:
Cancers 2022, 14(24), 6018; https://doi.org/10.3390/cancers14246018
Submission received: 17 October 2022 / Revised: 29 November 2022 / Accepted: 2 December 2022 / Published: 7 December 2022
(This article belongs to the Special Issue Emerging Therapies in Renal Cell Carcinoma)

Round 1

Reviewer 1 Report

The manuscript draft contains brief account of current therapies and ongoing clinical trials for RCC. The review is very well written with attention to detail and potential impact of adjuvant therapy in clear cell renal cell carcinoma. 

The manuscript can be accepted in its present form. Nonetheless, it would be great if authors could add their view on future studies and research breakthroughs that would impact the field at the end of the conclusion (For example the ongoing discoveries of biomarkers as mentioned in the manuscript). I do understand the focus of the manuscript is the clinical trials but the lesson learned from these and a way forward would be much appreciated by the readers.  

Author Response

Please see the attachment. 

Author Response File: Author Response.docx

Reviewer 2 Report

Well-written comprehensive review of adjuvant treatment options in clear cell renal cell carcinoma. Recommend accepting for publication in current form. 

Author Response

Please see the attachment. 

Author Response File: Author Response.docx

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