Using mHealth Technology to Evaluate Daily Symptom Burden among Adult Survivors of Childhood Cancer: A Feasibility Study
Abstract
:Simple Summary
Abstract
1. Introduction
2. Methods
2.1. Study Design
2.2. Data Collection
2.3. PRO Assessment
2.4. Satisfaction Survey
2.5. Covariates
2.6. Statistical Analysis
3. Results
4. Discussion
Supplementary Materials
Author Contributions
Funding
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Characteristics | N (%) or Mean (SD; Min, Max) |
---|---|
Age at study enrollment (in years) | 34.0 (5.3; 25.7, 47.1) |
Age at study enrollment (%) | |
18–29.9 years | 10 (24) |
30–39.9 years | 24 (59) |
≥40 years | 7 (17) |
Time since cancer diagnosis (in years) | 26.1 (3.7; 19.5, 32.4) |
Time since cancer diagnosis (%) | |
10–19 years | 3 (7) |
20–29 years | 28 (68) |
≥30 years | 10 (24) |
Sex (%) | |
Male | 14 (34) |
Female | 27 (66) |
Race/Ethnicity (%) | |
White non-Hispanic | 30 (73) |
Black non-Hispanic | 11 (27) |
Educational Attainment | |
High school/GED or less | 6 (15) |
Some college or post-high school training | 21 (51) |
College graduate or post-graduate level | 14 (34) |
Cancer diagnosis (%) | |
Central nervous system tumor | 15 (37) |
Acute lymphoblastic leukemia | 8 (20) |
Wilms tumor | 5 (12) |
Non-Hodgkin lymphoma | 5 (12) |
Hodgkin lymphoma | 2 (5) |
Neuroblastoma | 2 (5) |
Rhabdomyosarcoma | 2 (5) |
Osteosarcoma | 1 (2) |
Ewing sarcoma | 1 (2) |
Cancer Treatment | |
Chemotherapy (%) | 25 (61) |
Radiation (%) | 11 (27) |
Invasive surgery (%) | 32 (78) |
PROMIS-29 Profile reported in Month 3 | |
Anxiety Interference | 56.3 (9.6; 40.3, 73.4) |
Depression Interference | 55.7 (10.4; 41.0, 79.3) |
Fatigue Interference | 54.5 (11.8; 33.7, 75.8) |
Sleep Interference | 56.0 (9.5; 36.9, 73.3) |
Pain Interference | 54.0 (10.9; 41.6, 75.6) |
Neuro-QOL reported in Month 3 | |
Cognitive Function | 47.1 (11.2; 22.8, 64.2) |
Questions | Strongly Agree/Agree | Neutral | Strongly Disagree/Disagree |
---|---|---|---|
It was easy for me to complete brief daily symptom evaluations (e.g., a few days in a week) over the past 3 months | 35 (89.7%) | 2 (5.1%) | 2 (5.1%) |
I would be willing to take part in symptom evaluations on a regular basis to help doctors understand more | 35 (89.7%) | 3 (7.7%) | 1 (2.6%) |
I would be willing to take part in symptom evaluations 2–3 times per day to help doctors learn the symptom changes on a daily basis | 26 (66.7%) | 9 (23.1%) | 4 (10.3%) |
I am interested in taking part in a clinical trial to help doctors use my symptom data for advancing treatment strategies | 31 (79.5%) | 8 (20.5%) | 0 (0%) |
In future studies, I would be interested in receiving a report after my symptom evaluations are done | 32 (82.1%) | 5 (12.8%) | 2 (5.1%) |
I am interested in discussing problematic symptoms with my oncologists or primary care physicians | 30 (76.9%) | 9 (23.1%) | 0 (0%) |
I am interested in learning skills for self-managing my problematic symptoms | 34 (87.2%) | 5 (12.8%) | 0 (0%) |
I believe that effective symptom control may improve my quality of life | 31 (79.5%) | 7 (17.9%) | 1 (2.6%) |
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Share and Cite
Howell, K.E.; Baedke, J.L.; Bagherzadeh, F.; McDonald, A.; Nathan, P.C.; Ness, K.K.; Hudson, M.M.; Armstrong, G.T.; Yasui, Y.; Huang, I.-C. Using mHealth Technology to Evaluate Daily Symptom Burden among Adult Survivors of Childhood Cancer: A Feasibility Study. Cancers 2024, 16, 2984. https://doi.org/10.3390/cancers16172984
Howell KE, Baedke JL, Bagherzadeh F, McDonald A, Nathan PC, Ness KK, Hudson MM, Armstrong GT, Yasui Y, Huang I-C. Using mHealth Technology to Evaluate Daily Symptom Burden among Adult Survivors of Childhood Cancer: A Feasibility Study. Cancers. 2024; 16(17):2984. https://doi.org/10.3390/cancers16172984
Chicago/Turabian StyleHowell, Kristen E., Jessica L. Baedke, Farideh Bagherzadeh, Aaron McDonald, Paul C. Nathan, Kirsten K. Ness, Melissa M. Hudson, Gregory T. Armstrong, Yutaka Yasui, and I-Chan Huang. 2024. "Using mHealth Technology to Evaluate Daily Symptom Burden among Adult Survivors of Childhood Cancer: A Feasibility Study" Cancers 16, no. 17: 2984. https://doi.org/10.3390/cancers16172984