Synthetic Methods and Applications of Carbon Nanodots

Round 1

Reviewer 1 Report

1) The figures in the paper are suggested to be provided in high resolution.

2) In line 621, the authors write that the imaging of deeper tissue samples is a prospective use for CDs with NIR emission properties. Have these CDs with NIR emission properties been developed? If so, it is recommended to add the corresponding content to describe it.

3) The contents of Section 3.2 and Section 3.8 seem to be somewhat repetitive. Can they be merged?

4) There are many grammar mistakes, such as “There is various applications which is associated with carbon dots. CDs also show number of biomedical application”. Please have the manuscript reviewed for clarity, and corrected by someone with expertise in technical English editing. Also, many format errors exist that are not conducive to smooth reading. Please revise and review the paper carefully before resubmitting it. 

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Reviewer 2 Report

This review article by Srivastava et al. focused on the syntheses and applications of carbon nanodots, which they emphasized “comprehensive understanding” in their title, for which, I disagree. The shape of this review article looks like a list of 215 referred papers without any deep connection between them, this of course could not be claimed as “comprehensive understanding” in my opinion. The paper could be accepted after considering the points listed follows:

1, A clear connection between different synthetic methods should be clearly outlined, for which, the pros/cons of each method are recommended to be put together in one figure/table.

2, The authors mentioned the separation in the paper, however, without any deep discussion, I think the separation is a tough challenge and deserves a deep discussion on the problems/solutions, which may push the field much further.

3, The application section should be carefully organized. Such as Figure 8, it makes no sense to separate APPLICATIONS OF CARBON DOTS and BIOMEDICAL APPLICATIONS OF CARBON DOTS. In each part of the application, a simple list of the referred papers is not acceptable. Since the application strongly depends on how one gets the carbon dots, i.e., the composition of the material, the authors must mention how to get the carbon dots, which should be related to the part of synthetic methods to make the description clear and straightforward.

4, Conclusion part deserves more specific discussion, the sentences such as “Despite a lot of advancement in the field of carbon nanodots there is still room for improvement in its synthetic methods. Several bio-related fields are left undiscovered that needs special attention.” should be avoided.

 

5, A lot of typos without space between words appeared in the paper. “producing a brilliant yellow fluorescence in the UV range” is strange in my opinion. 

Author Response

Please see the attachment

Author Response File: Author Response.docx

Round 2

Reviewer 1 Report

Accept in present form.

Reviewer 2 Report

The authors made sufficient revisions and I believe the manuscript was improved significantly. Publication on the present shape is recommended.