Pyrrole Plasma Polymer-Coated Electrospun Scaffolds for Neural Tissue Engineering
Abstract
:1. Introduction
2. Materials and Methods
2.1. Fabrication of Fibrous Composite Scaffolds
2.1.1. Electrospinning
2.1.2. Pyrrole Plasma Polymer Coating
2.2. Characterization of the Scaffolds
2.2.1. Physicochemical Characterization
2.2.2. Morphology and Microstructure
2.2.3. Biological Characterization
2.2.4. Statistical Analysis
3. Results and Discussion
3.1. Physicochemical Characterization
3.2. Morphological Characterization
3.3. Biological Characterization
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Scaffold | 16.7° Peak Intensity | 19° Peak Intensity | Degree of Crystallinity |
---|---|---|---|
rPLA | - | - | 0.07 |
aPLA | - | - | 0.14 |
rPLA+pPPy | 629 | - | 0.06 |
aPLA+pPPy | 1821 | 401 | 0.18 |
rPLA+pPPy/I | 1669 | 411 | 0.16 |
aPLA+pPPy/I | 3728 | 410 | 0.19 |
Scaffolds | PLA | PLA+pPPy | PLA+pPPy/I |
---|---|---|---|
Tg (°C) | 60 | 56.5 | 60 |
Tcc (°C) | 87.44 | 121.04 | 106.73 |
Tm (°C) | 167.58 | 159.47 | 163.25 |
Tm1 (°C) | - | 153.65 | 158 |
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Osorio-Londoño, D.M.; Godínez-Fernández, J.R.; Acosta-García, M.C.; Morales-Corona, J.; Olayo-González, R.; Morales-Guadarrama, A. Pyrrole Plasma Polymer-Coated Electrospun Scaffolds for Neural Tissue Engineering. Polymers 2021, 13, 3876. https://doi.org/10.3390/polym13223876
Osorio-Londoño DM, Godínez-Fernández JR, Acosta-García MC, Morales-Corona J, Olayo-González R, Morales-Guadarrama A. Pyrrole Plasma Polymer-Coated Electrospun Scaffolds for Neural Tissue Engineering. Polymers. 2021; 13(22):3876. https://doi.org/10.3390/polym13223876
Chicago/Turabian StyleOsorio-Londoño, Diana María, José Rafael Godínez-Fernández, Ma. Cristina Acosta-García, Juan Morales-Corona, Roberto Olayo-González, and Axayácatl Morales-Guadarrama. 2021. "Pyrrole Plasma Polymer-Coated Electrospun Scaffolds for Neural Tissue Engineering" Polymers 13, no. 22: 3876. https://doi.org/10.3390/polym13223876