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Volume 13
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10.3390/life13010104
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Review

Updates in the Field of Submucosal Endoscopy

by
Tadateru Maehata
*,
Yoshinori Sato
,
Yusuke Nakamoto
,
Masaki Kato
,
Akiyo Kawashima
,
Hirofumi Kiyokawa
,
Hiroshi Yasuda
,
Hiroyuki Yamamoto
and
Keisuke Tateishi
Division of Gastroenterology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki 216-8511, Japan
*
Author to whom correspondence should be addressed.
Life 2023, 13(1), 104; https://doi.org/10.3390/life13010104
Submission received: 19 November 2022 / Revised: 24 December 2022 / Accepted: 26 December 2022 / Published: 30 December 2022
(This article belongs to the Special Issue Advances in Endoscopic Therapy for Gastrointestinal Disease)
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Abstract

Submucosal endoscopy (third-space endoscopy) can be defined as an endoscopic procedure performed in the submucosal space. This procedure is novel and has been utilized for delivery to the submucosal space in a variety of gastrointestinal diseases, such as a tumor, achalasia, gastroparesis, and subepithelial tumors. The main submucosal endoscopy includes peroral endoscopic myotomy, gastric peroral endoscopic myotomy, Zenker peroral endoscopic myotomy, submucosal tunneling for endoscopic resection, and endoscopic submucosal tunnel dissection. Submucosal endoscopy has been used as a viable alternative to surgical techniques because it is minimally invasive in the treatment and diagnosis of gastrointestinal diseases and disorders. However, there is limited evidence to prove this. This article reviews the current applications and evidence regarding submucosal endoscopy while exploring the possible future clinical applications in this field. As our understanding of these procedures improves, the future of submucosal endoscopy could be promising in the fields of diagnostic and therapeutic endoscopy.
Keywords: submucosal endoscopy; third space endoscopy; peroral endoscopic myotomy (POEM); endoscopic submucosal dissection (ESD); submucosal tunnel endoscopic resection (STER); gastric peroral endoscopic myotomy (G-POEM); Zenker’s peroral endoscopic myotomy (Z-POEM); pocket-creation method (PCM); water pressure method submucosal endoscopy; third space endoscopy; peroral endoscopic myotomy (POEM); endoscopic submucosal dissection (ESD); submucosal tunnel endoscopic resection (STER); gastric peroral endoscopic myotomy (G-POEM); Zenker’s peroral endoscopic myotomy (Z-POEM); pocket-creation method (PCM); water pressure method

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MDPI and ACS Style

Maehata, T.; Sato, Y.; Nakamoto, Y.; Kato, M.; Kawashima, A.; Kiyokawa, H.; Yasuda, H.; Yamamoto, H.; Tateishi, K. Updates in the Field of Submucosal Endoscopy. Life 2023, 13, 104. https://doi.org/10.3390/life13010104

AMA Style

Maehata T, Sato Y, Nakamoto Y, Kato M, Kawashima A, Kiyokawa H, Yasuda H, Yamamoto H, Tateishi K. Updates in the Field of Submucosal Endoscopy. Life. 2023; 13(1):104. https://doi.org/10.3390/life13010104

Chicago/Turabian Style

Maehata, Tadateru, Yoshinori Sato, Yusuke Nakamoto, Masaki Kato, Akiyo Kawashima, Hirofumi Kiyokawa, Hiroshi Yasuda, Hiroyuki Yamamoto, and Keisuke Tateishi. 2023. "Updates in the Field of Submucosal Endoscopy" Life 13, no. 1: 104. https://doi.org/10.3390/life13010104

APA Style

Maehata, T., Sato, Y., Nakamoto, Y., Kato, M., Kawashima, A., Kiyokawa, H., Yasuda, H., Yamamoto, H., & Tateishi, K. (2023). Updates in the Field of Submucosal Endoscopy. Life, 13(1), 104. https://doi.org/10.3390/life13010104

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