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Review

Technology and Future of Multi-Cancer Early Detection

by
Danny A. Milner, Jr.
1,2,* and
Jochen K. Lennerz
3
1
Harvard T. H. Chan School of Public Health, Harvard University, Boston, MA 02115, USA
2
Union for International Cancer Control, 1202 Geneva, Switzerland
3
BostonGene, Waltham, MA 02453, USA
*
Author to whom correspondence should be addressed.
Life 2024, 14(7), 833; https://doi.org/10.3390/life14070833
Submission received: 21 May 2024 / Revised: 25 June 2024 / Accepted: 26 June 2024 / Published: 29 June 2024
(This article belongs to the Special Issue Novel Approaches to Early Cancer Detection)

Abstract

Cancer remains a significant global health challenge due to its high morbidity and mortality rates. Early detection is essential for improving patient outcomes, yet current diagnostic methods lack the sensitivity and specificity needed for identifying early-stage cancers. Here, we explore the potential of multi-omics approaches, which integrate genomic, transcriptomic, proteomic, and metabolomic data, to enhance early cancer detection. We highlight the challenges and benefits of data integration from these diverse sources and discuss successful examples of multi-omics applications in other fields. By leveraging these advanced technologies, multi-omics can significantly improve the sensitivity and specificity of early cancer diagnostics, leading to better patient outcomes and more personalized cancer care. We underscore the transformative potential of multi-omics approaches in revolutionizing early cancer detection and the need for continued research and clinical integration.
Keywords: biomarker; early detection; precision oncology biomarker; early detection; precision oncology

Share and Cite

MDPI and ACS Style

Milner, D.A., Jr.; Lennerz, J.K. Technology and Future of Multi-Cancer Early Detection. Life 2024, 14, 833. https://doi.org/10.3390/life14070833

AMA Style

Milner DA Jr., Lennerz JK. Technology and Future of Multi-Cancer Early Detection. Life. 2024; 14(7):833. https://doi.org/10.3390/life14070833

Chicago/Turabian Style

Milner, Danny A., Jr., and Jochen K. Lennerz. 2024. "Technology and Future of Multi-Cancer Early Detection" Life 14, no. 7: 833. https://doi.org/10.3390/life14070833

APA Style

Milner, D. A., Jr., & Lennerz, J. K. (2024). Technology and Future of Multi-Cancer Early Detection. Life, 14(7), 833. https://doi.org/10.3390/life14070833

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