The Use of 13C-Urea Breath Test for Non-Invasive Diagnosis of Helicobacter pylori Infection in Comparison to Endoscopy and Stool Antigen Test
, Ibrahim Al rfoa 3, Amin Aqel 1, Mohammad Abu-Lubad 1, Omar Hamdan 4 and Kareem Jaber 5Round 1
Reviewer 1 Report
The manuscript is quite well written.
The authors demonstrated that 13C UBT was found to be more sensitive and accurate than stool antigen test when used for diagnosis; and it has a comparable outcome to stool antigen test in assessing successfulness of the eradication treatment.
The methods are adequate.
The results justify the conclusions drawn.
Reviewer 2 Report
In this paper the authors investigate the sensitivity and specificity of UBT labeled with 13C in diagnosis of H. pylori, and in assessing the successfulness of eradication therapy. The results of UBT will be compared to endoscopy as the gold standard invasive test, and to fecal stool antigen test as a non-invasive test.
Overall the manuscript is well organized and well written.
