Multi-Channel Based Image Processing Scheme for Pneumonia Identification
Abstract
:1. Introduction
- We preprocess our CXR images into three forms, namely: LBP, CLAHE, and CECED.
- Each preprocessed image features are extracted individually, that is the LBP CXR features are extracted using the shallow CNN, the CECED CXR features are extracted using the MobileNet-V3 and the CLAHE CXR feature images are extracted using the Inception v3.
- The feature vectors of these preprocessed CXR images are weighted fused for a robust prediction result.
- We evaluate the performance of each of the single models and our proposed model in this study.
2. Related Works
- Several DL techniques are thoroughly implemented for the classification task.
- The popular medical mode of imaging for the classification and detection of pneumonia-related ailment is the chest X-ray.
- The publishers focus on either binary classification or multi-classification, although just a few considered the multi-classification task.
3. Materials and Methods
3.1. Datasets
3.2. Data Preprocessing
3.2.1. Local Binary Pattern (LBP) Images
3.2.2. CLAHE Images
- The generation of the image transformation using the bin value of the histogram is the first stage of the CLAHE technique.
- Following that, using clip boundary, the contrast is confined to a binary count from 0 to 1. Before the image segment is processed, the clip boundary is added to the image.
- To prevent mapping background areas to gray scale, a specific bin value from the histogram region is used to create the entire image region. Clip boundary is used with the help of histogram clip to obtain better mapping.
- Finally, the finished CLAHE image is created by computing the image’s regions, then extracting, mapping, and interpolating all of the image pixels to get the most out of the image.
3.2.3. CECED Images
- Collection of the original pixel’s value, as well as the local minimum and maximum;
- The image’s morphological contrast is increased;
- To reduce noise, Gaussian smoothing is applied;
- The intensity gradient of the image is determined;
- A non-maximum suppression method is utilized;
- The hysteresis thresholding technique is adopted.
3.3. Feature Extraction
3.3.1. Features Extraction from LBP Images
3.3.2. Features Extraction from CECED CXR Images
3.3.3. Features Extraction from CLAHE CXR Images
3.4. Weighted Fusion of the Different Output Channels
4. Results
4.1. Experimental Setup and Configuration
4.2. Performance Metrics
4.3. Evaluation of the Single Model
4.3.1. Shallow CNN
4.3.2. Pretrained MobileNet-V3
4.3.3. Pretrained Inception-V3
4.4. Evaluation of the Weighted Fusion
4.5. Result of the Proposed Model
5. Discussion
5.1. Ablation Study
5.1.1. Hyperparameter Tuning
5.1.2. Raw X-ray Image Feature
6. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Authors | Year | Mode of Imaging | DL Techniques | Classification Task | Evaluation Results |
---|---|---|---|---|---|
Cicero et al. [19] | 2017 | X-ray Image | GoogLeNet is utilized to classify two classes - normal and abnormal images | Binary class | For normal class: SEN = 91%, SPE = 91%, and UC = 96.4% For abnormal class: SEN (within 74% to 91%), SPE (within 75% to 91%), and AUC (within 85% to 96.2%) |
Guendel et al. [20] | 2018 | X-ray Image | Used location-aware dense networks technique to identify anomalies in chest X-rays | Multiple class | PLCO dataset, mean AUC = 87.4%, Chest X-ray 14 dataset, mean AUC = 84.1% |
Rajaraman et al. [21] | 2018 | X-ray Image | A modified VGG16 is employed for the identification and detection of viral and bacterial pneumonia | Binary class | ACC (within 91.8% to 96.2%) |
Correa et al. [22] | 2018 | Ultrasound Image | Detection of pneumonia using 3 layers feed-forward neural network | Binary class | SEN = 90.9% SPE = 100% |
Ke et al. [23] | 2019 | X-ray Image | Detection of lung diseases using an approach called neuroheuristic | Multiple class | Sensitivity = 84.22%, Accuracy = 79.06%, Specificity = 66.7% |
Saraiva et al. [24] | 2019 | X-ray Image | A CNN model was applied on a dataset of 5863 images and cross-validation was used for the validation of the model | Binary class | Accuracy = 95.30% |
Sirazitdinov et al. [25] | 2019 | X-ray Image | An emsemble of RetinaNet and Mask RCNN was applied | Binary class | Precision = 75.0%, Recall = 79%, F1-score = 77.0% |
Liang and Zheng [26] | 2020 | X-ray Image | A modified 49 convolutional and 2 fully connected layer of a CNN model was used for the classification of children’s lung regions | Binary class | F1-score = 92.7% |
Apostolopoulos et al. [27] | 2020 | X-ray Image | Different fine-tuning approaches were evaluated for the automatic detection of pneumonia | Binary class | VGG19 has the highest value of: Sensitivity = 92.85%, Specificity = 98.75%, Accuracy = 98.75% |
Xu et al. [28] | 2020 | X-ray Image | Multiple CNN models were compared in order to categorize the classes of CT scans | Multiple class | Accuracy = 86.7% |
Habib et al. [29] | 2020 | X-ray Image | Detection of pneumonia using an ensemble of VGG-19 and CheXNet for the extraction of features and random forest as the classifier | Binary class | Accuracy = 98.93% |
Chouhan et al. [30] | 2020 | X-ray Image | A transfer learning technique is applied for the detection of pneumonia | Binary class | Accuracy = 96.4% Sensitivity 99.0% |
El Asnaoui et al. [31] | 2020 | X-ray Image | A fine-tuned of eight different models for the detection and classification of pneumonia | Binary class | Highest accuracy is the fine-tubed ResNet50 (>96%) |
El Asnaoui et al. [32] | 2020 | X-ray Image | A comparative findings of seven DL models for the classification and detection of pneumonia (including COVID-19) | Multiple class | Accuracy Evaluations: InceptionResNet-V2 = 92.18%, DenseNet201 = 88.09% |
Dataset | Pneumonia Category | Value | Selected Amount Used |
---|---|---|---|
Kaggle database of RSNA [33] | Bacterial | 3029 | 1000 |
Viral | 2983 | 1000 | |
Normal | 8851 | 1000 | |
Rahman et al. [34] | COVID-19 | 3616 | 1000 |
Input | Operator | Expansion Size | Output | SE | NL | Stride |
---|---|---|---|---|---|---|
224 × 224 × 3 | Conv2d, 3 × 3 | - | 16 | No | HS | 2 |
112 × 112 × 16 | bneck, 3 × 3 | 16 | 16 | Yes | RE | 2 |
56 × 56 × 16 | bneck, 3 × 3 | 72 | 24 | No | RE | 2 |
28 × 28 × 24 | bneck, 3 × 3 | 86 | 24 | No | RE | 1 |
28 × 28 × 24 | bneck, 5 × 5 | 96 | 40 | Yes | HS | 2 |
14 × 14 × 40 | bneck, 5 × 5 | 240 | 40 | Yes | HS | 1 |
14 × 14 × 40 | bneck, 5 × 5 | 240 | 40 | Yes | HS | 1 |
14 × 14 × 40 | bneck, 5 × 5 | 120 | 48 | Yes | HS | 1 |
14 × 14 × 48 | bneck, 5 × 5 | 144 | 48 | Yes | HS | 1 |
7 × 7 × 96 | bneck, 5 × 5 | 288 | 96 | Yes | HS | 2 |
7 × 7 × 96 | bneck, 5 × 5 | 576 | 96 | Yes | HS | 1 |
7 × 7 × 96 | bneck, 5 × 5 | 576 | 96 | Yes | HS | 1 |
7 × 7 × 256 | Conv2d, 1 × 1 | - | 256 | Yes | HS | 1 |
1 × 1 × 256 | Avg pool, 7 × 7 | - | - | No | - | 1 |
1 × 1 × 512 | Conv2d, 1 × 1 | - | 512 | No | HS | 1 |
Model | ACC (%) | SEN (%) | SPE (%) | PRE (%) | F1-s (%) | Time (min) |
---|---|---|---|---|---|---|
LBP-Channel Shallow CNN (LCSC) | 90.9 | 92.3 | 93.1 | 91.2 | 92.7 | 3.2 |
CECED-Channel MobileNet-V3 (CCM) | 93.7 | 95.4 | 95.7 | 94.3 | 95.5 | 18.6 |
CLAHE-Channel Inception-V3 (CCI) | 95.6 | 94.9 | 96.2 | 95.8 | 95.3 | 21.8 |
LBP-Channel Shallow CNN + CECED-channel MobileNet-V3 (LCSC + CCM) | 92.2 | 93.7 | 94.5 | 92.7 | 94.3 | 23.4 |
LBP-Channel Shallow CNN + CLAHE-channel Inception-V3 (LCSC + CCI) | 94.4 | 95.5 | 96.8 | 95.1 | 96.6 | 22.7 |
CLAHE-Channel inception-V3 + CECED-channel MobileNet-V3 (CCI + CCM) | 97.5 | 97.3 | 98.3 | 97.8 | 98.1 | 26.8 |
LBP-Channel Shallow CNN + CLAHE-channel Inception-V3 + CECED-channel MobileNet-V3 (LCSC + CCI + CCM) | 98.3 | 98.9 | 99.2 | 98.8 | 99.0 | 30.3 |
Authors | ACC (%) | SEN (%) | SPE (%) |
---|---|---|---|
Cicero et al. [19] | 91.0 | 91.0 | 91.0 |
Correa et al. [22] | - | 90.9 | 100.0 |
Apostolopoulos et al. [27] | 98.0 | 92.9 | 98.8 |
Xu et al. [28] | 86.7 | 86.9 | - |
Habib et al. [29] | 98.93 | - | - |
Chouchan et al. [30] | 96.4 | 99.6 | - |
Yamaç et al. [35] | 86.5 | 79.2 | 90.7 |
Wang et al. [36] | 93.3 | 90.7 | 95.5 |
Li et al. [37] | 96.9 | 97.8 | 94.9 |
J.K. K. Singh and A. Singh [38] | 95.8 | 96.1 | 95.7 |
Yang et al. [39] | 88.4 | 64.7 | 92.9 |
Wang et al. [40] | 94.5 | 94.7 | 97.3 |
Alsharif et al. [41] | 99.7 | 99.7 | 99.8 |
Alqudah et al. [42] | 93.9 | 93.2 | 96.6 |
Alquran et al. [43] | 93.1 | 92.9 | 96.4 |
Masad et al. [44] | 98.9 | 98.3 | 99.2 |
Our Model | 98.3 | 98.9 | 99.2 |
Model | ACC (%) | SEN (%) | SPE (%) |
---|---|---|---|
Xu et al. [28] | 91.2 | 91.8 | 93.1 |
Wang et al. [36] | 94.0 | 92.9 | 94.2 |
Li et al. [37] | 96.1 | 94.4 | 95.5 |
Yang et al. [39] | 93.5 | 92.4 | 94.7 |
Wang et al. [40] | 95.8 | 95.4 | 96.4 |
Our Model | 98.3 | 98.9 | 99.2 |
Model | LBP-Based Channel | CECED-Based Channel | CLAHE-Based Channel | ||||||
---|---|---|---|---|---|---|---|---|---|
ACC (%) | SEN (%) | SPE (%) | ACC (%) | SEN (%) | SPE (%) | ACC (%) | SEN (%) | SPE (%) | |
AlexNet | 89.2 | 91.4 | 92.6 | 89.3 | 87.5 | 90.2 | 92.5 | 94.3 | 93.7 |
VGG-16 | 88.9 | 90.7 | 91.4 | 90.9 | 90.1 | 91.8 | 91.4 | 92.8 | 91.9 |
ResNet-152 | 84.6 | 86.2 | 87.9 | 91.4 | 92.3 | 93.1 | 87.8 | 88.1 | 87.6 |
MobileNet-V3 | 87.7 | 89.4 | 90.5 | 93.7 | 95.4 | 95.7 | 90.4 | 91.6 | 90.8 |
DenseNet-121 | 85.3 | 87.1 | 88.7 | 92.8 | 92.8 | 93.3 | 88.4 | 89.2 | 88.7 |
Inception-V3 | 86.3 | 88.6 | 89.4 | 93.1 | 91.5 | 93.7 | 95.6 | 94.9 | 96.2 |
Shallow CNN | 90.9 | 92.3 | 93.1 | 87.2 | 86.1 | 88.4 | 85.9 | 86.2 | 85.7 |
Hyperparameters | (LCSC + Adam) | (CCI + Adam) | (CCM + Adam) | (LCSC + CCI + Adam) | (LCSC + CCM + Adam) | (CCI + CCM + Adam) | (LCSC + CCI + CCM + Adam) |
---|---|---|---|---|---|---|---|
Accuracy (%) | Accuracy (%) | Accuracy (%) | Accuracy (%) | Accuracy (%) | Accuracy (%) | Accuracy (%) | |
LR (0.1) + Dropout (0.25) | 87.5 | 81.6 | 89.6 | 87.3 | 85.6 | 90.2 | 88.1 |
LR (0.1) + Dropout (0.50) | 86.9 | 87.3 | 90.7 | 89.6 | 87.4 | 89.5 | 87.6 |
LR (0.1) + Dropout (0.75) | 83.6 | 82.6 | 87.9 | 89.9 | 89.3 | 91.7 | 89.2 |
LR (0.01) + Dropout (0.25) | 81.4 | 85.1 | 91.1 | 90.4 | 91.7 | 90.4 | 87.1 |
LR (0.01) + Dropout (0.50) | 89.8 | 84.9 | 86.3 | 91.1 | 90.8 | 85.5 | 88.4 |
LR (0.01) + Dropout (0.75) | 84.7 | 90.7 | 92.8 | 85.7 | 89.2 | 87.8 | 89.7 |
LR (0.001) + Dropout (0.25) | 82.2 | 95.6 | 88.2 | 84.6 | 92.1 | 92.1 | 91.5 |
LR (0.001) + Dropout (0.50) | 80.7 | 91.3 | 93.4 | 86.5 | 89.7 | 94.7 | 92.6 |
LR (0.001) + Dropout (0.75) | 88.3 | 92.7 | 93.7 | 91.4 | 90.8 | 89.6 | 93.8 |
LR (0.0001) + Dropout (0.25) | 85.9 | 83.4 | 85.6 | 87.9 | 92.4 | 96.3 | 97.4 |
LR (0.0001) + Dropout (0.50) | 90.9 | 80.6 | 87.1 | 94.4 | 92.2 | 97.5 | 98.3 |
LR (0.0001) + Dropout (0.75) | 79.5 | 86.2 | 88.9 | 89.8 | 93.3 | 95.7 | 95.9 |
Hyperparameters | (LCSC + RMSProp) | (CCI + RMSProp) | (CCM + RMSProp) | (LCSC + CCI + RMSProp) | (LCSC + CCM + RMSProp) | (CCI + CCM + RMSProp) | (LCSC + CCI + CCM + RMSProp) |
---|---|---|---|---|---|---|---|
Accuracy (%) | Accuracy (%) | Accuracy (%) | Accuracy (%) | Accuracy (%) | Accuracy (%) | Accuracy (%) | |
LR (0.1) + Dropout (0.25) | 88.5 | 89.1 | 88.9 | 87.6 | 90.7 | 89.7 | 90.1 |
LR (0.1) + Dropout (0.50) | 89.7 | 87.4 | 89.5 | 87.2 | 89.5 | 90.3 | 91.3 |
LR (0.1) + Dropout (0.75) | 86.3 | 90.7 | 88.1 | 89.3 | 89.6 | 91.6 | 89.8 |
LR (0.01) + Dropout (0.25) | 87.7 | 88.2 | 89.6 | 88.4 | 88.4 | 92.5 | 91.6 |
LR (0.01) + Dropout (0.50) | 81.4 | 91.5 | 91.2 | 90.6 | 90.9 | 90.9 | 93.4 |
LR (0.01) + Dropout (0.75) | 81.1 | 89.8 | 90.4 | 89.7 | 91.6 | 92.1 | 92.8 |
LR (0.001) + Dropout (0.25) | 83.8 | 92.3 | 92.2 | 88.9 | 90.1 | 91.4 | 94.4 |
LR (0.001) + Dropout (0.50) | 86.5 | 89.6 | 94.3 | 87.3 | 93.7 | 93.7 | 96.5 |
LR (0.001) + Dropout (0.75) | 84.2 | 90.9 | 93.5 | 90.4 | 92.4 | 95.3 | 95.9 |
LR (0.0001) + Dropout (0.25) | 85.9 | 91.1 | 94.7 | 91.8 | 93.6 | 94.5 | 97.4 |
LR (0.0001) + Dropout (0.50) | 88.6 | 89.5 | 93.9 | 90.6 | 92.9 | 93.9 | 96.2 |
LR (0.0001) + Dropout (0.75) | 85.3 | 88.9 | 94.6 | 89.7 | 91.5 | 92.6 | 95.5 |
Hyperparameters | (LCSC + SGD) | (CCI + SGD) | (CCM + SGD) | (LCSC + CCI + SGD) | (LCSC + CCM + SGD) | (CCI + CCM + SGD) | (LCSC + CCI + CCM + SGD) |
---|---|---|---|---|---|---|---|
Accuracy (%) | Accuracy (%) | Accuracy (%) | Accuracy (%) | Accuracy (%) | Accuracy (%) | Accuracy (%) | |
LR (0.1) + Dropout (0.25) | 87.2 | 88.8 | 87.7 | 86.1 | 87.1 | 90.8 | 89.7 |
LR (0.1) + Dropout (0.50) | 85.5 | 89.3 | 88.1 | 88.5 | 89.6 | 89.1 | 90.5 |
LR (0.1) + Dropout (0.75) | 87.9 | 97.5 | 89.5 | 87.9 | 88.2 | 90.9 | 91.6 |
LR (0.01) + Dropout (0.25) | 89.1 | 90.9 | 91.9 | 89.7 | 89.7 | 91.7 | 89.1 |
LR (0.01) + Dropout (0.50) | 82.3 | 92.3 | 90.3 | 91.5 | 91.4 | 92.3 | 91.3 |
LR (0.01) + Dropout (0.75) | 83.6 | 88.7 | 89.5 | 90.3 | 90.1 | 90.8 | 93.5 |
LR (0.001) + Dropout (0.25) | 84.9 | 91.9 | 91.7 | 89.1 | 91.2 | 92.5 | 92.7 |
LR (0.001) + Dropout (0.50) | 85.7 | 90.4 | 92.4 | 90.5 | 92.5 | 91.6 | 95.9 |
LR (0.001) + Dropout (0.75) | 83.5 | 91.6 | 94.1 | 91.9 | 93.8 | 94.9 | 94.4 |
LR (0.0001) + Dropout (0.25) | 86.3 | 89.3 | 93.3 | 89.7 | 92.9 | 95.3 | 96.2 |
LR (0.0001) + Dropout (0.50) | 87.1 | 90.8 | 94.6 | 91.5 | 93.6 | 92.5 | 95.6 |
LR (0.0001) + Dropout (0.75) | 88.8 | 89.2 | 93.0 | 90.3 | 92.3 | 93.7 | 96.8 |
Model | ACC (%) | SEN (%) | SPE (%) | PRE (%) | F1 (%) |
---|---|---|---|---|---|
Raw image Shallow CNN (RISC) | 82.1 | 83.6 | 80.8 | 82.9 | 83.3 |
Raw image MobileNet-V3 (RIM) | 88.0 | 89.2 | 90.5 | 89.7 | 89.0 |
Raw image Inception-V3 (RII) | 93.34 | 91.5 | 92.7 | 93.0 | 91.9 |
Raw image Shallow CNN + Raw image Inception-V3 (RISC + RII) | 91.7 | 89.4 | 91.0 | 90.1 | 91.5 |
Raw image Shallow CNN + Raw image MobileNet-V3 (RISC + RIM) | 85.8 | 86.1 | 87.3 | 89.6 | 88.9 |
Raw image Inception-V3 + Raw image MobileNet-V3 (RII + RIM) | 95.2 | 94.6 | 96.1 | 94.2 | 95.7 |
Raw image Shallow CNN + Raw image Inception-V3 + Raw image MobileNet-V3 (RISC + RII + RIM) | 96.9 | 96.0 | 95.4 | 96.5 | 95.0 |
Model | Raw Image | ||
---|---|---|---|
ACC (%) | SEN (%) | SPE (%) | |
AlexNet | 90.9 | 89.1 | 91.0 |
VGG-16 | 89.6 | 90.3 | 89.2 |
ResNet-152 | 90.2 | 88.5 | 89.0 |
MobileNet-V3 | 88.0 | 89.2 | 90.5 |
DenseNet-121 | 87.7 | 89.1 | 88.3 |
Inception-V3 | 93.3 | 91.5 | 92.7 |
Shallow CNN | 82.1 | 83.6 | 80.8 |
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Nneji, G.U.; Cai, J.; Deng, J.; Monday, H.N.; James, E.C.; Ukwuoma, C.C. Multi-Channel Based Image Processing Scheme for Pneumonia Identification. Diagnostics 2022, 12, 325. https://doi.org/10.3390/diagnostics12020325
Nneji GU, Cai J, Deng J, Monday HN, James EC, Ukwuoma CC. Multi-Channel Based Image Processing Scheme for Pneumonia Identification. Diagnostics. 2022; 12(2):325. https://doi.org/10.3390/diagnostics12020325
Chicago/Turabian StyleNneji, Grace Ugochi, Jingye Cai, Jianhua Deng, Happy Nkanta Monday, Edidiong Christopher James, and Chiagoziem Chima Ukwuoma. 2022. "Multi-Channel Based Image Processing Scheme for Pneumonia Identification" Diagnostics 12, no. 2: 325. https://doi.org/10.3390/diagnostics12020325
APA StyleNneji, G. U., Cai, J., Deng, J., Monday, H. N., James, E. C., & Ukwuoma, C. C. (2022). Multi-Channel Based Image Processing Scheme for Pneumonia Identification. Diagnostics, 12(2), 325. https://doi.org/10.3390/diagnostics12020325