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Article
Peer-Review Record

Prediction of Intraparenchymal Hemorrhage Progression and Neurologic Outcome in Traumatic Brain Injury Patients Using Radiomics Score and Clinical Parameters

Diagnostics 2022, 12(7), 1677; https://doi.org/10.3390/diagnostics12071677
by Yun-Ju Shih 1, Yan-Lin Liu 2, Jeon-Hor Chen 2,3,*, Chung-Han Ho 4,5, Cheng-Chun Yang 1, Tai-Yuan Chen 1,6, Te-Chang Wu 1,7, Ching-Chung Ko 1,8, Jonathan T. Zhou 2, Yang Zhang 2,9 and Min-Ying Su 2,10
Reviewer 1:
Reviewer 2: Anonymous
Diagnostics 2022, 12(7), 1677; https://doi.org/10.3390/diagnostics12071677
Submission received: 24 May 2022 / Revised: 4 July 2022 / Accepted: 8 July 2022 / Published: 10 July 2022
(This article belongs to the Special Issue Exploring of Diagnostic Approaches in Neuro-Related Diseases)

Round 1

Reviewer 1 Report

Thanks interesting script and data. 

I think it is important to shed light on and discuss the strength and limitations of the various tests and technologies as a basis due to a general assessment.

However I think the conclusion should also state that prospective RCT studies are needed in future.

Author Response

Please see the attachment.

Author Response File: Author Response.docx

Reviewer 2 Report

The manuscript entitled “Prediction of Intraparenchymal Hemorrhage Progression and Neurologic Outcome in Traumatic Brain Injury Patients Using Radiomics Score and Clinical Parameters” is aimed to study if the combined model of radiomics score and clinical and brain volume data can better predict the incidence of Intraparenchymal Hemorrhage Progression and poor Neurologic Outcome in TBI Patients.

The authors have included the sufficient ROC curve and other data to support the conclusion. Two minor issues that can be addressed are

·        - Figure 6 is missing the ROC curve and value for the combined models.

    - Also, the authors can explain briefly if the high comorbidity % of patients especially that of diabetes incidence interfered with the observed results.

Author Response

Please see the attachment.

Author Response File: Author Response.docx

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