The Impact of the Angulus Biopsy on the Detection of Staging and the Grading of Chronic Gastritis
Abstract
:1. Introduction
2. Materials and Methods
2.1. Patient Data
2.2. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
- Taking a biopsy from the incisura angularis with subsequent analysis of structural changes in the gastric mucosa in most cases does not play a decisive role in the integral assessment of the stage of gastritis in accordance with the OLGA-system;
- In persons with a long course of chronic gastritis associated with H. pylori, the assessment of the presence and severity of atrophy of the incisura angularis is appropriate for a more accurate assessment of the stage of gastritis.
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Etiology | n | % | |
---|---|---|---|
Group 1 | Chronic gastritis associated with H. pylori | 380 | 52.9 |
Group 2 | Autoimmune gastritis | 209 | 29.1 |
Group 3 | Autoimmune gastritis in combination with chronic gastritis associated with H. pylori | 129 | 18.0 |
Total | 718 | 100 |
Detection Methods | Group 1. Chronic Gastritis Associated with H. pylori (n = 380 Patients) | Group 3. Autoimmune Gastritis in Combination with Chronic H. pylori Gastritis (n = 129 Patients) | ||
---|---|---|---|---|
Total | % | Total | % | |
13C urease breath test | 109 | 28.68% | 15 | 11.62% |
Rapid urease test | 55 | 14.47% | 26 | 20.15% |
Antibodies to H. pylori IgG | 64 | 16.84% | 25 | 19.38% |
Morphological study | 118 | 31.05% | 4 | 3.1% |
Monoclonal antigen in feces | 17 | 4.47% | 3 | 2.32% |
A doctor’s entry in the medical records about the presence of H. pylori and the performed eradication therapy | 145 | 38.26% | 56 | 43.41% |
Grade of OLGA | Total | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
0 | I | II | III | IV | ||||||||
n | % | n | % | n | % | n | % | n | % | |||
1 | Chronic gastritis associated with H. pylori | 2 | 0.5 | 14 | 3.7 | 246 | 64.7 | 95 | 25 | 23 | 6.1 | 380 |
2 | Autoimmune gastritis | 1 | 0.5 | 2 | 1 | 170 | 81.2 | 35 | 16.8 | 1 | 0.5 | 209 |
3 | Autoimmune gastritis in combination with H. pylori chronic gastritis | 0 | - | 1 | 0.8 | 103 | 79.8 | 23 | 17.8 | 2 | 1.6 | 129 |
Total | 3 | 0.4 | 17 | 2.4 | 519 | 72.3 | 153 | 21.3 | 26 | 3.6 | 718 |
Stage of OLGA | Total | |||||
---|---|---|---|---|---|---|
0 | I | II | III | IV | ||
Cases considering the incisura angularis | 139 | 98 | 82 | 51 | 10 | 380 |
Cases without considering the incisura angularis | 155 | 90 | 74 | 55 | 6 | 380 |
Total discrepancies | +16 | +8/−15 | −8 | +4 | −4 | |
Discrepancies with reduced atrophy stage | 0 | 15 | 8 | 0 | 4 | 27 (7.11%) |
Stage of OLGA | Total | |||||
---|---|---|---|---|---|---|
0 | I | II | III | IV | ||
Cases considering the incisura angularis | 7 | 6 | 35 | 141 | 20 | 209 |
Cases without considering the incisura angularis | 9 | 6 | 36 | 139 | 19 | 209 |
Discrepancies of everything | +2 | +2/−2 | +3/−2 | +1/−3 | −1 | |
Discrepancies with decreasing stage of atrophy | 0 | 2 | 2 | 3 | 1 | 8 (3.83%) |
Stage of OLGA | Total | |||||
---|---|---|---|---|---|---|
0 | I | II | III | IV | ||
Cases considering the incisura angularis | 9 | 7 | 22 | 84 | 7 | 129 |
Cases without considering the incisura angularis | 10 | 7 | 21 | 85 | 6 | 129 |
Discrepancies of everything | +1 | +1/−1 | −1 | +1 | −1 | |
Discrepancies with decreasing stage of atrophy | 0 | 1 | 1 | 0 | 1 | 3 (2.32%) |
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Khomeriki, S.G.; Bordin, D.S.; Khomeriki, N.M.; Parfenchikova, E.V.; Nikolskaya, K.A.; Ivanova, V.A.; Chebotareva, M.V.; Gretskaya, M.L.; Voynovan, I.N.; Kiriukova, M.A.; et al. The Impact of the Angulus Biopsy on the Detection of Staging and the Grading of Chronic Gastritis. Diagnostics 2023, 13, 2928. https://doi.org/10.3390/diagnostics13182928
Khomeriki SG, Bordin DS, Khomeriki NM, Parfenchikova EV, Nikolskaya KA, Ivanova VA, Chebotareva MV, Gretskaya ML, Voynovan IN, Kiriukova MA, et al. The Impact of the Angulus Biopsy on the Detection of Staging and the Grading of Chronic Gastritis. Diagnostics. 2023; 13(18):2928. https://doi.org/10.3390/diagnostics13182928
Chicago/Turabian StyleKhomeriki, Sergey G., Dmitry S. Bordin, Natalia M. Khomeriki, Elena V. Parfenchikova, Karine A. Nikolskaya, Valeria A. Ivanova, Margarita V. Chebotareva, Maria L. Gretskaya, Irina N. Voynovan, Mariia A. Kiriukova, and et al. 2023. "The Impact of the Angulus Biopsy on the Detection of Staging and the Grading of Chronic Gastritis" Diagnostics 13, no. 18: 2928. https://doi.org/10.3390/diagnostics13182928
APA StyleKhomeriki, S. G., Bordin, D. S., Khomeriki, N. M., Parfenchikova, E. V., Nikolskaya, K. A., Ivanova, V. A., Chebotareva, M. V., Gretskaya, M. L., Voynovan, I. N., Kiriukova, M. A., Livzan, M. A., & Khatkov, I. E. (2023). The Impact of the Angulus Biopsy on the Detection of Staging and the Grading of Chronic Gastritis. Diagnostics, 13(18), 2928. https://doi.org/10.3390/diagnostics13182928