Next Article in Journal
Pulmonary and Liver Toxocariasis Mimicking Metastatic Tumors in a Patient with Colon Cancer
Previous Article in Journal
The Rapid Phenotypic Susceptibility Testing in Real-Life Experience: How the MIC Values Impact on Sepsis Fast Diagnostic Workflow
Previous Article in Special Issue
The Renin-Angiotensin System: The Challenge behind Autoimmune Dermatological Diseases
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Diagnostics
Volume 14
Issue 1
10.3390/diagnostics14010057
diagnostics-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Epidemiological Study of Autoimmune Bullous Dermatoses in Northeastern Romania

by
Ioana Adriana Popescu
1,2,
Dan Vata
1,2,*,
Doinita Temelie Olinici
1,2,
Bogdan Marian Tarcau
1,2,*,
Adriana Ionela Patrascu
1,2,
Ioana Alina Halip
1,2,
Dumitrita Lenuta Gugulus
1,2,
Madalina Mocanu
1,2 and
Laura Gheuca Solovastru
1,2
1
“Saint Spiridon” County Emergency Clinical Hospital, 700111 Iasi, Romania
2
“Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, Romania
*
Authors to whom correspondence should be addressed.
Diagnostics 2024, 14(1), 57; https://doi.org/10.3390/diagnostics14010057
Submission received: 8 November 2023 / Revised: 19 December 2023 / Accepted: 21 December 2023 / Published: 26 December 2023
(This article belongs to the Special Issue Dermatology Essentials)
Browse Figures
Review Reports Versions Notes

Abstract

Background: Autoimmune bullous diseases (ABDs) are a rare but significant group of dermatoses that pose great challenges to the treating dermatologist. ABDs are characterized by the presence of tissue-bound and circulating autoantibodies directed against disease-specific target antigens of the skin. Most epidemiological studies have focused on a single ABD. More than that, there are few data about the incidence and prevalence of autoimmune blistering diseases in Romania. Methods: In this study, between 2015 and 2019, we retrospectively investigated a total of 225 patients with autoimmune bullous diseases from the northeastern region of Romania. The diagnosis was based on the clinical and histo- and immunohistological findings. Results: Pemphigus was the most frequently encountered ABD, with an incidence of 8.16/1,000,000 inhabitants, representing 58.7% (132 cases), followed by 24% cases of bullous pemphigoid (54 cases), 15.4% of patients were diagnosed with dermatitis herpetiformis (37 cases), and 0.9% other subepidermal autoimmune bullous dermatoses. The average age of onset of pemphigus vulgaris was 59.4 years, the majority of patients being male, while the average age of patients diagnosed with bullous pemphigoid was 73.8 years, the majority being female. Conclusions: Pemphigus vulgaris is the most frequently encountered ABDs in the northeast of Romania, with a higher incidence than in Western European countries, and this may be due to specific peculiarities of the geographical area, as well as to a genetic susceptibility of the population in this region.
Keywords: autoimmune bullous dermatoses; epidemiology; Northeastern Romania autoimmune bullous dermatoses; epidemiology; Northeastern Romania

Share and Cite

MDPI and ACS Style

Popescu, I.A.; Vata, D.; Temelie Olinici, D.; Tarcau, B.M.; Patrascu, A.I.; Halip, I.A.; Gugulus, D.L.; Mocanu, M.; Gheuca Solovastru, L. Epidemiological Study of Autoimmune Bullous Dermatoses in Northeastern Romania. Diagnostics 2024, 14, 57. https://doi.org/10.3390/diagnostics14010057

AMA Style

Popescu IA, Vata D, Temelie Olinici D, Tarcau BM, Patrascu AI, Halip IA, Gugulus DL, Mocanu M, Gheuca Solovastru L. Epidemiological Study of Autoimmune Bullous Dermatoses in Northeastern Romania. Diagnostics. 2024; 14(1):57. https://doi.org/10.3390/diagnostics14010057

Chicago/Turabian Style

Popescu, Ioana Adriana, Dan Vata, Doinita Temelie Olinici, Bogdan Marian Tarcau, Adriana Ionela Patrascu, Ioana Alina Halip, Dumitrita Lenuta Gugulus, Madalina Mocanu, and Laura Gheuca Solovastru. 2024. "Epidemiological Study of Autoimmune Bullous Dermatoses in Northeastern Romania" Diagnostics 14, no. 1: 57. https://doi.org/10.3390/diagnostics14010057

APA Style

Popescu, I. A., Vata, D., Temelie Olinici, D., Tarcau, B. M., Patrascu, A. I., Halip, I. A., Gugulus, D. L., Mocanu, M., & Gheuca Solovastru, L. (2024). Epidemiological Study of Autoimmune Bullous Dermatoses in Northeastern Romania. Diagnostics, 14(1), 57. https://doi.org/10.3390/diagnostics14010057

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop